Scripts 2012

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    Calcium may enhance probiotic survival in the gut, cut cholesterol levels
    Combining calcium phosphate supplements with probiotic Lactobacillus paracasei may enhance the colonization of the probiotic in the gut, and boost reductions in LDL cholesterol levels, says a new study with humans. — Calcium in the form of pentacalcium hydroxy-triphosphate, combined with Lactobacillus paracasei (LPC37) was associated with significant reductions in total and LD cholesterol following four weeks of supplementation, and the results were greater than those observed for L. paracasei alone, according to findings published in Clinical Nutrition. –“To the best of our knowledge, there are no published studies examining the influence of a combinatory supplement consisting of probiotics and calcium phosphate on the faecal microbiota and on cholesterol metabolism in humans,” wrote researchers from Friedrich Schiller University Jena in Germany. –“The results of the present human study imply that calcium phosphate positively affects the colonization of LPC37 in the human gut under conditions of combinatory supplementation of calcium phosphateand LPC37.
    “This combined supplementation is also capable of beneficially modulating blood lipids in healthy, hypercholesterolemic men and women.” –Probiotic potential – The study adds to the ever growing body of science supporting the potential benefits of probiotics. — On Tuesday, an elegant study by Dr Jeff Gordon and his team at the Washington University School of Medicine in St. Louis revealed that probiotic bacteria consumed in a yogurt may not change the host’s gut populations, but they do influence carbohydrate metabolism by the resident microbes. — The new study suggests that calcium phosphate may enhance the activities of L. paracasei. –Study details — Led by Gerhard Jahreis, the Jena, Germany-based researchers recruited 34 omnivorous men and women with moderately elevated blood cholesterol levels to participate in their double-blind, placebo-controlled, cross-over study. — Participants were divided into two groups: One was provided with a probiotic drink containing 10 billion colony forming units (CFUs) per day of L. paracasei (Danisco) for four weeks, while the second group received the probiotic plus an additional gram of pentacalcium hydroxy-triphosphate. — After the intervention period, all participants had a two week period without intervention – the so-called wash out period – followed by two weeks of receiving placebo. After this they were crossed over to the other intervention for another four weeks. — Results showed that the combined intervention was associated with a significant reduction in total and LDL cholesterol levels, compared with the probiotic alone and placebo. —“There are two possible explanations for this observation,” said the researchers, “either LPC37 and calcium phosphate act synergistically, or the cholesterol-lowering effect of LPC37 + calcium phosphate is due to the action of calcium phosphate in the human gut.” — With reference to other studies that have shown an effect of calcium supplementations on blood lipids to a similar extent as measured in the current study, the researchers proposed that the “cholesterol-lowering effect is solely due to the calcium phosphate supplement”. — In addition, the level of L. paracasei and all lactobacilli in the feces increase significantly following both the combined and probiotic only interventions, compared with placebo.
    “There was a significantly positive correlation between the fecal concentration of calcium and the concentration of L. paracasei,” wrote the researchers.
    “This supports the hypothesis that calcium phosphate positively influences the colonization of L. paracasei in the human gut.” Source: Clinical Nutrition Published online ahead of print, doi: 10.1016/j.clnu.2011.09.013 “A combination of calcium phosphate and probiotics beneficially influences intestinal lactobacilli and cholesterol metabolism in humans” Authors: U. Trautvetter, B. Ditscheid, M. Kiehntopf, G. Jahreis
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    Probiotics may influence carbohydrate metabolism
    Probiotic bacteria consumed in a yogurt may not change the host’s gut populations, but they do influence carbohydrate metabolism by the resident microbes, according to an ‘elegant’ new study using identical twins and germ-free mice. — Probiotics in a yogurt were not found to colonize the gut microflora when studied in identical twins, but additional study in mice revealed that ingestion of the probiotic bacteria produced a change in many metabolic pathways, particularly those related to carbohydrate metabolism. — Researchers led by Dr Jeffrey Gordon at the Washington University School of Medicine, St. Louis, published their results yesterday in Science Translational Medicine. — In an accompanying perspective article the study was described as “elegant” by Jordan Bisanz and Gregor Reid from the Lawson Health Research Institute at the University of Western Ontario.
    Dr Gordon and his team have made a habit of advancing our understanding of gut microbe populations and their interactions with their hosts. In 2006, the St Louis-based researchers reported in Nature (Vol. 444, pp. 1022-1023, 1027-1031) that microbial populations in the gut are different between obese and lean people, and that when the obese people lost weight their microflora reverted back to that observed in a lean person, suggesting that obesity may have a microbial component. –Roadmap
    “One of the questions that this field is asking is what are the effects of these organisms on individuals,” said Dr Gordon in an audio podcast with Science Translational Medicine . —“Can we create a discovery pipeline where we can analyze their effects under highly controlled conditions – more controlled than we can achieve with human studies – and having interrogated those models, can we translate the information to humans to guide clinical trials, and gain a greater degree of insight about their effects?” — And that is what the researchers appear to have created. According to Bisanz and Reid, “a valuable roadmap has now been produced to guide future research on how exogenous organisms affect the host – and specifically its microbiome”. — In an email to NutraIngredients-USA, Prof Reid added: “The study is important as it tests a probiotic food in humans then investigates the mechanisms of action using a variety of state-of-the-art methods. The researchers then create a reduced microbiota in an animal and show that the effects of the probiotic can to some extent be mimicked.” —Study details — Dr Gordon and his team examined the potential of four months of consuming a commercial yogurt containing Bifidobacterium animalis subsp. lactis, two strains of Lactobacillus delbrueckii subsp. bulgaricus, Streptococcus thermophilis, and Lactococcus lactis subsp. cremoris, in seven pairs of female twins in their 20s and 30s. Dr Gordon has not named the product to avoid being seen as endorsing it. — The researchers also tested the effects of the yogurt in gnotobiotic mice, or mice that were completely germ-free except for the 15 specially introduced strains of bacteria that are present in the human gut. — Results showed that, in both mice and humans, the probiotic yogurt did not modify the composition of the gut microbial communities. — However, further analysis of using genome sequencing, and transcriptomic and metabolomic analyses, revealed a change in marked changes in numerous metabolic pathways, particularly those related to the processing of carbohydrates. — According to Bisanz and Reid, “a real strength of [Dr Gordon’s] study is that ingestion of a fermented milk product, essentially a commercial probiotic yogurt, was monitored by having the microbial transcriptional responses from the animal model acting as biomarkers for interrogation of the metatranscriptome data sets of the human twins. —“The apparent stability of the twins’ gut microbiota, despite a twice daily intake of the fermented milk product containing bifidobacteria and lactic acid-producing bacteria, demonstrates the remarkable ability of the host’s microbes to withstand the arrival of new strains of bacteria.”
    What next? — Dr Gordon and his co-workers note that his team’s experimental model could be used to identify biomarkers and other ‘mediators of the effects of existing or new probiotic strains’ The model may also help scientists identify potential new prebiotics that could also modify the metabolic effects of probiotic species. — Bisanz and Reid added that the “incredible precision and thoroughness of [Dr Gordon’s] study will not be easy to duplicate, but they have certainly laid a valuable pathway for others to follow.” Source: Science Translational Medicine 26 October 2011, Volume 3, Issue 106, 106ra106 “The Impact of a Consortium of Fermented Milk Strains on the Gut Microbiome of Gnotobiotic Mice and Monozygotic Twins” Authors: N.P. McNulty, T. Yatsunenko; A. Hsiao, et al.
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    Pineapple bromelain has anti-tumor properties superior to the chemo-agent 5-fluorouracil. – In vivo antitumoral activity of stem pineapple (Ananas comosus) bromelain.
    Abstract Source: Planta Med. 2007 Oct;73(13):1377-83. Epub 2007 Sep 24. PMID: 17893836
    Abstract Author(s): Roxana Báez, Miriam T Lopes, Carlos E Salas, Martha Hernández
    Abstract—–Stem bromelain (EC 3.4.22.32) is a major cysteine proteinase,[U1] isolated from pineapple ( Ananas comosus) stem. Its main medicinal use is recognized as digestive, in vaccine formulation, antitumoral and skin debrider for the treatment of burns. To verify the identity of the principle in stem fractions responsible for the antitumoral effect, we isolated bromelain to probe its pharmacological effects. The isolated bromelain was obtained from stems of adult pineapple plants by buffered aqueous extraction [U2]and cationic chromatography. The homogeneity of bromelain was confirmed by reverse phase HPLC, SDS-PAGE and N-terminal sequencing. The in vivo antitumoral/antileukemic activity was evaluated using the following panel of tumor lines: P-388 leukemia, sarcoma (S-37), Ehrlich ascitic tumor (EAT), Lewis lung carcinoma (LLC), MB-F10 melanoma and ADC-755 mammary adenocarcinoma. Intraperitoneal administration [U3]of bromelain (1, 12.5, 25 mg/kg), began 24 h after tumor cell inoculation in experiments in which 5-fluorouracil (5-FU, 20 mg/kg) was used as positive control. The antitumoral activity was assessed by the survival increase (% survival index) following various treatments. With the exception of MB-F10 melanoma, all other tumor-bearing animals had a significantly increased survival index after bromelain treatment. The largest increase ( approximately 318 %) was attained in mice bearing EAT ascites and receiving 12.5 mg/kg of bromelain. This antitumoral effect was superior to that of 5-FU, whose survival index was approximately 263 %, relative to the untreated control. Bromelain significantly reduced the number of lung metastasis induced by LLC transplantation, as observed with 5-FU. The antitumoral activity of bromelain against S-37 and EAT, which are tumor models sensitive to immune system mediators, and the unchanged tumor progression in the metastatic model suggests that the antimetastatic action results from a mechanism independent of the primary antitumoral effect.
    Pubmed Data : Planta Med. 2007 Oct;73(13):1377-83. Epub 2007 Sep 24. PMID: 17893836 Article Published Date : Oct 01, 2007
    Study Type : Animal Study
    Diseases : Cancer Metastasis : CK(230) : AC(120), Lung Cancer : CK(423) : AC(182)
    Pharmacological Actions : Anti-metastatic : CK(152) : AC(95)
    Additional Keywords : Drug: 5-flourouracil : CK(68) : AC(23), Food as Medicine : CK(15) : AC(6), Hall of Fame : CK(26) : AC(6), Superiority of Natural Substances versus Drugs : CK(776) : AC(172)
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    Plant Extraction
    The plant materials were cleaned of residual soil and air-dried at room temperature. Plants were ground to a fine powder using a laboratory mill and passed through a 24 mesh sieve to generate a homogeneous powder, stored at room temperature (22–23 °C), and protected from light until extraction.
    Methanolic extractions were conducted using 250 mg sample of each ground plant material, of the used parts (see Table (1), in 10 mL methanol (80%), at 37 °C for 3 h, in a shaking water bath. After cooling, the extract was centrifuged at 1500 g for 10 min, and the supernatant was recovered. The solvent was evaporated under vacuum at 40°C using a rotary evaporator. The solid residues were collected and stored in dry condition until analysis
    ( this is away to concentrate your remedy by allowing the materials to be in a solvent sealed and placed in 100degree water so that the materials will extract and become even more concentrated and then poured into a evaporator to remove all the alcohol and residue to all you have is a extract )
    Preparation of Extract for In Vitro Assay
    The tested extracts were initially dissolved in DMSO to give five different stock solutions with a concentration range of 0.625-10.0 mg/mL (0.625, 1.25, 2.5, 5.0 and 10mg/mL). Subsequently, 20 μL aliquot of each stock solution was used in the reaction mixture to give a final concentration range of 12.5- 200 μg/mL (12.5, 25, 25, 50 and 200 μg/mL).
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    Serrapeptase’s Uses
    Serrapeptase is known in several other names such as serralysin, serratiapeptase, serratia peptidase, serratio peptidase, or serrapeptidase and is derived from the microorganism called Serratiopeptidase which is found present in the intestines of silkworm which allows the emerging moth to dissolve its cocoon. Serrapeptase is produced by purification from culture of Serratia E-15 bacteria.
    It is an enzyme that eats or digests non-living tissue, blood clots, cysts, arterial plaque, inflammation, internal scar tissue as well as help with new external scars by either converting it into amino acids or excreted in the normal manner. Here are a few uses for Serrapeptase:
    As a natural solution to pain & inflammation–With Serrapeptase, chronic inflammation can be resolved or minimized in a natural and balanced way. Symptoms of inflammation disappear within 1 to 2 weeks but health practitioners normally recommend administration for up to 4 weeks to reassess the condition. –As a natural alternative to NSAIDs–Since the discovery of Serrapeptase and its wonderful healing properties with inflammation, it has become the favored choice compared to salicylates, ibuprofen and the more potent NSAIDs. Because Serrapeptase is naturally occurring, there fore no inhibitory effects on prostaglandins have been recorded and is devoid of gastrointestinal side effects.
    As an alternative to Warfarin—Warfarin is known for its blood thining properties that is why the proper dosage each time is sued and monitored. Serrapeptase also has blood thinning properties though not as potent as Warfarin. Many natural remedies and dietary improvements will thin the blood naturally that is why a doctor’s recommendation is always needed. Though that, blood thinning at certain levels is good as it makes the blood healthy if the blood is already too thick and the platelets are sticking together. Serrapeptase does not thin blood in an unhealthy way, rather it promotes healthy production of blood cells to stop chronic inflammation.
    As treatment for arterial blockage—Dr. Hans Neiper’s findings for serrepeptase is probably the main reason why serrapeptase is popular. Dr. Hans found that Serrapeptase has properties of treating arterial blockage in his coronary patients. It works by dissolving blood clots and shrinking varicose veins. Several of Dr. Hans’ patients who were scheduled for amputation recovered quickly through treatments of Serrapeptase. Serrapeptase is always known as a natural anti-inflammatory and as a strong protease that can dissolves the dead proteins that bind the plaque blocking the arteries. —As a natural inflammation treatment for: Arthritis, Ankylosing Spondylitis, Osteoporosis, Lupus, Diabetes, MS, Headaches and Migraines caused by inflammation –Lungs – Emphysema, Bronchitis, Pulmonary Tuberculosis, Bronchial Asthma, Cystic Fibrosis, Bronchiectasis etc ,Inflammatory bowel diseases such as Crohn’s, Colitis etc, Inflammation in joints or muscles e.g. Fibromyalgia, Repetitive strain injuries, Breast Engorgement, Fibrocystic Breast Disease, Cysts, Cardiovascular Disease, Arterial Disease, Angina, Blood clots, Varicose Veins, Eye, nose and throat problems from inflammation or blocked veins – ear infections, hayfever, swollen glands, laryngitis, rhinitis, sinusitis, runny nose,Sports Injuries, traumatic swelling, post operative swellings, leg ulcers Post operative healing -Enlarged Prostate
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    Serrapeptase Effects and Heals – can safely remove inflammation and dead tissue that causes pain, blocked arteries, varicose veins, lung problems and other common symptoms.–Serrapeptase, serrazyme, Serraplus+, serraplus+, inflammation, blocked arteries, varicose veins, dead tissue, lung problems, scar tissue, scars, Pain, Ankylosing Spondylitis, Arthritis, back problems, Diabetes, Leg Ulcers, Osteoporosis, Polymyalgia Rheumatica, Prostate Problems, Repetitive Strain (RSI) Carpal Tunnel, Rheumatoid Arthritis, Breast Engorgement, Cystitis, joints or muscles, Fibromyaligia, Fibrocystic Breast Disease, Headaches, Migranes, Inflammatory bowel diseases, Ulcerative Colitis, Crohn’s, IBS, Lupus, Lung, Chest, Asbestosis, Miners and Farmers Lung, Bronchietasis, Bronchial Asthma, Bronchitis, Coughs, Cystic Fibrosis, Emphysema, Pulmonary Tuberculosis, Eye Problems, Blocked veins, Multiple Sclerosis, MS, Neurological problems, Damaged Nerves, Ear, Nose, Throat problems, Chronic ear infections, Catarrhal Rhinopharyngitis, Hayfever, Sore Throat, Swollen Glands, Laryngitis, Runny nose, Rhinitis, Sinusitis problems, Trauma, Sports Injuries prevention.
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    Serrapeptase Reference
    l.. Kee WH. Tan SL, Lee V. Salmon YM. The treatment of breast engorgement with Serrapeptase (Danzen): a random ized double-blind controlled trial. Singapore Med J. 1989:30(1):48-54.
    2. M izukoshi, D. et al. A double-blind clinical study of serrapeptase in the treatment of chronic sinusitis. Igaku Ayrni 109:50-62.1979.
    3. Carratu, L. et al. Physio-chemical and rheological research on mucolytic activity of serrapeptase in chronic broncho-pneumopathies. Curr. Ther. Res. 28(6):937-951. 1980.
    4. Braga, P.C. et al. Effects of serrapeptase on muco-ciliary clearance in patients with chronic bronchitis. Curr. Ther. Res. 29(5):738-744,1981.
    5. Mazzonie, A. et al. Evaluation of serrapeptase in acute or chronic inflammation of otorhinolaryngology pathology: a multicentre, double-blind randomized trial versus placebo. J. int. Med. Res. 18(5):379-388,1990.
    6. Kakinumu, A. et al. Regression of fibrinolysis in scalded rats by administration of serrapeptase. Biochem. Pharmacol. 31:2861-2866,1982.
    7. Marly, M. Enzymotherapie anti-inflammatoire a l’aide de la serrapeptase: resultats cliniques en traumatologie et en ORL. C RTherapeut. 3:9-19,1985.
    8. Odagiri, J. et al. Clinical applications of serrapeptase in sinusitis. Med. Consult. New Remedy 6:201-209, 1979.
    9. Yamazaki, J. et al. Anti-inflammatory activity of TSP, a protease produced by a strain of Serratia. Folia Pharmacol. Japon. 6^302-314,1967.
    I0. Harad~, Y. Clinical efficacy of serrapeptase on buccal swelling after radical operation for chronic sinusitis. Igaku Ayumi 123:768-778.1982.
    1 I. Matsudo, A. et at. Effect of serrapeptase (Danzen) on inflammatory edema following operation for thyroid disease. Med. Consult. New Remedy 18:171-175, 1981.
    12. Fujitani, T. et al. Effect of anti-inflammatory agent on transfer of antibiotics to the maxillary sinus mucosa in chronic sinusitis. Otorhinolaryngol. Clin. North Am. 66:557-565. 1976.
    13. Tago. T. and Mitsui, S. Effects of serrapeptase in dissolution of sputum, especially in patients with bronchial asthma. Jap. Clin. Exp. Med. 49:222-228, 1972.
    14. Mazzonie, A. et al. Evaluation of serrapeptase in acute or chronic inflammation of otorhinolaryngology pathology: a multicentre, double-blind randomized trial versus placebo. J. int. Med. Res. 18(5):379-388,1990.
    15. Kase, Y. et al. A new method for evaluating mucolytic expectorant activity and its application. II. Application to two proteolytic enzymes, serrapeptase and seaprose. Arzneimittelforschung 32:374-378,1982.
    16. Marriott, C. Modification of the rheoloaical properties of mucus by drugs. Adv. Exp. Med. Biol. 144^75-84, 1982.
    17. Majima. Y. et al. Effects of orally administered drugs on dynamic viscoelasticity of human nasal mucus. Am. Rev. Respit. Dis. 141:79-83.1990.
    18. Miyata, K. Intestinal absorption of serrapeptase. J ApplBiochem. 1980:2:111-16.
    19. Aso T. et al. Breast engorgement and its treatment: Clinical effects of Danzen (serrapeptase) an anti-inflammatory enzyme preparation. The world of Obstetrics and Gynecology (Japanese). 1981:33:371-9.
    20. Esch PM, Gemgross H. Fabian A. Reduction of postoperative swelling. Objective measurement of swelling of the upper ankle joint in treatment with serrapeptase-a prospective study (German). FortschrMed. 1989; 107(4):67-8, 71-2.
    21. Majima Y, lnagaki M, Hirata K. Takeuchi K, M orishita A, Sakakura Y. The effect of an orally administered proteolytic enzyme on the elasticity and viscosity of nasal mucus. Arch Otorhinolaryngol. 1988;244(6):355-9.
    22. Selan L, Berlutti F, Passariello C. Comodi-Ballanti MR, Thaller MC. ?roteolytic enzymes: a new treatment strategy for prosthetic infections? Antimicrob Agents Cheroother. 1993; 37(12):2618-21.
    23. Koyama A, Mori J, Tokuda H, Waku M, Anno H, Katayama T, Murakami K, Komatsu H, Hirata M, Arai T, et al. Augmentation by serrapeptase of tissue permeation by cefotiam (Japanese). Jpn JAntibiot. 1986; 39(3):761-7
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    [U1]Cysteine Protein or amino
    [U2]The boiled them down
    [U3]The membrane that lines the walls of the abdomen and the pelvis (called the parietal peritoneum) and encloses the abdominal and pelvic organs (called the visceral peritoneum.)
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    Show Of The Week January 6 2012
    Artificial sweetener consumption is associated with urinary tract tumors.– Aceslfame K
    Effect of a Herbal-Leucine mix on the IL-1β-induced cartilage degradation and inflammatory gene expression in human chondrocytes.
    Anti-tumorigenic activity of five culinary and medicinal herbs grown under greenhouse conditions and their combination effects
    DHA used in infant formula products comes from genetically modified algae
    Antioxidant capacity of hesperidin from citrus peel using electron spin resonance and cytotoxic activity against human carcinoma cell lines.
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    Artificial sweetener consumption is associated with urinary tract tumors. – Aceslfame K
    Artificial sweetener consumption and urinary tract tumors in Cordoba, Argentina.
    Prev Med. 2008 Jul;47(1):136-9. Epub 2008 Apr 8. PMID: 18495230
    Abstract Author(s): M M Andreatta, S E Muñoz, M J Lantieri, A R Eynard, A Navarro Article Affiliation:
    Escuela de Nutrición, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Argentina. Abstract:
    OBJECTIVE: To determine the role of the habitual use of the most common artificial sweeteners (AS) in the development of urinary tract tumors (UTT) in Argentina. METHODS: Case-control study of 197 patients with histologically confirmed UTT of transitional varieties, and 397 controls with acute, non-neoplastic, and non-urinary tract diseases, admitted to the same hospitals in Córdoba (Argentina) between 1999 and 2006. All subjects were interviewed about their use of AS and their exposure to other known or suspected risk factors for UTT. RESULTS: Fifty-one UTT patients (26%) and 87 controls (22%) used AS. The risk of UTT was significantly increased in long-term (>or =10 years) AS users compared with none-AS users. The OR (95% CI) for long-term consumers was 2.18 (1.22-3.89) and for short-term users was 1.10 (0.61-2.00) after adjustment for age, gender, BMI, social status. and years of tobacco use. CONCLUSION: Regular use of AS for 10 years or more was positively associated with UTT.–Study Type : Human Study
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    Effect of a Herbal-Leucine mix on the IL-1β-induced cartilage degradation and inflammatory gene expression in human chondrocytes.
    BMC Complement Altern Med. 2011;11:66-Authors: Akhtar N, Miller MJ, Haqqi TM
    Abstract
    BACKGROUND: Conventional treatments for the articular diseases are often effective for symptom relief, but can also cause significant side effects and do not slow the progression of the disease. Several natural substances have been shown to be effective at relieving the symptoms of osteoarthritis (OA), and preliminary evidence suggests that some of these compounds may exert a favorable influence on the course of the disease. The objective of this study was to investigate the anti-inflammatory/chondroprotective potential of a Herbal and amino acid mixture containing extract of the Uncaria tomentosa, ( cats claw) Boswellia spp ( myrrh or frankinsense )., Lepidium meyenii( maca ) and L-Leucine on the IL-1β-induced production of nitric oxide (NO), glycosaminoglycan (GAG), matrix metalloproteinases (MMPs), aggrecan (ACAN) and type II collagen (COL2A1) in human OA chondrocytes and OA cartilage explants.—METHODS: Primary OA chondrocytes or OA cartilage explants were pretreated with Herbal-Leucine mixture (HLM, 1-10 μg/ml) and then stimulated with IL-1β (5 ng/ml). Effect of HLM on IL-1β-induced gene expression of iNOS, MMP-9, MMP-13, ACAN and COL2A1 was verified by real time-PCR. Estimation of NO and GAG release in culture supernatant was done using commercially available kits. –RESULTS: HLM tested in these in vitro studies was found to be an effective anti-inflammatory agent, as evidenced by strong inhibition of iNOS, MMP-9 and MMP-13 expression and NO production in IL-1β-stimulated OA chondrocytes (p < 0.05). Supporting these gene expression results, IL-1β-induced cartilage matrix breakdown, as evidenced by GAG release from cartilage explants, was also significantly blocked (p < 0.05). Moreover, in the presence of herbal-Leucine mixture (HLM) up-regulation of ACAN and COL2A1 expression in IL-1β-stimulated OA chondrocytes was also noted (p < 0.05). The inhibitory effects of HLM were mediated by inhibiting the activation of nuclear factor (NF)-kB in human OA chondrocytes in presence of IL-1β.
    CONCLUSION: Our data suggests that HLM could be chondroprotective and anti-inflammatory agent in arthritis, switching chondrocyte gene expression from catabolic direction towards anabolic and regenerative, and consequently this approach may be potentially useful as a new adjunct therapeutic/preventive agent for OA or injury recovery.—PMID: 21854562 [PubMed – indexed for MEDLINE]–You can do this several ways—anytime you increase nitric oxide reduce inflammation ( sodium phosphate) cayenne and tumeric and pineapple –you may see this sort of thing reverse—especially when adding gelatin and comfrey to your daily regimen—or utilizing anti catabolic ( stops the break down of muscle and tissue) substances or materials or foods.
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    Anti-tumorigenic activity of five culinary and medicinal herbs grown under greenhouse conditions and their combination effects.
    J Sci Food Agric. 2011 Aug 15;91(10):1849-54
    Authors: Yi W, Wetzstein HY
    Abstract
    BACKGROUND: Herbs and spices have been used as food preservatives, flavorings, and in traditional medicines for thousands of years. More and more scientific evidence supports the medicinal properties of culinary herbs. Colon cancer is the third leading cause of cancer death in the USA, and the fourth most common form of cancer worldwide. The objectives of this study were to evaluate the antitumor activity of five selected herbs grown under greenhouse conditions, and to study the potential synergistic effects among different herbal extract combinations.
    RESULTS: Thyme, rosemary, sage, spearmint, and peppermint extracts significantly inhibited SW-480 colon cancer cell growth, with sage extracts exhibiting the highest bioactivity, with 50% inhibition at 35.9 µg mL⁻¹, which was equivalent to 93.9 µg dried leaves mL⁻¹ of culture medium. Some mixtures of different herbal extracts had combination effects on cancer cell growth. The inhibitory effects of peppermint + sage combinations at a 1:1 ratio were significantly higher than rosemary + sage combinations at 1:1 ratio, although peppermint extracts showed lower inhibition than rosemary extracts.–CONCLUSION: Extracts from herb species (thyme, rosemary, sage, spearmint and peppermint) can significantly inhibit the growth of human colon cancer cells. Mixtures of herb extracts can have combination effects on cancer cell growth. The study suggests that these five herbs may have potential health benefits to suppress colon cancer.PMID: 21452174 [PubMed – indexed for MEDLINE]
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    DHA used in infant formula products comes from genetically modified algae
    One of the most vulnerable segments of the population — infants — are being affected as chemical giant Martek Biosciences uses cronyism to have its patented GMO products classified as organic. The National Organic Program is trying to correct this, but in the meantime the “organic” infant formula or baby food parents feed their children could contain industrial Frankenfood.
    History of Irresponsibility—-The story of how this state of affairs came about reveals much on how politics and profit can undermine food safety. Here’s a timeline on how the word “organic” is being undermined, creating a health threat for babies who are fed with formula.
    2002: Food manufacturers begin supplementing infant formula and baby food with synthetic forms of docosahexaenoic acid (DHA) and arachidonic acid (ARA). These polyunsaturated omega-3 and omega-6 fatty acids, naturally present in breast milk, are important components of the human brain and eyes. Although the form of DHA/ARA used in infant formulas is structurally incompatible with the form found in human milk, food manufacturers market their products with the claim that their formulas will make babies more intelligent.
    2006: In spite of the fact that its synthetic DHA/ARA is from laboratory-grown fermented algae and fungus through the use of hexane, a petroleum by-product and EPA-identified neurotoxin, Martek applies for organic status for its products. The USDA’s National Organic Program (NOP) tells Martek its synthetic DHA and ARA does not quality as organic. Martek attorney J. Friedman ignores the decision of NOP staff and contacts NOP director Barbara Robinson to have the decision reversed.
    2009: A front page Washington Post article, “Integrity of Federal ‘Organic’ Label Questioned” uncovers the Martek story. The article quotes Martek’s lawyer saying “I called Robinson up, I wrote an e-mail. It was a simple matter.”
    2002-2010: Parents and medical professionals observe reactions in babies fed with products containing Life’s DHA, the product name Martek gives its patented GMO version of naturally occurring fatty acids. The range of infant health problems includes difficulties breathing and gastrointestinal disorders. When affected babies are no longer fed the formula, the ailments disappear. Although Freedom of Information Act requests reveal hundreds of FDA adverse event reports, the FDA is slow to react.
    2011: FDA announces it will investigate claims that DHA/ARA infant formulas support brain and eye development. The National Organic Program is now trying to remedy its 2006 decision by asking Martek to formally ask permission of the NOP’s National Organic Standards Board to use its DHA and AHA in organic products.
    Products Containing this GMO
    In the meantime, Life’s DHA is being sold in many so-called organic brands which many consumers trust. Paying higher prices for products labeled as organic does not necessarily mean your family’s food does not include this particular Frankenfood. From Martek’s own website, here is a list of infant formulas containing their product which is both genetically modified and typically manufactured using a known toxin:
    Earth’s Best Organic Soy with DHA & ARA (Hain Celestial Group)
    Enfamil LIPIL (Mead Johnson Nutritionals)
    Enfamil Next Step (Mead Johnson)
    Isomil 2 Advance (Abbott Laboratories)
    Nestle Good Start Supreme with DHA & ARA (Nestle USA)
    Parent’s Choice Organic (Wal-Mart)
    Similac Advance (Abbott Nutrition)
    Ultra Bright Beginnings Lipids (PBM Products, LLC)
    There is also a long list of pre-natal supplements as well as vitamins and dietary supplements for infants, children and adults containing this product. A surprisingly wide range of foods and beverages use this GMO substance including Apple Bran Muffins sold at Starbucks; Farm Pride Omega-3 Eggs; Horizon Organic Milk; Kroger Active Lifestyle Premium Light OJ Beverage; Minute Maid Enhanced Pomegranate Blueberry Juice; Pediasure Children’s Beverage; Pompeian OlivExtra Plus and Silk Soymilk. The list of products containing this GMO is multinational, with products in many countries across the globe. If you want to check whether a supplement, food, or beverage you use contains Life’s DHA, the full list is here: http://www.lifesdha.com/Products-Co…
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    Antioxidant capacity of hesperidin from citrus peel using electron spin resonance and cytotoxic activity against human carcinoma cell lines.
    Pharm Biol. 2011 Mar;49(3):276-82—Authors: Al-Ashaal HA, El-Sheltawy ST
    Abstract
    CONTEXT: Hesperidin is a flavonoid that has various pharmacological activities including anti-inflammatory, antimicrobial and antiviral activities.
    OBJECTIVE: The aim of the study is the isolation of hesperidin from the peel of Citrus sinensis L. (Rutaceae), and the evaluation of its antioxidant capacity and cytotoxicity against different human carcinoma cell lines.
    MATERIALS AND METHODS: In the present work, hesperidin is identified and confirmed using chromatographic and spectral analysis. To correlate between hesperidin concentration and antioxidant capacity of peel extracts, extraction was carried out using 1% HCl-MeOH, MeOH, alkaline solution, the concentration of hesperidin determined qualitatively and quantitatively using high performance thin layer chromatography (HPTLC), high performance liquid chromatography (HPLC) analysis, in vitro antioxidant capacity of hesperidin and the extracts against free radical diphenylpicrylhydrazyl (DPPH•) performed using an electron spin resonance spectrophotometer (ESR). Cytotoxic assay against larynx, cervix, breast and liver carcinoma cell lines was performed.- RESULTS: Hesperidin was found to be moderately active as an antioxidant agent; its capacity reached 36%. In addition, the results revealed that hesperidin exhibited pronounced anticancer activity against the selected cell lines. IC₅₀ were 1.67, 3.33, 4.17, 4.58 µg/mL, respectively.– DISCUSSION AND CONCLUSION: Orange peels are considered to be a cheap source for hesperidin which may be used in the pharmaceutical industry as a natural chemopreventive agent. Hesperidin and orange peel extract could possess antioxidant properties with a wide range of therapeutic applications.–PMID: 21323480 [PubMed – indexed for MEDLINE]
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    Show Of The Week January 9 2012
     
    Delay Breastfeeding to “Improve” Vaccination?
    Senators Give Supplements a Lifeline
    When Overeating, Calories — Not Protein — Contribute to Increase in Body Fat
    Fountain of Youth in Bile- Longevity Molecule Identified
    Cancer-Killing Compound Spares Healthy Cells- Lithocholic acid
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    Delay Breastfeeding to “Improve” Vaccination?
    Over the course of the past few years, we have been gathering studies from the US National Library of Medicine on the adverse, unintended health effects of vaccination [1], in an attempt to offset the one-sided propaganda foisted upon the public, namely, that all vaccines are unequivocally “safe” and “effective,” a priori. —Along the way, we happened upon a 2010 study [2] published in the Journal of Pediatric Infections & Diseases which has been shared more than any other article on our database, and which suggests that breastfeeding should be delayed in order to prevent immune factors within breast milk from inactivating vaccine-associated antibody titer elevations and “vaccine potency.” The concluded the study with the following statement:–“INTERPRETATION: The lower immunogenicity and efficacy of rotavirus vaccines in poor developing countries could be explained, in part, by higher titers of IgA and neutralizing activity in breast milk consumed by their infants at the time of immunization that could effectively reduce the potency of the vaccine. Strategies to overcome this negative effect, such as delaying breast-feeding at the time of immunization, should be evaluated.”—It is not difficult to comprehend what caused the flurry of interest in this study. Readers were a the obviously disturbed by the suggestion that women in the underdeveloped world temporarily stop breast feeding (often the only source of infant nutrition) in order to increase the vaccine’s purported “efficacy.” Are we to assume that these breast milk deprived infants should consume formula* in the interim? And to what end? So that the vaccine can generate a temporary spike in antibody production, which is no measure of real-world effectiveness? —*Note: Infant formula has been linked to 48 adverse effects [3], including increased mortality.—First, it should be made clear that the term “efficacy,” when used in the context of a vaccine’s antibody-elevating effects, does not equate to effectiveness, i.e. whether or not a vaccine actually works in real life to protect against the infectious agent of concern.–It is this semantic trick (conflating and confusing “efficacy” with “effectiveness”) which convinces most of the “developed” world that vaccine research is “evidence-based” and focused on creating enhanced immunity, when in fact it is primarily a highly successful business enterprise dependent on defrauding its “customers” of both their money and health. The dangers of common vaccines [1] are so well known by “health experts,” and the manufacturers who produce, them that their risk (like nuclear power) is underwritten by world governments. The importance of this fact can not be overestimated or understated.———–Introducing foreign pathogenic DNA, chemicals, metals, preservatives, etc., into the body through a syringe will generate a response not unlike kicking a bee hive. The harder you kick that beehive, the greater will be the “efficacy” (i.e. elevated antibodies), but the actual affinity that these antibodies will have for the antigen (i.e. pathogen) of concern, can not be guaranteed; nor must the vaccine reseachers prove antibody-antigen affinity to receive FDA approval. –Also, valuable immune resources are wasted by generating “false flag” responses to threats which may not readily exist in the environment, e.g. there are over 200 forms of influenza A, B & C which can cause the symptoms associated with annual influenza A, so the seasonal trivalent flu vaccine only takes care of little more than 1% of the possible vectors of infection – and often at the price of distracting resources away from real threats and exhausting and/or damaging the entire immune apparatus. Truth be told, there is actually a shocking lack of evidence to support flu vaccines [4], in any age or population.—What’s worse, the vaccine response can “blow back” causing loss of self-tolerance and, via the resultant Th2 dominant immune system, the body can attack itself (auto-immunity). In the meantime, the first line of defense against infection (Th1) is compromised and this “front door” can be left wide open to unmet infectious challenges.—It is clear that one can create a synthetic immune response through vaccination, but it is not likely to result in enhanced immunity, insofar as real-world effectiveness is concerned, which is the only true judge of whether a vaccine is valuable or not. One might view the basic criteria used by vaccine researchers, namely, that generating elevated antibody titers proves the value of the vaccine, oppositely: proving the vaccine is causing harm to the developing infant by generating unnecessarily elevated antibodies by any means necessary, i.e. throwing the chemical and biological kitchen sink at the immune system, e.g. aluminum, phenol, diploid (aborted fetal) cells, peanut oil, pertactin, etc. –In the same way that secretory IgA from breast milk [5] deactivates a broad range of “natural” antigenic challenges for the infant, this breast milk derived, indispensable immune factor also deactivates the inherently disruptive and immunotoxic antibody-generating vaccine antigens and adjuvants. Rather than view this as the “enemy,” the reduction in antibodies that accompanies a well-nourished breastfed infant’s blood work, after the highly invasive and unnatural introduction of a vaccine, is a sign of health, not disease.—-This study struck a deep psychic chord out there. Images of phallic syringes stabbing away jealously at the symbolic breast of Nature come to mind, as the increasingly invasive ethos of modern medicine — always attempting to “improve on Nature” — drives us sick, mentally and physically. Can’t we just leave the timeless wisdom of mothering and nourishing that is woven into the mother-infant dyad alone?
    Additional Topics:
    Infant Formula: Risk Factor for 48 Diseases [3]
    Breast Feeding: Risk Reduction for 59 Diseases [6]
    Vaccination Research Database [1]
    Article: Infant Formula For Disaster [7]
    Vaccine researchers have suggested delaying breastfeeding to “improve” vaccine efficacy. Images of phallic syringes stabbing away jealously at the symbolic breast of Nature come to mind, as the increasingly invasive ethos of modern medicine — always attempting to “improve on Nature” — drives us sick, mentally and physically. Can’t we just leave the timeless wisdom of mothering and nourishing that is woven into the mother-infant dyad alone?
    Source URL: http://www.greenmedinfo.com/blog/researchers-delay-breastfeeding-improve-vaccination
    Links:
    [1] http://www.greenmedinfo.com/page/vaccine-research
    [2] http://www.greenmedinfo.com/article/vaccination-proponents-have-suggested-breastfeeding-should-be-delayed-order-prevent-immune-f
    [3] http://www.greenmedinfo.com/toxic-ingredient/infant-formula
    [4] http://www.greenmedinfo.com/blog/shocking-lack-evidence-supporting-flu-vaccines
    [5] http://www.greenmedinfo.com/substance/breast-milk
    [6] http://www.greenmedinfo.com/therapeutic-action/breastfeeding
    [7] http://www.sayerji.com/published-writings/infant-formula-for-disaster
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    Senators Give Supplements a Lifeline
    Will it be enough to rein in FDA’s outrageous power grab?
    ANH-USA, together with a number of supplement trade organizations, went to Capitol Hill to plead our case about the FDA’s profoundly flawed NDI (new supplement) draft guidance in the offices of two powerful senators and longtime friends of natural health, Sen. Tom Harkin (D-IA) and Sen. Orrin Hatch (R-UT). Our visit was preceded by all the letters you have been sending to Congress, which have immeasurably increased the visibility of this issue. As you know, if this draft guidance stands, it would allow FDA to arbitrarily deny the sale of any supplement created (or modified) in the past seventeen years [1]. Immediately after this meeting, Sens. Harkin and Hatch wrote to FDA Commissioner Margaret Hamburg and formally asked the FDA to withdraw its guidance document.——-The senators urged FDA to begin work on a new draft that provides needed clarification on what constitutes a New Dietary Ingredient (NDI)—but, in their words, does not undermine Congress’s desire to provide consumers with access to safe, affordable dietary supplement products. Exactly!——–These senators were uniquely qualified to make such a request, since they were the principal authors of DSHEA, the Dietary Supplement Health and Education Act of 1994. “When Congress included language in the Food Safety Modernization Act (FSMA) directing FDA to clarify when a dietary supplement ingredient is a new dietary ingredient, the expectation was that the guidance would be consistent with DSHEA,” they write. “Unfortunately, the draft guidance serves to undermine DSHEA in a number of important respects.”
    They go on to outline the various arguments that we have been making in these pages for some time:
    The requirement for a manufacturer to submit an NDI notification for every dietary supplement containing an NDI is directly contrary to the language of DSHEA, which requires notification only of the intent to use an NDI;
    This new requirement is burdensome and would impose substantial additional costs on manufacturers, would not provide additional safety benefits, and would undermine access to the safe, affordable nutritional supplements that DSHEA was designed to ensure;
    The NDI guidance’s assertion that synthetic copies of ingredients can never be a dietary ingredient is without any statutory basis, and is contrary to longstanding FDA policy; and
    This guidance is contrary to Congressional intent by grandfathering in only ingredients that were marketed before the enactment of DSHEA—such an argument is particularly specious since “the term dietary supplement wasn’t even defined prior to DSHEA”!
    The senators requested that FDA meet with interested parties to work through all of the issues raised in our and others’ comments. Fortunately, FDA can’t just ignore the senators’ request, because the agency is required to work within legislative intent. Otherwise they would be creating new law—which legally they cannot do. This is one of the arguments we have been making all along—that FDA is in fact making new law with this draft guidance, and now Congress is calling them on it!—-We would like to thank Senators Harkin and Hatch for being such stalwart champions of natural health, and for their leadership in this battle to prevent the FDA from usurping powers that they are not legally entitled to. We also want to thank every one of you for contacting Congress and the FDA and being such a vital part of this process.—We aren’t out of the woods yet—we’ll have another update soon with additional action items for you. The time may come for more specific legislative action, and we may find ourselves battling FDA in the courts as well. That’s why your continued support and activism is so terribly important. Together we can win this one, preserve your access to supplements, and keep supplements from costing as much as drugs.
    Article printed from Welcome to the Alliance for Natural Health – USA: http://www.anh-usa.org
    URL to article: http://www.anh-usa.org/senators-give-supplements-a-lifeline/
    URLs in this post:
    [1] it would allow FDA to arbitrarily deny the sale of any supplement created (or modified) in the past seventeen years: http://www.anh-usa.org../../../../../fda-guidelines-a-perversion-of-congressional-intent/
     
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    When Overeating, Calories — Not Protein — Contribute to Increase in Body Fat
    ScienceDaily (Jan. 3, 2012) — In a study conducted among 25 healthy individuals living in a controlled setting who were randomized to overconsumption of different levels of protein diets, those consuming the low-protein diet had less weight gain compared to those consuming normal and high protein diets, and calories alone, and not protein appeared to contribute to an increase in body fat, according to a study in the January 4 issue of JAMA. The researchers also found that protein did contribute to changes in energy expenditure and lean body mass.—–“Obesity has become a major public health concern with more than 60 percent of adults in the United States categorized as overweight and more than 30 percent as obese,” according to background information in the article. The role of diet composition in response to overeating and energy dissipation is unclear.–George A. Bray, M.D., of the Pennington Biomedical Research Center, Baton Rouge, La., and colleagues conducted a study to determine whether the level of dietary protein differentially affected body composition, weight gain, or energy expenditure under tightly controlled conditions. The randomized controlled trial included 25 U.S. healthy, weight-stable male and female volunteers, ages 18 to 35 years, with a body mass index between 19 and 30. The first participant was admitted to the inpatient metabolic unit in June 2005 and the last in October 2007. After consuming a weight-stabilizing diet for 13 to 25 days, participants were randomized to receive diets containing 5 percent of energy from protein (low protein), 15 percent (normal protein), or 25 percent (high protein), which they were overfed during the last 8 weeks of their 10- to 12-week stay in the inpatient metabolic unit. Compared with energy intake during the weight stabilization period, the protein diets provided approximately 40 percent more energy intake, which corresponds to 954 calories a day.—All participants in the study gained weight and there were no differences by sex. The rate of weight gain in the low protein diet group was significantly less than in the other 2 groups (6.97 lbs. [3.16 kg] vs. 13.3 lbs [6.05 kg] for the normal protein diet group and 14.4 lbs [6.51 kg] in the high protein diet group).–“Body fat increased similarly in all 3 protein diet groups and represented 50 percent to more than 90 percent of the excess stored calories. Resting energy expenditure, total energy expenditure, and body protein did not increase during overfeeding with the low protein diet,” the authors write.-Lean body mass (body protein) decreased during the overeating period by 1.5 lbs. (0.70 kg) in the low protein diet group compared with a gain of 6.3 lbs. (2.87 kg) in the normal protein diet group and 7 lbs. (3.18 kg) in the high protein diet group. Resting energy expenditure (normal protein diet: 160 calories/day; high protein diet: 227 calories/day) increased significantly with the normal and high protein diets.-“In summary, weight gain when eating a low protein diet (5 percent of energy from protein) was blunted compared with weight gain when eating a normal protein diet (15 percent of energy from protein) with the same number of extra calories. Calories alone, however, contributed to the increase in body fat. In contrast, protein contributed to the changes in energy expenditure and lean body mass, but not to the increase in body fat,” the researchers write. “The key finding of this study is that calories are more important than protein while consuming excess amounts of energy with respect to increases in body fat.”
    Editorial: Overeating and Overweight — Extra Calories Increase Fat Mass While Protein Increases Lean Mass—-In an accompanying editorial, Zhaoping Li, M.D., Ph.D., and David Heber, M.D., Ph.D., of the University of California, Los Angeles, write that the results of this study “informs primary care physicians and policy makers about the benefits of protein in weight management.” “The results suggest that overeating low protein diets may increase fat deposition leading to loss of lean body mass despite lesser increases in body weight. Policy makers and primary care physicians need to understand the role of the Western diet in promoting overweight and obesity. Because this diet increases the risks of overnutrition through fat deposition beyond that detected by body mass index, the method used to assess the current obesity epidemic and the magnitude of the obesity epidemic may have been underestimated. Clinicians should consider assessing a patient’s overall fatness rather than simply measuring body weight or body mass index and concentrate on the potential complications of excess fat accumulation. The goals for obesity treatment should involve fat reduction rather than simply weight loss, along with a better understanding of nutrition science.” Story Source-The above story is reprinted from materials provided by JAMA and Archives Journals.
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    Cancer-Killing Compound Spares Healthy Cells- Lithocholic acid
    ScienceDaily (Jan. 4, 2012) — Lithocholic acid (LCA), naturally produced in the liver during digestion, has been seriously underestimated. A study published in the journal Oncotarget shows that LCA can kill several types of cancer cells, such as those found in some brain tumors and breast cancer.The research team, led by Concordia University, included scientists from McGill University and the Jewish General Hospital’s Lady Davis Institute in Montreal as well as the University of Saskatchewan.–Previous research from this same team showed LCA also extends the lifespan of aging yeast. This time, the team found LCA to be very selective in killing cancer cells while leaving normal cells unscathed. This could signal a huge improvement over the baby-with-the-bathwater drugs used in chemotherapy.–“LCA doesn’t just kill individual cancer cells. It could also prevent the entire tumor from growing,” says senior author Vladimir Titorenko, a professor in the Department of Biology and Concordia University Research Chair in Genomics, Cell Biology and Aging.–What’s more, LCA prevents tumors from releasing substances that cause neighboring cancer cells to grow and proliferate. Titorenko says LCA is the only compound that targets cancer cells, which could translate into tumor-halting power.–This is important for preventing cancer cells from spreading to other parts of the body,” he says, noting that unlike other anti-aging compounds, LCA stops cancer cell growth yet lets normal cells continue to grow.–A wide effect on different types of cancers –The next step for the research team will be to test LCA’s effect on different cancers in mice models. Titorenko expects that LCA will also kill cancer cells in those experiments and lead to human clinical trials. “Our study found that LCA kills not only tumors (neuroblastomas), but also human breast cancer cells,” says Titorenko. “This shows that it has a wide effect on different types of cancers.”–Titorenko emphasizes that unlike drugs used in chemotherapy, LCA is a natural compound that is already present in our bodies. Studies have shown that LCA can be safely administered to mice by adding it to their food. So why is LCA so deadly for cancer cells? Titorenko speculates that cancer cells have more sensors for LCA, which makes them more sensitive to the compound than normal cells.—LCA sensors send signals to mitochondria — the powerhouses of all cells. It seems that when these signals are too strong, mitochondria self-destruct and bring the cell down with them. Simply put, Titorenko and his colleagues engaged in cancer cell sabotage by targeting a weakness to LCA.–This study was supported by the Canadian Institutes of Health Research, the Natural Sciences and Engineering Research Council of Canada and the Concordia University Research Chair program.-Story Source-The above story is reprinted from materials provided by Concordia University. -Journal Reference–Goldberg AA, Beach A, Davies GF, Harkness TA, Leblanc A, Titorenko VI. Lithocholic bile acid selectively kills neuroblastoma cells, while sparing normal neuronal cells.. Oncotarget, 2011 Oct;2(10):761-82 [link]

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    Fountain of Youth in Bile- Longevity Molecule Identified
    (Bile Acids are Organic Acids that are a constituent of Bile – they occur primarily as Salts. Chemically, Bile Acids are classified as Steroids)
    Cholesterol is excreted from the body by Bile Acids. Bile Acids are the body’s only significant mechanism for the elimination of excess Cholesterol from the body. Bile Acids solubilize Cholesterol in the Bile, preventing the precipitation of Cholesterol in the Gallbladder.
    Bile Acids facilitate the digestion of Triglycerides from dietary Fats. Bile Acids function as emulsifying agents that render the Fatty Acids from dietary Triglycerides accessible to Pancreatic Lipase.
    Bile Acids facilitate the intestinal absorption of Fat-Soluble Vitamins.
    Immune System-Bile Acids may suppress Helicobacter pylori.
    New research has identified the role of a bile acid, called lithocholic acid, in extending the lifespan of normally aging yeast—ScienceDaily (Sep. 15, 2010) — The human quest for longer life may be one step closer, thanks to research from Concordia University. Published in the journal Aging, a new study is the first to identify the role of a bile acid, called lithocholic acid (LCA), in extending the lifespan of normally aging yeast. The findings may have significant implications for human longevity and health, as yeast share some common elements with people. “Although we found that LCA greatly extends yeast longevity, yeast do not synthesize this or any other bile acid found in mammals,” says senior author Vladimir Titorenko, Concordia University Research Chair in Genomics, Cell Biology and Aging and a professor in the Department of Biology. “It may be that yeast have evolved to sense bile acids as mildly toxic molecules and respond by undergoing life-extending changes. It is conceivable that the life-extending potential of LCA may be relevant to humans as well.”
    Over 19,000 small molecules screened
    Titorenko and colleagues screened more than 19,000 small molecules to test their ability to extend yeast-lifespan. Under both normal and stressed conditions, LCA had a major impact.–“Our findings imply that LCA extends longevity by targeting two different mechanisms,” says first author Alexander Goldberg, a Concordia doctoral student. “The first takes place regardless of the number of calories and involves the day-to-day or housekeeping proteins. The second system occurs during calorie-restriction and involves stressor proteins.”—“Regardless of their triggers both of these mechanisms work to suppress the pro-aging process,” he continues.– Bile acids may be beneficial to health—“Although we have an overall idea how LCA works to extend longevity in yeast, we still need to determine if this is the case for other species,” says Titorenko. “We do know from previous studies, however, that bile acids are beneficial to health and longevity. For example, they have shown to accumulate in the serum of long living mice and play a role in improving rodent liver and pancreatic function.”–“This leads us to believe that bile acids have potential as pharmaceutical agents for the treatment of diabetes, obesity and various metabolic disorders, all of which are age-related,” continues Titorenko. “They may indeed offer hope for a healthy aging life.”—This study was funded by the Canadian Institutes of Health Research, the Natural Sciences and Engineering Research Council of Canada, the Canada Foundation for Innovation and the Concordia University Chair Fund.—Story Source-The above story is reprinted from materials provided by Concordia University. –Journal References-Alexander A. Goldberg, Vincent R. Richard, Pavlo Kyryakov, Simon D. Bourque, Adam Beach, Michelle T. Burstein, Anastasia Glebov, Olivia Koupaki, Tatiana Boukh‐Viner, Christopher Gregg, Mylène Juneau, Ann M. English, Vladimir I. Titorenko and David Y. Thomas. Chemical genetic screen identifies lithocholic acid as an anti‐aging compound that extends yeast chronological life span in a TOR independent manner, by modulating housekeeping longevity assurance processes. Aging, 2010; 2 (7): 393 [link]–Alexander A. Goldberg, Pavlo Kyryakov, Simon D. Bourque and Vladimir I. Titorenko. Xenohormetic, hormetic and cytostatic selective forces driving longevity at the ecosystemic level. Aging, 2010; 2 (8): 461-470 [link]
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    Show Of The Week January 13 2012
     
    Taurine increases bile acid pool size and reduces bile saturation index In the hamster
    Dietary Taurine Enhances Cholesterol Degradation and Reduces Serum and Liver Cholesterol
    High Dietary Taurine Reduces Apoptosis and Atherosclerosis in the Left Main Coronary Artery
    Leaked– US to Start ‘Trade Wars’ with Nations Opposed to Monsanto, GMO Crops
    How to Oxygenate yourself
    Hydrogen Peroxide Benefits and Data
     
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    Taurine increases bile acid pool size and reduces bile saturation index In the hamster
    S Bellentani,
    M Pecorari,
    P Cordoma,
    P Marchegiano,
    F Manenti,
    E Bosisio,
    E De Fabiani and
    G Galli
    + Author Affiliations
    Chair of Gastroenterology, University of Modena, Italy.
    Abstract
    There is evidence that increased availability of taurine enhances the proportion of taurine-conjugated bile acids in bile. To explore the possibility that taurine treatment could also influence hepatic cholesterol and bile acid metabolism, we fed female hamsters for 1 week and measured both the biliary lipid content and the microsomal level of the rate-limiting enzymes of cholesterol and bile acid synthesis. In these animals the cholesterol 7 alpha-hydroxylase activity was significantly greater in respect to controls (P less than 0.05). The total HMG-CoA reductase activity, as well as that of the active form, was similarly increased. The stimulation of 7 alpha-hydroxycholesterol synthesis was associated with an expansion of the bile acid pool size in taurine-fed animals. Taurine feeding was observed to induce an increase in bile flow as well as in the rate of excretion of bile acids, whereas the secretion rate of cholesterol in bile was decreased. As a consequence, the saturation index was significantly lower in taurine-fed animals (P less than 0.05). The possible mechanisms through which taurine exhibits the modification of the enzyme activities and of the biliary lipid composition are discussed.
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    Dietary Taurine Enhances Cholesterol Degradation and Reduces Serum and Liver Cholesterol Concentrations in Rats Fed a High-Cholesterol Diet1
    Hidehiko Yokogoshi*2, Hideki Mochizuki*, Ken Nanami*, Yuko Hida*, Fuyuko Miyachi† and Hiroaki Oda†
    ; * ; School of Food and Nutritional Sciences, The University of Shizuoka, Shizuoka 422-8526, Japan and; † ; Department of Applied Biological Sciences, Nagoya University, Nagoya 464-8601, Japan
    2To whom correspondence and reprint requests should be addressed.
    The effect of taurine on hypercholesterolemia induced by feeding a high-cholesterol (HC) diet (10g/kg) to rats was examined. When various amounts of taurine (0.25, 0.5, 1, 2.5, 5, 10, 20, 30, 40 or 50 g/kg diet) were supplemented to HC for 2 wk, serum total cholesterol gradually and significantly decreased in a dose-dependent manner and normalized at the dose of 10 g taurine/kg, compared with the control (cholesterol free) diet group. By contrast, serum HDL-cholesterol was elevated by taurine supplementation. The HC diet caused a significant decrease in the concentration of taurine in serum, liver and heart compared to that in the control group, and the effective dose of supplemental taurine to improve its reduction was 2.5 g/kg diet. In the hypercholesterolemic rats fed the HC diet, the excretion of fecal bile acids and hepatic cholesterol 7 α-hydroxylase (CYP7A1) activity and its mRNA level increased significantly, and the supplementation of taurine further enhanced these indexes, indicating an increase in cholesterol degradation. The abundance of mRNA for Apo A-I, one of the main components of HDL, was reduced by HC and recovered by taurine supplementation. Agarose gel electrophoresis revealed that, in hypercholesterolemic rats fed the HC diet, the serum level of the heavier VLDL increased significantly, but taurine repressed this increase and normalized this pattern. Significant correlations were observed between the time- and dose-dependent increases of CYP7A1 gene expression and the decrease of blood cholesterol concentration in rats fed the HC diet supplemented with taurine (time, r = -0.538, P < 0.01, n = 32; dose, r = -0.738, P < 0.001, n = 20). These results suggest that the hypocholesterolemic effects of taurine observed in the hypocholesterolemic rats fed the HC diet were mainly due to the enhancement of cholesterol degradation and the excretion of bile acid.
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    High Dietary Taurine Reduces Apoptosis and Atherosclerosis in the Left Main Coronary Artery—-Association With Reduced CCAAT/Enhancer Binding Protein Homologous Protein and Total Plasma Homocysteine but not Lipidemia
    Anthony Zulli,
    Eza Lau,
    Bagus P.P. Wijaya,
    Xin Jin,
    Komang Sutarga,
    Grace D. Schwartz,
    Jonathon Learmont,
    Peter J. Wookey,
    Angelo Zinellu,
    Ciriaco Carru,
    David L. Hare
    + Author Affiliations
    From the Departments of Cardiology (A.Z., E.L., B.P.P.W., X.J., K.S., G.D.S., J.L., P.J.W., D.L.H.) and Medicine (A.Z., D.L.H.), University of Melbourne, Austin Health, Heidelberg, Australia; and the Department of Biomedical Sciences (A.Z., C.C.), University of Sassari Viale S Pietro, Sassari, Italy.
    Correspondence to Anthony Zulli, Vascular Laboratory, Department of Cardiology, Austin Health, Heidelberg, Australia. E-mail [email protected]
    Abstract
    We sought to determine whether taurine could specifically protect against coronary artery disease during an atherogenic diet and whether taurine affects the lipid profile, metabolites of methionine, and endothelial atherogenic systems. Rabbits were fed one of the following diets for 4 weeks: (1) control diet; (2) 0.5% cholesterol+1.0% methionine; or (3) 0.5% cholesterol+1.0% methionine+2.5% taurine. Endothelial function was examined, and the left main coronary artery atherosclerosis was quantified by stereology and semiquantitative immunohistochemistry to determine the endothelial expression of proteins related to the NO, renin-angiotensin, endoplasmic reticulum, and oxidative stress systems, as well as apoptosis. Taurine normalized hyperhomocysteinemia (P<0.05) and significantly reduced hypermethioninemia (P<0.05) but not lipidemia. The intima:media ratio was reduced by 28% (P=0.034), and atherosclerosis was reduced by 64% (P=0.012) and endothelial cell apoptosis by 30% (P<0.01). Endothelial cell CCAAT/enhancer binding protein homologous protein was normalized (P<0.05). Taurine failed to improve hyperlipidemia, endothelial function, or endothelial proteins related to the NO, renin-angiotensin, and oxidative stress systems. Taurine reduces left main coronary artery wall pathology associated with decreased plasma total homocysteine, methionine, apoptosis, and normalization of CCAAT/enhancer binding protein homologous protein. These results elucidate the antiapoptotic and antiatherogenic properties of taurine, possibly via normalization of endoplasmic reticulum stress.
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    Leaked– US to Start ‘Trade Wars’ with Nations Opposed to Monsanto, GMO Crops
    The United States is threatening nations who oppose Monsanto’s genetically modified (GM) crops with military-style trade wars, according to information obtained and released by the organization WikiLeaks. Nations like France, which have moved to ban one of Monsanto’s GM corn varieties, were requested to be ‘penalized’ by the United States for opposing Monsanto and genetically modified foods. The information reveals just how deep Monsanto’s roots have penetrated key positions within the United States government, with the cables reporting that many U.S. diplomats work directly for Monsanto. The WikiLeaks cable reveals that in late 2007, the United States ambassador to France and business partner to George W. Bush, Craig Stapleton, requested that the European Union along with particular nations that did not support GMO crops be penalized. Stapleton, who co-owned the Dallas/Fort Worth-based Texas Rangers baseball team with Bush in the 1990s, stated–“Country team Paris recommends that we calibrate a target retaliation list that causes some pain across the EU since this is a collective responsibility, but that also focuses in part on the worst culprits. The list should be measured rather than vicious and must be sustainable over the long term, since we should not expect an early victory. Moving to retaliation will make clear that the current path has real costs to EU interests and could help strengthen European pro-biotech voices.”
    The Leaked Political Agenda Behind Monsanto’s GMO Crops
    The ambassador plainly calls for ‘target retaliation’ against nations who are against using Monsanto’s genetically modified corn, admittedly linked to organ damage and environmental devastation. Amazingly, this is not an isolated case. In similar newly released cables, United States diplomats are found to have pushed GMO crops as a strategic government and commercial imperative. Furthermore, the U.S. specifically targeted advisers to the pope, due to the fact that many Catholic bishops and figureheads have openly denounced GMO crops. In fact, the Vatican has openly declared Monsanto’s GMO crops as a ‘new form of slavery’.[U1] “A Martino deputy told us recently that the cardinal had co-operated with embassy Vatican on biotech over the past two years in part to compensate for his vocal disapproval of the Iraq war and its aftermath – to keep relations with the USG [US government] smooth. According to our source, Martino no longer feels the need to take this approach,” says the cable.—Perhaps the most shocking piece of information exposed by the cables is the fact that these U.S. diplomats are actually working directly for biotech corporations like Monsanto. The cables also highlight the relationship between the U.S. and Spain in their conquest to persuade other nations to allow for the expansion of GMO crops. Not only did the Spanish government secretly correspond with the U.S. government on the subject, but the U.S. government actually knew beforehand how Spain would vote before the Spanish biotech commission reported their decision regarding GMO crops. The cable states–“In response to recent urgent requests by [Spanish rural affairs ministry] state secretary Josep Puxeu and Monsanto, post requests renewed US government support of Spain’s science-based agricultural biotechnology position through high-level US government intervention.”—-Monsanto has undoubtedly infiltrated the United States government in order to push their health-endangering agenda, and this has been known long before the release of these WikiLeaks cables. The U.S. is the only place where Monsanto’s synthetic hormone Posilac is still used in roughly 1/3 of all cows, with 27 nations banning the substance over legitimate health concerns. Despite Monsanto’s best attempts at incognito political corruption, nothing can stop the grassroots anti-Monsanto movement that is taking over cities and nations alike
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    How to Oxygenate yourself
    Oxygenate—when you see heavy dosing of chem. Trails you may want to use “ Rocket Fuel” as some call it in science or Hydrogen Peroxide—if you have food grade—take 1-3 drops in a 1 ounce container—add distilled water and then attach a mister or a spray nozzle—and every so often give your self a pump this will release or increase Oxygen into the blood stream and take a load off the heart—and increase oxygen circulation throughout the body—
    When doing this as well Increase Vitamin C intake ( 5 grams plus) to offset any prooxidant effect of the H2O2
    ORRR got to a dollar store and get a Peroxide without stabilzers—and add the whole thing to a one ounce bottle and add a mister to it and apply as been mentioned in the above paragraph—this will again offset any potential issue that may occur as a lack of Oxygen
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    Hydrogen Peroxide Benefits and Data
    Pure Hydrogen Peroxide, discovered by a French chemist in 1818 was utilized extensively from the early 19th century until the early 20th Century as a treatment of various illnesses such as; asthma, cholera, syphilis, typhoid fever, tuberculosis, ulcers and pertussis. Food Grade Hydrogen Peroxide is approved by the United States Department of Agriculture as it contains no harmful additives.
    The use of Hydrogen Peroxide Treatment lost a great deal of its appeal with the introduction of the pharmaceutical industry in the 20th Century. With the increased knowledge of several of the side effects produced by taking today’s prescribed medicines, a lot of individuals are reverting back to the use of the older, conventional cures including Hydrogen Peroxide Treatment, also called Oxygen Therapy.
    Hydrogen Peroxide was utilized following the First World War to fight a pneumonia pandemic. It was, and still is, used extensively to treat emphysema and congestive lung problems. The main benefit is due to its ability to increment the oxygen content of blood and body tissue which increases blood flow and raises body temperature.
    Some of the medical uses of Food Grade Hydrogen Peroxide contain:
    Cuts, Scrapes and Open Sores -This is the old conventional treatment for open cuts and sores. The procedure consists of applying Hydrogen Peroxide to kill any infection.
    Acne – Applied with a cotton swob it will dehydrate the acne. A moisturizer ought to be applied afterwards to restore some of the natural moisture of the skin as the Hydrogen Peroxide will dry the area encompassing the acne.
    Mouthwash – A mild solution may be used as a mouthwash. This will kill bacteria that causes bad breath as well as help prevent Periodontal disease. Simultaneously it will whiten your teeth.
    Take away Ear Wax – A weak solution put in your ear will aid in the removal of set ear wax.
    Athletes Feet – You could use a spray bottle to apply to affected areas of the feet. This will kill off the fungus causing the athletes feet.
    Colds, Flu – Gargling a weak solution will kill off the germs causing these illnesses.
    Some Non-medical, family uses, include:
    Stain Remover – Amazing for removing blood stains.
    Sanitizer – Utilize it in the kitchen and bathroom to sanitize and clean all surfaces.
    Wash Vegetables – Vegetables are sprayed with all types of insecticides and additives to keep them fresh. Rinsing them off with a solution of Hydrogen Peroxide will kill off these harmful additives.
    Water Plants – Utilized to provide extra oxygen to the soil. Numerous farmers now spray a weak solution on their crops to remove harmful bacteria and act as a natural insecticide.
    Treat Fungus – Wash moldy places with Hydrogen Peroxide.
    Hydrogen Peroxide is likely one of the best and least expensive products on the market nowadays that can be utilized in a lot of areas. Everybody should have a bottle on hand at all times and utilize it wherever harmful bacteria is present.
    Utilize it with care and utilize it often
    Read more: http://www.articlesbase.com/health-articles/benefits-and-many-uses-of-food-grade-hydrogen-peroxide-4201698.html#ixzz1KriOiqjM
    Under Creative Commons License: Attribution
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    [U1]The Irony Here is that Own Monsanto—so this is a smoke screen to distance themselves as to save Face among there 1 billion catholics—if they knew that there own religion was forming a genocide on the membership they would be outraged—this would disassociate them from the institution
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    Show of the Week January 16 2012
     
    Does Sugar Feed Cancer?
    Cancer Cells Feed On Sugar-Free Diet
    Statins linked with small diabetes risk
    Rare ‘supersoldier’ ants created in Canadian lab
    These Substances may Enhance Hair Growth -if Hair Follicles are still Alive
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    Does Sugar Feed Cancer?
    ScienceDaily (Aug. 17, 2009) — Researchers at Huntsman Cancer Institute at the University of Utah have uncovered new information on the notion that sugar “feeds” tumors. The findings may also have implications for other diseases such as diabetes. The research is published in the journal Proceedings of the National Academy of Sciences.–“It’s been known since 1923 that tumor cells use a lot more glucose than normal cells. Our research helps show how this process takes place, and how it might be stopped to control tumor growth,” says Don Ayer, Ph.D., a Huntsman Cancer Institute investigator and professor in the Department of Oncological Sciences at the University of Utah.-During both normal and cancerous cell growth, a cellular process takes place that involves both glucose (sugar) and glutamine (an amino acid). Glucose and glutamine are both essential for cell growth,[U1] and it was long assumed they operated independently, but Ayer’s research shows they are inter-dependent. He discovered that by restricting glutamine availability, glucose utilization is also stopped. “Essentially, if you don’t have glutamine, the cell is short circuited due to a lack of glucose, which halts the growth of the tumor cell” Ayer says.–The research, spearheaded by Mohan Kaadige, Ph.D., a postdoctoral fellow in Ayer’s lab, focused on MondoA, a protein that is responsible for turning genes on and off. In the presence of glutamine, MondoA blocks the expression of a gene called TXNIP. TXNIP is thought to be a tumor suppressor, but when it’s blocked by MondoA , it allows cells to take up glucose, which in turn drives tumor growth. Ayer’s research could lead to new drugs that would target glutamine utilization, or target MondoA or TXNIP.–Ayer says the next step in his research is to develop animal models to test his ideas about how MondoA and TXNIP control cell growth. “If we can understand that, we can break the cycle of glucose utilization which could be beneficial in the treatment of cancer,” Ayer says.–Story Source–The above story is reprinted from materials provided by University of Utah Health Sciences, via EurekAlert!, a service of AAAS.
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    Cancer Cells Feed On Sugar-Free Diet
    ScienceDaily (Jan. 10, 2012) — Cancer cells have been long known to have a “sweet tooth,” using vast amounts of glucose for energy and for building blocks for cell replication.—Now, a study by a team of researchers at Johns Hopkins and elsewhere shows that lymph gland cancer cells called B cells can use glutamine in the absence of glucose for cell replication and survival, particularly under low-oxygen conditions, which are common in tumors.—Writing in the Jan. 4, 2012, edition of Cell Metabolism, Anne Le, M.D., and a team of investigators collaborating with the Johns Hopkins Brain Science Institute, say the finding is critical for developing innovative cancer therapies because it offers “proof of concept” evidence that curbing the growth of B cell cancers can be accomplished by inhibiting a glutamine enzyme called glutaminase.–Le notes that although little is known about glutamine’s role in the growth of B cell cancer, the amino acid circulates in the blood at the highest level among the 20 amino acids that do so.–The tricarboxylic acid cycle (TCA or Krebs cycle) is classically regarded as a pathway for glucose oxidation. However, the experiments by Le and the team show that B cells oxidize glutamine when glucose is absent.—The study also found that when oxygen is scarce, there is enhanced conversion of glutamine to glutathione, an important agent for controlling the accumulation of oxygen-containing chemically reactive molecules that cause damage to normal cells.—When the investigators used a glutaminase inhibitor, cancerous growth of B cells was stopped in petri dishes.—“The flexibility of the TCA cycle in using both glutamine and glucose pathways may be important for cancer cells to proliferate and survive, especially under the low-oxygen and nutrient-deprived conditions often encountered in the tumor microenvironment,” says Le.–Now, perhaps, scientists can exploit that survival strategy to stop cancer, according to former Johns Hopkins scientist Chi Dang, M.D., now at the Abramson Cancer Center at the University of Pennsylvania. “A broader and deeper understanding of cancer cell metabolism and cancer cells’ability to reprogram biochemical pathways under metabolic stress can be a rich ground for therapeutic approaches targeting tumor metabolism,” he says.—In addition to Le, an assistant professor in the Department of Pathology at the Johns Hopkins University School of Medicine, other researchers from Johns Hopkins who participated in this study include Sminu Bose, Arvin Gouw, Joseph Barbi, Takashi Tsukamoto, Camilo J. Rojas and Barbara Slusher. The Johns Hopkins Brain Science Institute, where Tsukamoto, Rojas and Slusher are faculty, is pursuing the development of new glutaminase inhibitor drugs.—Story Source-The above story is reprinted from materials provided by Johns Hopkins Medicine. –Journal Reference–Anne Le, Andrew N. Lane, Max Hamaker, Sminu Bose, Arvin Gouw, Joseph Barbi, Takashi Tsukamoto, Camilio J. Rojas, Barbara S. Slusher, Haixia Zhang, Lisa J. Zimmerman, Daniel C. Liebler, Robbert J.C. Slebos, Pawel K. Lorkiewicz, Richard M. Higashi, Teresa W.M. Fan, Chi V. Dang. Glucose-Independent Glutamine Metabolism via TCA Cycling for Proliferation and Survival in B Cells. Cell Metabolism, 2012; 15 (1): 110 DOI: 10.1016/j.cmet.2011.12.009
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    Statins linked with small diabetes risk
    Whether statins can make blood sugar rise enough that someone crosses the threshold to diabetes has been confusing. -A new side-effect seems to be emerging for those cholesterol-lowering wonder drugs called statins: They may increase some people’s chances of developing Type 2 diabetes.–A study adds to the evidence, finding a modest risk among older women who used a variety of statins. It’s a puzzling link, and specialists say people who most need statins because of a high risk for a heart attack should stick with the drugs.-“What I fear here is that people who need and will benefit from statins will be scared off of using the drugs because of reports like this,” says Dr. Steven Nissen, cardiology chairman at the Cleveland Clinic, who wasn’t involved with the research. “We don’t want these drugs in the water supply, but we want the right people treated[U2]. When they are, this effect is not a significant limitation.”–But more and more doctors are urging otherwise healthy people to use the pills as a way to prevent heart disease[U3]. For them, the findings add another potential complication as they consider whether to tackle their cholesterol with diet and exercise alone or add a medication.-“The statin should not be seen as the magic pill,”[U4] says Dr. Yunsheng Ma of the University of Massachusetts Medical School, who led Monday’s study of postmenopausal women.
    Heart risks of diabetes
    Statins are one of the most widely prescribed drugs, and among the most touted with good reason. They can dramatically lower so-called “bad” LDL cholesterol. Studies make clear that they save lives when used by people who already have heart disease.–What’s debated is how much the drugs help people who don’t yet have cardiovascular disease but whose chances are higher because of other factors such as smoking or high blood pressure — or diabetes.—In fact, long-term diabetes is so heart-risky that the American Diabetes Association urges fairly aggressive statin use by many diabetics. For everyone else, Nissen says the general rule is statins help people who have at least a 10 per cent chance of a heart attack in the next 10 years, something a doctor can calculate.
    All drugs have side-effects that are important to consider while deciding whether they’re a good bet for an individual. Statins have long been known to cause muscle pain that on rare occasions becomes a serious breakdown of muscle that can lead to kidney failure, even death.—Not to mention RNA damage—and lobotomizing the brain as well—But whether statins can make blood sugar rise enough that someone crosses the threshold to diabetes has been confusing.–After all, some of the same risks for heart disease — such as being overweight and sedentary — also increase the odds of developing Type 2 diabetes. And Ma says too many statin users wrongly assume the pills will let them eat whatever they want.
    Ma’s team examined a huge government study that tracked the health of postmenopausal women for many years. They culled the records of more than 153,000 women who didn’t have diabetes when they enrolled in the Women’s Health Initiative in the 1990s. Just 7 per cent were taking statins at the time. Fast forward to 2005: Nearly 10 per cent of the statin users had developed diabetes as a needed note of caution for women, saying there’s less certainty about the drugs’ overall effects in them. Stay tuned: Her own research aims to narrow down which statin users are more likely to experience a blood-sugar jump.
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    Rare ‘supersoldier’ ants created in Canadian lab
    Read 178 comments178
    McGill Unversity researchers were able to create supersoldier ants, which are a biological anomaly, in the lab. (Alex Wilder/alexanderwilder.com)
    As It Happens on super soldier ants8:09
    Canadian researchers have discovered how to make a certain kinds of ants develop into “supersoldiers”[U5] with huge oblong heads and giant vicious jaws.–The findings are significant because they show there is dormant genetic potential that can be invoked by changes in the environment and locked in place for a very long time, said lead author Ehab Abouheif, a McGill University biology professor, whose research was published Friday in the journal Science.–The authors suggest that hanging on to ancestral developmental toolkits can be an important way for organisms to evolve new physical traits.–“Birds with teeth, snakes with fingers and humans with ape-like hair – these are ancestral traits that pop regularly in nature,”[U6] Abouheif said. “But for the longest time in evolutionary theory, these ancestral traits were thought to go nowhere … the Barnum and Bailey of evolution. So they’ve been an unappreciated source of evolutionary variation.”—Typically, supersoldier ants are biological anomalies that occur rarely in nature and only in limited geographical regions. But the McGill researchers found these supersoldiers in unexpected regions and also created them by manipulating hormones.—Pheidole (big-headed) ant colonies contain millions of ants, including minor workers and soldiers. Depending on the food ants are fed, certain hormones are triggered in the ant larvae and they either develop into soldiers or minor workers.–Then there are supersoldier ants that block their nest entrance with their extra-large heads and fight with invading ants during army ant raids.–Abouheif and his team unexpectedly found supersoldier ants in the Pheidole species in Long Island where they aren’t normally seen. They were then able to artificially induce them in the lab by by dabbing the larvae with juvenile hormone, indicating that environmental cues can switch on the genetic machinery that produces supersoldiers.[U7]–“The kind of environmental stressors that evoke this dormant potential are there all the time, so when the need arises natural selection can take hold of the potential and actualize it,” said Abouheif.—“So what we’re showing is that environmental stress is important for evolution because it can facilitate the development of novel phenotypes. Any time you have a mismatch between the normal environment of the organism and its genetic potential you can release them – and these things can be locked in place for 30 to 65 million year
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    TOP E
    [U1]Glutamine Breaks down into 5 different amino acids and is the most abundant amino in the oesophagus-and intestine and stomach regions—it will converto to gaba-glutationie-glycine-glutamic acid and ghb—the glycine converts to glucagons( sugar ) which is required fro brain and liver and cellular energy
    [U2]“the right People/”” this is amazing these drugs are so damaging from the genetic code to the arterial integrity-RNA DNA damage—brain lobotomizing—who are these “ right people?
    [U3]This is unbelievable and the ignorance is what this report is showing the medical field is doing to healthy individuals to compromise there health
    [U4]First we are going to use a s preventative and now we are not to look at it as a magical pill
    [U5]Welcome to Canada EH!!! The land of Biodiversity and death—we export Nuclear energy ( bombs) food ( GMO WHEAT AND CANOLA ..ETC ) andd Now Pestilence–
    [U6]Genetic engineering experiments—anomalies created in a lab
    [U7]In other words they created these ants and put them on Long Island and were able to manipulate the Genetic code of these bugs—meaning we are now heading for a new Bio Warfare –we will just create a Super bug to inflict a people or Undesirables we do not want—we will give an ant a poison bite a butterfly with a knoxious sting –a flea to carry MRSA—etc.
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    Show of the Week January 20 2012
    Antioxidant, antiradical and antimutagenic activities of phenolic compounds present in maple products
    Effects of Maple (Acer) Plant Part Extracts on Proliferation, Apoptosis and Cell Cycle Arrest of Human Tumorigenic and Non-tumorigenic Colon Cells
    Recipe for Maple Syrup Extract
    Ingested Maple Syrup Evokes a Possible Liver-Protecting Effect—Physiologic and Genomic Investigations with Rats
    Fungus Contaminant in Corn, Peanuts, Soybeans- Chlorophyll Effective Against Aflatoxin
    An aqueous birch leaf extract of Betula pendula (tea or extract ) inhibits the growth and cell division of inflammatory lymphocytes
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    Antioxidant, antiradical and antimutagenic activities of phenolic compounds present in maple products
    (1) Research Research Laboratory in Sciences Applied to Food, Canadian Irradiation Center (CC), INRS-Institut Armand-Frappier, 531 Boulevard des Prairies, Laval, QC., H7V 1B7, CANADA–(2) Department of Food Science and Agricultural Chemistry, McGill University, 21, 111 Lakeshore, Ste-Anne de Bellevue, QC, H9X 3V9, CANADA
    AbstractThe phenolic compounds in maple sap and syrup were extracted at different periods of the season and were separated to collect the glycosylated compounds and the aglycone compounds. The antioxidant and antiradical activities of each phenolic compound were studied using the thiobarbituric acid reactive substances (TBARS) assay and the N,N-diethyl-p-phenylenediamine (DPD) decoloration test to measure the free radical scavenging. The results showed that in general the phenolic compounds had a good antioxidant and antiradical properties. The glycosylated compounds from maple sap and maple syrup showed a better activity than the aglycones.[U1] The antimutagenic effects of each phenolic compounds from maple sap and syrup were also investigated as the inhibition of SOS induction by chemical agents in Salmonella typhimurium TA1535/pSK1002 containing the fusion gene umuC-lacZ. Induction of the SOS gene (umuC) expression was assayed by measuring accumulated β-galactosidase activity using a modified Umu test. The antimutagenic properties were studied per se and after metabolisation by S9 fraction. The results showed that an optimum of antimutagenic properties of the glycosylated metabolites phenolic compounds from sap and syrup was observed at 75% of the season for the sap and at 25% of the season for the syrup. A higher antimutagenic activity was observed at 25% and 100% of the season for aglycones present in syrup and at 75% of the season for aglycones present in sap.
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    Effects of Maple (Acer) Plant Part Extracts on Proliferation, Apoptosis and Cell Cycle Arrest of Human Tumorigenic and Non-tumorigenic Colon Cells
    Phenolic-enriched extracts of maple sap and syrup, obtained from the sugar and red maple species (Acer saccharum Marsh, A. rubrum L., respectively), are reported to show anticancer effects. Despite traditional medicinal uses of various other parts of these plants by Native Americans, they have not been investigated for anticancer activity. Here leaves, stems/twigs, barks and sapwoods of both maple species were evaluated for antiproliferative effects against human colon tumorigenic (HCT-116, HT-29, Caco-2) and non-tumorigenic (CCD-18Co) cells. Extracts were standardized to total phenolic and ginnalin-A (isolated in our laboratory) levels. Overall, the extracts inhibited the growth of the colon cancer more than normal cells (over two-fold), their activities increased with their ginnalin-A levels, with red > sugar maple extracts. The red maple leaf extract, which contained the highest ginnalin-A content, was the most active extract (IC50 = 35 and 16 µg/mL for extract and ginnalin-A, respectively). The extracts were not cytotoxic nor did they induce apoptosis of the colon cancer cells. However, cell cycle analyses revealed that the antiproliferative effects of the extracts were mediated through cell cycle arrest in the S-phase. The results from the current study suggest that these maple plant part extracts may have potential anticolon cancer effects.
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    Ingested Maple Syrup Evokes a Possible Liver-Protecting Effect—Physiologic and Genomic Investigations with Rats
    Yuki WATANABE1), Asuka KAMEI1), Fumika SHINOZAKI1), Tomoko ISHIJIMA1)2), Kota IIDA2), Yuji NAKAI1)2), Soichi ARAI1)3) and Keiko ABE1)2
    1) Project on Health and Anti-aging, Kanagawa Academy of Science and Technology
    2) Graduate School of Agricultural and Life Science, The University of Tokyo
    3) General Research Institute, Tokyo University of Agriculture
    Rats fed a 20%-maple syrup diet (maple syrup group) for 11 d showed significantly lower values of the hepatic function markers than those fed a 20%-sugar mix syrup diet (control). The reason was suggested by a DNA microarray analysis which revealed that the expression of genes for the enzymes of ammonia formation were down-regulated in the liver of the maple syrup group.
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    Recipe for Maple Syrup Extract—
    if you cannot tap a tree then buy a maple syrup ( real maple syrup not a pancake syrup) pout it into a pot and at low heat simmer it –make sure you are there with the stuff or it will overflow—ask me how I know?—then with a wooden spoon stir it —when you get to about half way—stop the heat and pour it back in the container you got it from unless the container is plastic then use glass—take out another small portion 4 oz and pour it back into the pot—turn the heat on and continue letting it be warm for another 5 min or so.—then stop the stove and pour into a glass container—it will have almost gone frothy by then before you pour it in the container- allow to sit and it will crystallize –as a bonus you can ad essential oils or tinctures to this and when it crystallizes the fused oil will also be noticeable
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    Fungus Contaminant in Corn, Peanuts, Soybeans- Chlorophyll Effective Against Aflatoxin
    ScienceDaily (Dec. 29, 2009) — A new study has found that chlorophyll and its derivative chlorophyllin are effective in limiting the absorption of aflatoxin in humans. [U2]Aflatoxin is produced by a fungus that is a contaminant of grains including corn, peanuts and soybeans; it is known to cause liver cancer — and can work in concert with other health concerns, such as hepatitis.—-Levels of aflatoxin are carefully regulated in the United States, but are often found in the food supplies of developing nations, especially those with poor storage facilities.–OSU scientist George Bailey, a distinguished professor of environmental and molecular toxicology, pioneered studies of aflatoxin in China, where he found that in one region, one out of every 10 adults died from liver cancer.–But what has the science world particularly intrigued with this follow-up study is the methodology used by the researchers — a new “Phase 0” approach that safely tests low levels of carcinogens in human volunteers to measure the total aflatoxin exposure and to determine the effect of dietary chlorophlls on reducing this exposure.—Results of the study were just published in the journal Cancer Prevention Research.–Bailey and several other researchers, including lead author Carole Jubert, were part of the recent study. The journal also included a perspective written by a pair of Johns Hopkins researchers — Thomas Kensler and John Groopman — who praise the methodology and suggest that these Phase 0 “microdosing” studies should be expanded.–They wrote: “…microdosing studies with carcinogens have the potential to provide important insights into chemopreventive interventions and to enhance the overall clinical development and safety evaluation of preventive agents.”–The Phase 0 study “…may open the door for all kinds of new research,” said Jubert, a former researcher in Bailey’s lab at OSU’s Linus Pauling Institute. Jubert now works for Life Microsystems, an OSU spinoff company that hopes to continue work with natural products grown in Oregon, including pure chlorophylls.–“The technology is not particularly difficult,” she added. “It’s just a novel approach to evaluate toxin exposure in humans.”–In their study, Jubert and her colleagues gave very low doses of aflatoxin labeled with carbon-14 isotopes as a tracer to four human volunteers. They then gave the volunteers the same doses of aflatoxin along with doses of either chlorophyll or chlorophyllin, which previously had been shown to reduce carcinogen bioavailability in trout and rats. Using an accelerator mass spectrometer, they measured the rate of aflaxtoxin bioavailability. This technique is extremely sensitive, the researchers say, allowing measurement of minute amounts of any labeled compound.–Their research revealed rapid absorption of aflatoxin, which was significantly limited after the chlorophyll and chlorophyllin treatments.–“The beauty of this kind of ‘Phase 0’ study is the use of ultra-sensitive technology and ‘microdoses’ of environmental carcinogens to study toxicokinetics within the human body,” said John Mata, an OSU pharmacologist and second author on the study. “These measurements can be important because they allow us to better design future studies to understand the effects of dietary constituents on cancer risk.——–“In this case, clearly the results merit further study,” Mata added. “We showed that aflatoxin is absorbed quite rapidly and that chlorophyll and chlorophyllin have an ameliorating effect, preventing the toxin from getting into the bloodstream. Further studies can more precisely explore the interactions, as well as dosage levels.”—Jubert and Mata also have tested the feasibility of using similar technology on human exposure to other toxins, including smokers who ingest carcinogens through cigarette smoke.–Mata, a professor in OSU’s College of Veterinary Medicine, is a pharmacologist who previously worked in the drug industry. He said Phase 1 studies are designed to see if a compound is safe; Phase 2 expands the scope of the project, and Phase 3 looks at the compounds’ efficacy. Phase 0 represents a new concept — a way to measure the kinetics of a drug by using extremely small doses that pose little risk to the volunteers.–In this case, the amount of radiation given the human volunteers was equal to that you would encounter from a one-hour airplane ride; the level of aflatoxin administered was 1/30th the amount the Food and Drug Administration allows in a peanut butter sandwich.–Story Source-The above story is reprinted from materials provided by Oregon State University, via EurekAlert!, a service of AAAS.
    Simple Remedy—Use chlorophyll to reduce this or juice high amounts of peppermint –parsley-dandelion-watercress and drink glass amounts to offset this
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    An aqueous birch leaf extract of Betula pendula (tea or extract ) inhibits the growth and cell division of inflammatory lymphocytes.
    J Ethnopharmacol. 2011 Jul 14;136(3):444-51
    Authors: Gründemann C, Gruber CW, Hertrampf A, Zehl M, Kopp B, Huber R
    Abstract
    ETHNOPHARMACOLOGICAL RELEVANCE: Leaf extracts of Betula pendula have been traditionally used for the treatment of patients with rheumatoid arthritis (RA) or osteoarthritis. –AIM OF THE STUDY: We investigated the anti-proliferative capacity of an aqueous leaf extract of Betula pendula (BPE) on human primary lymphocytes in vitro, because activated lymphocytes play a major role in the initiation and maintenance of RA.–MATERIALS AND METHODS: Lymphocyte proliferation and cell division was measured by the activity of mitochondrial dehydrogenases and by using the membrane-permeable dye carboxyfluorescein diacetate succinimidyl ester (CFSE), respectively. Apoptosis was analyzed by surface staining of phosphatidylserine and intracellular activation of effector caspases 3 and 7 in comparison to the drug methotrexate using flow cytometric and photometrical analysis. In addition, the impact of the extract on cell cycle distribution was investigated by propidium iodide staining of DNA. For the bioassays BPE concentrations of 10-160 μg/mL were investigated. A phytochemical analysis, using LC-MS and HPLC, was conducted to identify the polyphenolic constituents of the birch leaf extract.
    RESULTS: Leaf extracts of Betula pendula inhibited the growth and cell division (CD8(+): 40 μg/mL: 45%; 80 μg/mL: 60%; 160 μg/mL: 87%) (CD4(+): 40 μg/mL: 33%; 80 μg/mL: 54%; 160 μg/mL: 79%) of activated, but not of resting T lymphocytes in a significant dose-dependent manner. The inhibition of lymphocyte proliferation due to apoptosis induction (compared to untreated control: 40 μg/mL: 163%; 80 μg/mL: 240%; 160 μg/mL: 348%) and cell cycle arrest was comparable to that of methotrexate. LC-MS analyses showed that the extract contains different quercetin-glycosides.–CONCLUSION: Our results give a rational basis for the use of Betula pendula leaf extract for the treatment of immune disorders, like rheumatoid arthritis, by diminishing proliferating inflammatory lymphocytes.–PMID: 21619918 [PubMed – indexed for MEDLINE]
    TOP F
    [U1]Definition of AGLYCONE: an organic compound (as a phenol or alcohol) combined with the sugar portion of a glycoside
    [U2]There is copper in this and this is anti mold-antifungal and antibacterial
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    Show of the Week January 23 2012
     
    First Link Between Potentially Toxic PFCs in Office Air and in Office Workers’ Blood
    Short, Sharp Shock Treatment for E. Coli
    Dietary DHA Linked to Male Fertility
    Pesticide Illnesses and GM Soybeans-Ban on Aerial Spraying Demanded in Argentina
    Kidney Stones—how to get rid of them
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    First Link Between Potentially Toxic PFCs in Office Air and in Office Workers’ Blood
    ScienceDaily (Jan. 18, 2012) — In a first-of-its-kind study, scientists are reporting that the indoor air in offices is an important source of worker exposure to potentially toxic substances released by carpeting, furniture, paint and other items. Their report, which documents a link between levels of these so-called polyfluorinated compounds (PFCs) in office air and in the blood of workers, appears in ACS’ journal Environmental Science & Technology.—-Michael McClean and colleagues explain that PFCs, used in water-repellent coatings on carpet and furniture, may have adverse effects on human health. The substances are widespread in the environment and in humans around the world. Scientists know that potential sources of exposure include food, water, indoor air, indoor dust and direct contact with PFC-containing objects. But the link between levels in air and blood had not been explored previously, so McClean’s group set out to fill that gap with a study of 31 office workers in Boston.—They found concentrations of a PFC called fluorotelomer alcohol (FTOH) in office air that were 3-5 times higher than those reported in previous studies of household air, “suggesting that offices may represent a unique and important exposure environment.” In addition, the study found a strong link between concentrations of FTOH in office air and perfluorooctanoic acid (a metabolite of FTOH) in the blood of office workers. The results also suggested that workers in newly renovated office buildings may receive considerably higher doses of PFCs than workers in older buildings.–The authors acknowledge funding from the National Institute of Environmental Health Sciences. –Story Source–The above story is reprinted from materials provided by American Chemical Society. —Note: Materials may be edited for content and length. For further information, please contact the source cited above.—-Journal Reference-Alicia J. Fraser, Thomas F. Webster, Deborah J. Watkins, Jessica W. Nelson, Heather M. Stapleton, Antonia M. Calafat, Kayoko Kato, Mahiba Shoeib, Verónica M. Vieira, Michael D. McClean. Polyfluorinated Compounds in Serum Linked to Indoor Air in Office Environments. Environmental Science & Technology, 2012; 46 (2): 1209 DOI: 10.1021/es2038257
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    Short, Sharp Shock Treatment for E. Coli
    ScienceDaily (Jan. 11, 2012) — A short burst of low voltage alternating current can effectively eradicate E. coli bacteria growing on the surface of even heavily contaminated beef, according to a study published in the International Journal of Food Safety, Nutrition and Public Health. The technique offers an inexpensive and easy to implement approach to reducing the risk of food poisoning, which can occur despite handlers complying with hygiene standards.—Food poisoning is a serious public-health issue, especially with the emergence of lethal and highly virulent strains of Escherichia coli (E. coli O157:H7, for example). Infection with this bacterium causes serious diarrhea, dehydration, kidney problems and can lead to serious long-term problems or even be fatal in children, the elderly and people with pre-existing health problems. Tens of thousands of people are affected by E. coli infection each year through eating contaminated beef and other food products. The US Centers for Disease Control and Prevention (CDC) estimates that about 2500 people are hospitalized and there are several dozen deaths each year.—Now, Ajit Mahapatra and colleagues at Fort Valley State University, in Georgia and Virginia Tech have demonstrated that applying a low-voltage alternating current to beef samples inoculated with large numbers of the potentially lethal E. coli O157:H7 can almost completely deactivate the bacterium, which is usually present on the surface of contaminated meat. The team points out that the level of contamination used in their tests far exceeded the contamination that would be seen in commercial carcasses after slaughter.—Previous researchers had demonstrated that electricity can kill bacteria effectively. The study by Mahapatra and colleagues proves efficacy against E. coli O157:H7 at low voltage and low alternating current. It offers a quick and easy way to decontaminate at-risk, but otherwise safe beef without recourse to microbicidal chemicals or other more complicated treatment processes.—Story Source-The above story is reprinted from materials provided by Inderscience Publishers, via EurekAlert!, a service of AAAS. –Note: Materials may be edited for content and length. For further information, please contact the source cited above.—Journal Reference-Donna L. Harris, Ajit K. Mahapatra, Baron L. Jones, Govind Kannan. Efficacy of low-voltage AC for inactivating surface adherent Escherichia coli O157:H7 on beef. International Journal of Food Safety, Nutrition and Public Health, 2011; 4 (2/3/4): 214 DOI: 10.1504/IJFSNPH.2011.044624
    SPECIAL NOTE—Remedy—So it would appear running A small cuurent of electricity to you foods may in fact assist in the prevention of pathogens that may infact creat a proble—so a good zapper or even a stunner set to low may in fact kill off any thing in the meats you are about to prepare
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    Dietary DHA Linked to Male Fertility
    ScienceDaily (Jan. 9, 2012) — Who knew that male fertility depends on sperm-cell architecture? A University of Illinois study reports that a certain omega-3 fatty acid is necessary to construct the arch that turns a round, immature sperm cell into a pointy-headed super swimmer with an extra long tail.—“Normal sperm cells contain an arc-like structure called the acrosome that is critical in fertilization because it houses, organizes, and concentrates a variety of enzymes that sperm use to penetrate an egg,” said Manabu Nakamura, a U of I associate professor of biochemical and molecular nutrition.—The study shows for the first time that docosahexaenoic acid (DHA) is essential in fusing the building blocks of the acrosome together. “Without DHA, this vital structure doesn’t form and sperm cells don’t work,” said Timothy Abbott, a doctoral student who co-authored the study.–Men concerned about their fertility may wonder what foods contain DHA. Marine fish, such as salmon or tuna, are excellent sources of this omega-3 fatty acid.[U1]–The scientists became intrigued with DHA’s role in creating healthy sperm when they experimented with “knockout” mice that lack a gene essential to its synthesis. “We looked at sperm count, shape, and motility, and tested the breeding success rate. The male mice that lacked DHA were basically infertile,” Nakamura said.—But when DHA was introduced into the mice’s diet, fertility was completely restored. “It was very striking. When we fed the mice DHA, all these abnormalities were prevented,” he said.—The scientists then used confocal laser scanning (3D) microscopy to look at thin slices of tissue in progressive stages of a sperm cell’s development. By labeling enzymes with fluorescence, they could track their location in a cell.–“We could see that the acrosome is constructed when small vesicles containing enzymes fuse together in an arc. But that fusion doesn’t happen without DHA,” he said.–In the absence of DHA, the vesicles are formed but they don’t come together to make the arch that is so important in sperm cell structure, he noted.–Nakamura finds the role this omega-3 fatty acid plays in membrane fusion particularly exciting. Because DHA is abundant in specific tissues, including the brain and the retina as well as the testes, the scientists believe their research findings could also impact research relating to brain function and vision.–“It’s logical to hypothesize that DHA is involved in vesicle fusion elsewhere in the body, and because the brain contains so much of it, we wonder if deficiencies could play a role, for example, in the development of dementia. Any communication between neurons in the brain involves vesicle fusion,” he noted.–The Illinois scientists will continue to study sperm; meanwhile, Nakamura has sent some of his DHA-deficient knockout mice to other laboratories where scientists are studying DHA function in the brain and the retina.–This work was supported in part by a CONACyT Mexico fellowship award.–Story Source-The above story is reprinted from materials provided by University of Illinois College of Agricultural, Consumer and Environmental Sciences. The original article was written by PhyllisPicklesimer. -Journal Reference-M. Roqueta-Rivera, T. L. Abbott, M. Sivaguru, R. A. Hess, M. T. Nakamura. Deficiency in the Omega-3 Fatty Acid Pathway Results in Failure of Acrosome Biogenesis in Mice. Biology of Reproduction, 2011; 85 (4): 721 DOI: 10.1095/biolreprod.110.089524
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    Pesticide Illnesses and GM Soybeans-Ban on Aerial Spraying Demanded in Argentina
    Coalition of doctors, health professionals and researchers demand ban on aerial spraying based on evidence documenting increase in pesticide-related illnesses since the introduction of GM soya. Dr Eva Sirinathsinghji——A network of 160 physicians, health workers and researchers in Argentina are demanding a ban on aerial spraying of pesticides based on increases in cancer and a range of pesticide-related illnesses since the introduction of genetically modified (GM) soybeans. These illnesses affect development, reproduction, the skin, as well as the immune, respiratory, neurological, and endocrine systems.–The network met in August 2010 [1] and again in 2011[2]. Following the 2010
    meeting an important report was compiled linking agrochemical exposure to significant increase in illnesses including birth defects and cancers in and around areas where agrochemicals are used. Increasing illness parallels the introduction and spread of GM soybeans tolerant to Monsanto’s glyphosate-based herbicide, Roundup. —-The striking link between illness and pesticide use presented at the first meeting led the Network Of Physicians Of Drop-Sprayed Towns to propose a complete ban on all aerial sprayings of pesticides, a complete ban of pesticides of toxicological types Ia (defined as extremely hazardous) and Ib (highly hazardous), and a ban on other pesticide use within 1 kilometre of residential areas. They also questioned the current agro-industrial and transgenic production model, stating that other options for agro-ecological production should be promoted and developed by the State University.–The second meeting called on local and national government to ensure people’s right to good health instead of the rights of agribusiness and private proprietors that currently prevail, and repeated their call for a complete ban on aerial spraying.—The Argentinean communities’ fight for judicial, healthcare and governmental
    recognition for health problems associated with pesticide use goes back 10 years. A summary compiled by non-governmental organisations and community residents is contained in the ‘Declaration of Caroya’. It documents [3] the “reduction in the average age and height” of residents in crop-sprayed towns “due to malnutrition”, and “decrease of the body’s natural defences.” In addition, “birth defects, mutagenesis, miscarriages, depression and suicide, disorders of the central nervous system and other neurological pathologies; disabilities, spina bifida, lupus, leukemia and other types of cancers; chloracne and other skin problems; asthma, allergies, and other respiratory and lung-related problems; male sterility and impotence; hormonal disruption and other hormonal disorders; diminished childhood development; prolonged febrile syndrome without focus; children’s increased vulnerability to pollutants; anemia, multiple sclerosis, cerebral ischemia, death..[U2]”—Alarming increases in birth defects, cancers, and other illnesses Public health officials have ignored ‘alarming notes coming from healthcare officials’ and consequently, very few epidemiological studies have been conducted. However the physicians (most of whom have been serving the same populations for over 25 years) have striking observational data that correlated with presentations and stories from people in the communities for a range of diseases associated with agrochemical exposure. They highlighted a systematic link between the unusual observations of recent years with this exposure. –The province of Chaco, where Dr Maria del Carmen Serveso heads a hospital intensive care unit, presented a devastating overview of rising illnesses in many towns. The illnesses include renal failure, birth defects in children of young mothers, cancers even in very young people, miscarriages, difficulty in becoming pregnant, respiratory problems and acute allergies; [U3]all linked by health teams to chemical contamination from agroindustrial farming recently imposed on the area replacing small-scale cotton farming and native forests. Respiratory illnesses were found to correlate with paraquat exposure.– One of the few epidemiological studies performed by Dr Gladys Trombotto, a geneticist from the University of Cordoba Maternity and Neonatal Unit, assessed 110 000 births over 10 years, and found a 2- and 3-fold increase in congenital and musculoskeletal defects respectively between 1971 and 2003 [4]. Child cancer data presented by Dr Otaño backed up what other physicians found in their own observations – incidence of birth defect rates increased significantly. He recorded 15.7 cases/100 000 in 2007 compared with the pre-existent level of 10.5 cases/100 000 in 1985—. The strong correlation of pesticide exposure with incidence of illness was exemplified by the observation made in 2005 by members of the Córdoba’s Ituzaingó neighbourhood, showing a higher rate of cancer in residents living closer to the fields that are sprayed. — The doctors suspect that the scale of damage to human health caused by agrochemicals is not fully recognized. The numbers of miscarriages may be higher than recorded levels, and other neurological and psychological problems are not currently being assessed. Preliminary and small-scale tests of children under a year of age suggest the existence of such illnesses in agrochemical use zones. [U4]
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    Kidney Stones—How to Get rid of them!

    #2622
    AvatarEK
    Keymaster

    R= Recipe
    If you have this condition then AVOID BEETS AND SPINACH AND ANY FOODS THAT WILL INCREASE OXALATE ACID AND OR URIC ACID—WHICH ARE THE BIGGEST CAUSE OF THISAsparagus-Parsley- Carrot—Spinach-Rhubarb-Chard-Beets-and Beet Leaves—Never mix with calcium or they will bind and cause the issue.are high in Oxalates
    RØMagnesium supplementation (400 – 600 mg per day) may inhibit Calcium Oxalate crystal formation in the Urine (Magnesium increases the solubility of Calcium Oxalate) and may thereby help to prevent Kidney Stones: –The Urine of Kidney Stones patients often has a reduced Magnesium:Calcium ratio.
    -Magnesium (combined with 100 mg Vitamin B6 per day) may cause partial elimination of Kidney Stones in 89% of Kidney Stones patients and total elimination in 79% of patients.-Magnesium supplementation may be very effective for preventing the reappearance of Kidney Stones in persons who have previously had Kidney Stones.
    Manganese may help to prevent Kidney Stones.
    Potassium may help to prevent Kidney Stones (by inhibiting the urinary excretion of Calcium).
    Selenium (combined with Vitamin E) may help to prevent Kidney Stones (by lowering elevated urinary excretion of Calcium and Oxalic Acid).
    Organic Acids
    RØCitric Acid may prevent recurrent Kidney Stones. –By consuming a good amount of citrus fruits will as well increase magnesium which will both balance out the kidneys and prevent or disperse kidney stones—-Another means would be to take citric acid powder and dissolve in water and add magnesium to it this will alleviate this —and as well some will take lemon juice and olive oil and mix 1 tablespoon of each in 2-3 oz of water and drink to assist with this and is also good for gall stones
    Inositol Hexaphosphate (Phytic Acid) may help to prevent and treat Kidney Stones.
    Phospholipids
    Phosphatidylcholine (PC) may prevent and dissolve Kidney Stones by emulsifying their constituent Lipids. Lecithin—Egg Yolk or Sunflower is preferred—utilizing this daily will as well increase phosphorus which will regulate the calcium and not allow it to build up
    Vitamins
    Vitamin B6 (10 – 100 mg per day) may prevent the formation of Kidney Stones caused by Hyperoxaluria (due to its role in the metabolism of Oxalic Acid).
    ØVitamin C may prevent the formation of Kidney Stones: -Kidney Stones do not normally develop as a result of consuming Vitamin C supplements. Human studies have shown that 10 grams per day of supplemental Vitamin C for long periods did not initiate or cause any Kidney Stones.
    Vitamin E (combined with Selenium) may help to prevent Kidney Stones (by lowering elevated urinary excretion of Calcium and Oxalic Acid).
    Water
    RØWater (when consumed in quantities sufficient to produce 2 – 3 quarts of Urine daily) may prevent the formation of Kidney Stones—if flushing with a distilled or RO water or Ionized water this will break up the calcium deposit and dilute the acid allowing the system to break and remove the excess
    These Foods/Herbs may Dissolve or Prevent Kidney Stones
    Algae
    Spirulina may help to prevent Kidney Stones and may help to prevent the damage to the Kidneys caused by Kidney Stones.
    Fruit- AS you can see either consuming a good dose of the citrus fruits or even juicing at home will eliminate or prevent stone formation
    Cranberry (juice) may help to prevent Kidney Stones.
    Grapefruit (juice) may help to prevent Kidney Stones (due to the Citric Acid content of Grapefruit). references
    Lemon (juice) may reduce the Pain of Kidney Stones and may facilitate their elimination.
    Orange (juice) may help to prevent Kidney Stones (due to the Citric Acid content of Oranges).
    Grains
    Barley Water may reduce the pain of Kidney Stones—making a barley milk or barley broth will increase the phosphorus which will regulate calcium in the kidney displacing the excess calcium—
    Herbs
    Blue Vervain may help to prevent and treat Kidney Stones. Buchu may help to treat Kidney Stones (according to folklore).
    RØBurdock may help to prevent and treat Kidney Stones.
    RØCollinsoni (Stoneroot) may accelerate the elimination of Kidney Stones. Cornsilk may break Kidney Stones up into fine grains which allows them to be eliminated (although it should be noted that Cornsilk has no effect on Oxalate Stones).
    Equisetum (Horsetail) is claimed to provide relief from the symptoms of Kidney Stones.
    Gravel Root is claimed to provide relief from the symptoms of Kidney Stones (according to anecdotal reports).
    Green Tea may help to prevent Calcium Oxalate Kidney Stones.
    Juniper Berries are claimed to provide relief from the symptoms of Kidney Stones (due to its Volatile Oil, Terpinen-4) (according to anecdotal reports).
    Parsley (juice diluted in Water) may facilitate the elimination of Kidney Stones. Phyllanthus (Phyllanthus niruri species) may help to prevent and treat Calcium Oxalate Kidney Stones.
    Seeds
    Pumpkin Seeds may reduce the incidence of Calcium Oxalate Stones.
    Vegetables
    RØParsnip may facilitate the elimination of existing Kidney Stones.-Juice this with parsely root or parsley and dandelion and will increase nutrient uptake and cleans the kidneys as well
    TOP G
    [U1]Other dietary Sources of DHA are Sea Algae and—
    (mg of DHA per 100 grams)
    Algae: Brown Algae Red Algae
    Eggs: Chicken Eggs 37 Omega Eggs 100
    Chicken Egg Yolk 114
    Fish Oils: Salmon Oil 18,200 Cod Liver Oil 11,000
    Sardine Oil 10,700 Menhaden Oil 8,560
    Herring Oil 4,210
    Meats: Brains – Lamb Ox 0.32
    Poultry: Chicken 40 Turkey 100
    Seafood: Cod 160 Haddock 126
    Halibut 250 Herring 1,080
    Eel * Salmon * 1,290
    Mackerel * 1,400 Trout *
    Sardines * Anchovy 911
    Caviar 3,800 Tuna 890
    Crab 361
    [U2]And this is just the tip of the iceberg here —this is what they know –this does not tell you what they do not know—this is a very elaborate way of wiping out and indigenious community without firing a bullet or wasting resources to eliminate a race or culture—and this is being done globally—MONSANTO = VATICAN—they Own Monsanto and started this company
    [U3]Seems Like Bio Warfare to me—
    [U4]I wonder who are the real terrorist here?religious zealots who you hear boo from or the silient but deadly chemical and agro megalith who bioterrorize indigenious people and take advantage of them who are not technologically at par—Makes you wonder eh!!
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    TOP H
    HOME
    Show of the Week January 27 2012
     
    BASF pulls out of European GM market
    Liver and thyroid cancer rates rise
    Shocking and Disturbed White Coats over exaggerates and sensationalizes false alarm on vitamin industry
    Micronutrient combination may boost male fertility
    Fertility and what to do to increase it—If you want to!!
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    BASF has announced it will pull the plug on its European operations in
    genetically modified plant development due to a lack of acceptance in the market.[U1]
    The German chemical and biotechnology company said it would relocate the headquarters of its BASF Plant Science group from Limburgerhof in Germany, to Raleigh in the USA.[U2] The company added that it will be concentrating its plant biotechnology activities on its main markets in North and South America in the future[U3]. The company added that its development and commercialisation of all GM products targeted solely at cultivation in the European market will be halted – these include four varieties of potato and one of wheat. We are convinced that plant biotechnology is a key technology for the 21st century. However, there is still a lack of acceptance for this technology in many parts of Europe – from the majority of consumers, farmers and politicians, said Dr. Stefan Marcinowski, a member of the BASF board of executive directors, responsible for plant biotechnology. It does not make business sense to continue investing in products exclusively for cultivation in this market ,he said. We will therefore concentrate on the attractive markets for plant biotechnology in North and South America and the growth markets in Asia. Acceptance for innovation? BASF cited a lack of consumer and industry acceptance as the main reason for its decision to halt European operations in GM products. [U4]It added that the decision to relocate to the USA was taken because there is less resistance to the technology. The announcement was celebrated by environmental campaign groups Greenpeace and Friends of the Earth: This is another nail in the coffin for genetically modified foods in Europe, said Adrian Bebb of Friends of the Earth. Whilst Greenpeace EU agriculture policy director Marco Contiero said the announcement shows that BASF admits Europeans don’t want GM crops. Europeans are not alone in rejecting GM food,” he added. “BASF’s retreat to the Americas follows a string of defeats for the industry over the last two years in China, India, the Philippines, Thailand and elsewhere. Over 90% of GM food crops are grown in just four countries in the Americas–However, the move by BASF has also been also been seen a major blow for science and innovation in the European market.[U5] Professor Denis Murphy of the University of Glamorgan, UK, warned that Europe is now in danger of becoming a scientific backwater and will be unable to assist developing countries the address food insecurity [U6]There is now a danger that we will lose, not only companies like BASF, but also academic researchers and students – as well as any influence that we have had previously in developing countries where we used to be major providers of assistance and expertise argued Murphy – an expert in biotechnology. BASF said it will adjust the portfolio and site footprint of its plant science to reflect the move. The chemical giant said the move to new headquarters for activities in the area of plant biotechnology at Raleigh in North Carolina will see the current HQ site in Limburgerhof, Germany retain 11 positions in some functions, such as regulatory experts for Europe. The division employees 157 people in Limburgerhof, plus another 63 at facilities elsewhere in Europe. BASF said it would relocate 123 of those jobs[U7] to the North Carolina facility. The company plans to close its sites in Gatersleben, Germany, and in Svalöv, Sweden. The announcement will mean a reduction of 140 jobs in BASF’s European operations. The company said it aims to offer the affected employees other positions within the BASF wherever possible. Our employees have done excellent work over the past years. We regret that we are losing these high-quality jobs in Germany and Sweden said Marcinowski
    [U1]ABOUT &^%$# TIME!!! Now we need to get them out of Canada and the USA as well and while we are at it out of the planet
    [U2]This really really really really is a disappointment—in plain English Blows—Why Would Raleigh allow BASF a foothold in the USA to further Poison America and Canada??
    [U3]Not Sure this is Acceptable—Maybe we should boycott this—Send this to everyone in North America –I don’t want them in Canada—and I am sure a lot like myself are not wanting them here either or in the USA for that Matter–
    [U4]I hate to say this the Euorpeans are a lot smarter then we are—they are getting rid of there poison we are going to allow it here —I am so excited—
    [U5]What a crock –what this is really saying is Loss Profits to rape developing countries and poison them with noxious foods
    [U6]Food Security??? With GE or GMO’s!? now they will at the least see the benefit of there health cost go down—this is why the EU is being hit economically
    [U7]123 slaves to develop poisons to kill off people—lets call it what it is—BS
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    Liver and thyroid cancer rates rise
    A “relatively large” increase in the prevalence of liver cancer, which is nearly 100 times less common than prostate cancer, has been reported by Statistics Canada.—The agency released its report, Canadian Trends in Cancer Prevalence, on Tuesday, calling it the first such detailed report of the trends in the country.–The five-year prevalence rate for cancer overall rose 2.1 per cent a year between 1997 and 2008, according to Statistics Canada. Wong Maye/Associated Press-Prevalence rates for prostate cancer, the most common cancer in Canada, rose substantially, mainly because of the aging of the population over the study period 1997 to 2008, according to the report.[U8] Increases in the prevalence of breast cancer, the second most common cancer and the most common in women, were “more moderate.” Prevalence is defined as all cancers diagnosed within a given period among people alive on a specified date. In contrast, “incidence” refers to newly occurring cases. The five-year prevalence rate for cancer overall rose 2.1 per cent a year between 1997 and 2008.
    Liver cancer factors
    Larry Ellison and Kathryn Wilkins of the agency’s health statistics division said both the incidence and observed survival rose over the study period, with only about 20 per cent of the increase in prevalence due to aging of the population.–Various explanations for rising liver incidence have been suggested, they said, including:
    Increases in immigrants from countries where hepatitis B and C virus infections and exposure to aflatoxins that can lead to liver cancer are more common.
    Rising incidence of hepatitis C infection linked to intravenous drug use and sharing of needles.
    Growing rates of obesity and Type 2 diabetes.[U9]
    Liver cancer was the least prevalent cancer studied, with a five-year prevalence proportion of 6.2 cases per 100,000 persons on Jan. 1, 2008. For perspective, the corresponding figure for prostate cancer was nearly 100-fold higher at 610 cases per 100,000 men, Statistics Canada noted.–Many countries have also reported increases in thyroid cancer [U10]incidence rates, especially among young and middle-age women. Advances in diagnostic techniques are thought to be a factor, though a recent U.S. study suggested more detection alone can’t explain the increase in that country, the authors said.–Radiological tests such as ultrasound and CT are picking up smaller lumps in the thyroid that aren’t visible in clinical exams and some of turn out to be malignant, said Dr. Ali Imran, director of the thyroid oncology and neuropituitary clinics at Dalhousie University in Halifax.–“Others have suggested a higher radiation exposure but that wouldn’t explain why it is commoner in women,” he added in an email.
    Rates declined for cancers of the larynx and a type of uterine cancer.The biggest disparity between the sexes was for lung cancer. The five-year prevalence proportion fell slightly among men but rose among women — a difference that was attributed to sharper decreases in smoking prevalence among men since the mid-1960s[U11]
    Suggestions—To Maximize Liver and Thyroid health Utilize Lugols Iodine as well as Tyrosine and Selenium—and the Use of Taurine + Milkthistle or Milk thistle and Vitamin C—Mame Teas with Sage and Rosemary as well—and consume sea weeds and watercress-parsley and dandelion as well—this will target anticancer os so many different levels
    And Eliminate all Grains ( GMO) and other foods Like SOY and CANOLA ) Nothing packaged-boxed or bag with few exceptions
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    Shocking and Disturbed White Coats over exaggerates and sensationalizes false
    alarm on vitamin industry
    The supplement trade must do more to combat the threat of spiking with unauthorized drugs or its critics
    will seize upon data unveiled on the Dr Oz show this week as further evidence that the industry is under-
    regulated,[U12] experts have warned. Dr Alex Schauss, chief executive of contract research organization
    AIBMR Life Sciences, was speaking following an investigation conducted by the Dr Oz show into spiking.
    Tests conducted by James Neal-Kababick, director of Oregon-based Flora Research Laboratories as part
    of the Dr Oz show investigation, revealed the presence of unauthorized active pharmaceutical ingredients
    (APIs), including some banned and potentially dangerous APIs, in supplements sold via multiple channels
    across the US. One supplement tested contained six times the levels of a drug banned by the FDA
    because of deaths associated with its use, while analysis of others revealed the presence of
    multiple banned APIs. Shocking and disturbing The findings were shocking and very disturbing and if
    continued will undermine consumer confidence unless effectively addressed,[U13] claimed
    Schauss, who has chaired the safety subcommittee of ComPLI (the Compliance and Label Integrity Committee
    of the Natural Products Association) since 1991. The levels of some of the APIs in these products was off the
    chart. But I think it also showed that this problem is not just limited to renegade supplement makers selling
    products on the internet, but to products sold all over the US in every kind of channel. [U14]Unfortunate
    lack of context However, it was unfortunate that a comment made by Neal-Kababick that nine out of 10 of his
    samples tested positive for APIs or their analogs was not clarified by Dr Oz, who left viewers with
    the erroneous impression that nine out of 10 supplements on the market were spiked with drugs,
    said Schauss. It was not made clear that the figures referred specifically to samples sent to Neal-Kababick’s lab
    because there were suspicions about them in the first place. It was also disappointing that comments
    made by another guest on the show – associate professor of medicine at Harvard University, Dr. Pieter Cohen –
    suggesting the solution was more regulation,[U15] were not challenged, said Schauss. He basically
    proposed a system where everything is tested before it is allowed to be put on the market. But
    that is not going to solve this problem. Anyone can send off a clean sample for testing – but is
    it the same product that you actually put on the market?[U16]” Laboratories with the expertise and
    experience to carry out forensic investigations Part of the problem was that rogue elements in the trade were
    getting ever more sophisticated at fooling those conducting analytical tests, said Schauss. There needs to be
    more help for people to know what methodologies they should be using to test for these substances and any
    analogs. He added: The information on what to test for and how is available and should be made available to
    stakeholders. It should be available to all QA/QC managers and directors. Manufacturers and distributors
    should be utilizing contract analytical laboratories that have the expertise and experience to carry out forensic
    investigations such as was performed for Dr Oz, if they don’t have the same quality of forensic capabilities.
    Meanwhile, retailers could also do more to demand from manufacturers and distributors selling them products
    to make sure this appropriate testing is done for any category of supplements where there is an economic
    incentive to mislead the public about a product’s content[U17], he said. Neal-Kababick, who recently alerted
    the trade to the I must say that I am seeing a rise in this problem not an abatement. Is that because more people
    are forwarding samples for us to test or is it because unethical midnight manufacturers are catching on to the
    opportunity? Regardless, we must remain vigilant, applying proper sampling plans and state of the art technology
    combined with strong phytoforensic techniques to assure that spiked raw materials do not make
    it into consume products[U18] Deliberate spiking or inadvertent contamination? Asked whether the APIs
    detected in samples passing through his labs were the result of deliberate spiking or inadvertent contamination
    due to poor supply chain controls, Neal-Kababick said: It’s both. We’re seeing more deliberate spiking with high
    levels of APIs but also more samples with low level Contamination. In the latter case, this might be due to
    manufacturers producing supplements in facilities that are also licensed to produce drugs, or where manufacturers
    are making counterfeit drugs and then producing ingredients or dietary supplements out of the same facility,
    he said. “Some of these companies use compressed air to clean up kit between batches – which can leave residues
    – instead of properly washing down the facility and then validating the cleaning as per pharmaceutical standard
    is sloppy manufacturing. He added: What is also worrying is that while most of the spiking is in weight loss, sports and
    male virility products, we’re also seeing more in anti-diabetic blood sugar support products – where we have
    detected anti-psychotic and blood pressure meds
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    Micronutrient combination may boost male fertility
    A combination of eight micronutrients may boost sperm quality and enhance the chance of conception, suggests new
    data from Austria.A study with 132 sub-fertile males showed that three months of supplementation with the nutraceutical
    combination resulted in improvements in measures of sperm quality by up to 215%.–The micronutrient
    combination was also associated with higher rates of conception, with 34 pregnancies reported
    during the six months that followed the study, compared with 11 in the control group, according to
    findings published in the European e-Journal of Clinical Nutrition and Metabolism—The Austria-based
    researchers used the branded PROfertil supplement, containing L-carnitine, L-arginine, zinc, vitamin
    E, glutathione, selenium, coenzyme Q10 and folic acid, all of which are said to be required for
    “optimal sperm cell metabolism, DNA synthesis during spermatogenesis, proliferation and anti-oxidative
    protection. –In consideration of their biochemical function, these ingredients are of great significance for male
    reproduction wrote researchers led by Martin Imhof from the Fertility Clinic IMI in Vienna. Nutrients and
    fertility Sub-fertility in men is reported to account for between 25 and 30% of all infertility causes, and is
    listed as one of the many reasons that birth rates are falling in Western countries. [U19]In addition, about
    50% of male fertility is the result of unknown causes (idiopathic), said the Austria-based researchers, and
    nutrition has been touted as a potential way of boosting the quality of sperm. —[U20]The new study
    assessed the potential of a non-prescription nutraceutical containing eight micronutrients on sperm quality
    in 132 sub-fertile males with a mean age of 34, while 73 sub-fertile men with a mean age of 38 participated
    as controls.–The nutraceutical group received supplements providing total daily doses of 440 mg
    L-carnitine, 250 mg L-arginine, 40 mg zinc, 120 mg vitamin E, 80 mg glutathione, 60
    micrograms of selenium, 15 mg coenzyme Q10, and 800 micrograms of folic acid. The
    supplement was provided by Vienna-based Lenus Pharma GmbH. Results showed that men receiving
    the active supplement displayed a 33% improvement in ejaculatory volume, a 215% improvement
    in sperm cell density, and a 23% improvement in total sperm motility.[U21]These increments
    were significantly higher than those observed among controls, added Imhof and his co-workers. Limitations
    and potential We recognize the non randomized placebo controlled design of our study as a limitation said the
    researchers. However, a double blind, randomized, placebo-controlled study is currently on the way to support
    these preliminary results. Despite mentioned limitations and in light of the fact that therapies for sub-fertile men
    are still missing, the investigated compound is a promising therapeutic approach, improving sperm parameters
    and enabling natural conception for couples with idiopathic male infertility they concluded. Source: the European
    e-Journal of Clinical Nutrition and Metabolism Published online 3 December 2011, doi:10.1016/j.eclnm.2011.11.002
    Improvement of sperm quality after micronutrient SupplementationAuthors: M. Imhof, J. Lackner, M. Lipovac, P.
    Chedraui, C. Riedl
    **************************************************************************************************
    Fertility and what to do to increase it—If you want to!!
    Wheatgerm oil—has been utilized since the 1920’s to increase pregnancies in bot women and animals to increase births—it increase both the fertility of men and women –Apply 1-2 tablespoon daily
    Vitamin E from non soy sources—olive –rice-palm-wheat-almond oil—increases fertility in both men and women—400-800mgs a day or 1 tablespoon of the oils mentioned
    Acetly L Carnitine —2 grams a day increases Sperm Count
    Arginine -2-3 grams a day also increase sperm count as well for both genders increases Nitric oxide to the genital area
    Selenium- a must for the males—every load ejaculated releases the selenium to protect the seed as it travels—It protects the sac from cancer 200mcg 2 times a day
    Zinc –to sustain insulin and protect prostate 30 mgs 2 times a day
    Male Combo for the reproductive is Zinc 30 mgs Selenium 200 mcg and Vitamin E-400IU
    Fats are required for both genders to increase hormonal health and a healthy reproductive system
    Another Combination For Men and Women is
    B5-adrenal support-Choline –Connection support-and Arginine Heart Support—when combined they have a synergy to turn the switch on and can help sustain the the activities as well
    Consuming foods such as walnuts- peanuts-almonds-sunflower seeds-pumpkin seed will increase the Male reproductive system—
    Things to Avoid—Soy—Peas—Xenoestrogens-Canola-GMO Corn—Chemicals in general
     
    TOP H
    [U1]ABOUT &^%$# TIME!!! Now we need to get them out of Canada and the USA as well and while we are at it out of the planet
    [U2]This really really really really is a disappointment—in plain English Blows—Why Would Raleigh allow BASF a foothold in the USA to further Poison America and Canada??
    [U3]Not Sure this is Acceptable—Maybe we should boycott this—Send this to everyone in North America –I don’t want them in Canada—and I am sure a lot like myself are not wanting them here either or in the USA for that Matter–
    [U4]I hate to say this the Euorpeans are a lot smarter then we are—they are getting rid of there poison we are going to allow it here —I am so excited—
    [U5]What a crock –what this is really saying is Loss Profits to rape developing countries and poison them with noxious foods
    [U6]Food Security??? With GE or GMO’s!? now they will at the least see the benefit of there health cost go down—this is why the EU is being hit economically
    [U7]123 slaves to develop poisons to kill off people—lets call it what it is—BS
    [U8]Makes sense the Soy in the diet over a period of time has increased this type of cancer as well as Canola oil and other processes and not to mention the fact Canada is a leading developer of GMO foods which would contribute to this dilemma we all Face in Canada as well as other parts of the Planet
    [U9]None Of these Statistics would give these kind of number –None of them –this is a misdirecting of facts—on something of this scale it would have to be more to a common thread—foods Poisoning –and environmental exposure to solvent or chemicals or emf which would cause this
    [U10]Again this could be tied to Soy and Pesticide exposure—Not to mention Vaccinations which would in fact destroy both liver and thyroid
    [U11]Smoke and Mirrors–
    [U12]Under Regulated –or Over cautious—theDSHEA allows and provides all the regs that are needed—what is transpiring here is a retalitary effect from the FDA to use White Coats to force Peer pressure to change the 2 officials from gov’t
    [U13]ALLLLL HS!! This is about the FDA getting there fingers rapped—They had over stepped there power—and were told that they did not need more power –they had enough todo what was needed—this is about White Coats denying access to supplements
    [U14]OH OH we are now going to scare you into a lulled sense of security making you think that supplements are dangerious—OOOooOO the boogey man is going to get you Now!!! No ONE has ever Died from a vitamin –No One—Butttt People die from drugs and the number one killer is aspirin—and why are you not hearing this from so called campaigner for health??
    [U15]Regulation = Denied Access—and what they –the white coats working for the FDA want to do is Undermine your right to health by making you more dependent on Pharmaceuticals that shut down your brain—your spirit and your soul
    [U16]The FDA shut down it’s Labs years ago just like HPB in Canada did allowing the industry to test—this used to be a secondary line of defence—the problem was it was to easily corrupted by the very corporations handing in those samples so they bought out the branches of Gov’t and now conduct there own in house test—any one can fabricate anything—and todays vitamins by mainstream drug companies are the worse ones with the most additives and poisons
    [U17]Again this is such Rubbish and BS—the Health fod industry is more regulated then the Pharmaceutical industry HUGELY—and as has been reported No one has ever died from taking supplements—but many have died from pharmaceuticals and in fact a lot of them are poisonous and have all these analysis’s done and still people are getting rooked—-so the answer really is stop buy foreign raw materials and start getting raw materials locally—will never happen due to cost and money lost with hyper inflating things made at home
    [U18]Aren’t Pharmaseuticals Consumer Products??? And yet where is the outcry here!!—this is an elaborate art of persuasion to get people afraid of there supplements
    [U19]Birth rates are falling due to lack of semen from fluoride-soy-pesticides and xenoestrogens in everyday exposure and including biowarfare being done on the human race—with different waves of infection
    [U20]Shutting down the endocrine system and not feeding people what is required to sustain a health reproductive system would be more the case
    [U21]Arginine and acetyl L Carnitine is what they give guys who are porn stars to increase flow—it does work when trying to get pregnant add selenium with this —males lose there selenium when having intercourse due to the ejaculation so it is good to supplemet to protect the sac
    *******************************************************************************************************************
    TOP I
    HOME
     
    Show of the Week Jan 30 2012
     
    The Bitter Truth About Splenda
    High Levels of MRSA Bacteria in U.S. Retail Meat Products, Study Suggests
    Environmental Exposure to Organochlorines May Impact Male Reproduction
    Pesticide Metabolites Associated With Increased Risk Of Testicular Cancers
    Nettle has protective activity of beta-cells of langerhans in hyperglycemic rats
    ******************************************************************
    The Bitter Truth About Splenda
    ‘If you were told to ingest a biologically alien synthetic chemical whose presence on this planet did not predate 1976, and whose structure is only a few atoms away from the deadly pesticide DDT, and you knew that not only were there no long term human safety studies performed on it, but that it had been already proven in tests to have following adverse health effects would you still consume it?’
    · Shrunken thymus glands (up to 40% shrinkage)
    · Enlarged liver and kidneys.
    · Abnormal histopathological changes in spleen and thymus
    · Increased cecal weight
    · Reduced growth rate
    · DNA Damage
    · Adverse changes to gastrointestinal bacteria
    · Abnormal Pelvic Mineralization
    · Decreased red blood cell count
    · Hyperplasia of the pelvis
    · Aborted pregnancy (Maternal & Fetal Toxicity)
    · Decreased fetal body weights and placental weights
    · Bowel inflammation
    · Triggering migraine
    · Increase glycosylation of hemoglobin (HbA1c) for diabetics
    ….would you still consume it? Of course not! And yet, millions of Americans (including our precious children!) are doing exactly that by consuming Splenda. So, what is sucralose, chemically speaking?
    Like “Splenda,” the term “sucralose” is a cute little marketing ploy. The true name of this ugly little chemical is actually too long for the human tongue to comfortably pronounce (which is usually an excellent indication that it is not safe to ingest!) Go ahead and see if you can wrap your vocal chords around this phonetic monstrosity:
    1,6-dichloro-1,6-dideoxy-BETA-D-fructofuranosyl-4-chloro-4-deoxy-alpha-D-galactopyranoside
    Despite the intended insinuation, sucralose is not a form of sucrose (cane sugar). Sucralose/Splenda is produced through artificially substituting three hydroxyl groups (hydrogen + oxygen) with three chlorine atoms in the sugar (sucrose) molecule. Natural sugar is a hydrocarbon built around 12 carbon atoms.
    When transformed into Splenda it becomes a chlorocarbon, in the same family as deadly pesticides like DDT, insecticides, biocides, disinfectants like Chlorox Bleach, and WWI poison gas like dichlorourea.
    The makers of sucralose/Splenda argue that this “remarkably stable” chemical passes unchanged into the urine and feces, when in fact, up to 11% to 27% is absorbed into the body (FDA, 1999). In fact, the varying degrees to which sucralose is absorbed is used as a marker for gut and intestinal permeability to determine certain disease states. Once absorbed, some portion of this chlorocarbon accumulates in the body (between 1.6% to 12.2%). What effects will these accumulated chemicals have?
    According to James Bowen, M.D:
    “Any chlorocarbons not directly excreted from the body intact can cause immense damage to the processes of human metabolism and, eventually, our internal organs. The liver is a detoxification organ which deals with ingested poisons. Chlorocarbons damage the hepatocytes, the liver’s metabolic cells, and destroy them. In test animals Splenda produced swollen livers, as do all chlorocarbon poisons, and also calcified the kidneys of test animals in toxicity studies.”
    How can this be true for an FDA approved sweetener?
    FDA approval does not in any way guarantee safety…..sadly enough, in many cases, it guarantees the exact opposite. Take aspartame for instance. Aspartame (Equal/NutraSweet) contains 10% methanol, which is broken down in our body into two extremely toxic substances: formaldehyde and formic acid. There are over 30 known adverse health effects associated with its consumption! This sweetener gained FDA approval in 1981, despite appalling evidence linking it to cancer, particularly, brain cancer.
    So, if Splenda is not a viable alternative to sugar, what can we use instead?
    When one uncouples the experience of “sweetness” from caloric content, the body becomes confused because it does not receive nourishment and therefore will not attain satiety – this, in turn, leads to overindulgence. Indeed, new studies have shown exactly this: those who consume synthetic sweeteners are more prone to obesity. What this means is that when we ingest something sweet, it should also have caloric and nutritional content. Anything less than this equation is a recipe for failure and ill health.
    Thankfully Nature provides us with a veritable cornucopia of healthy sweeteners: honey, stevia, xylitol, erythritol , maple syrup or sugar, coconut nectar or sweetner , malitol, and birch tree syrup all of which are available at a local health food store or ethnic market. Next time that sweet tooth calls, remember not to succumb to advertising hype which would convert poisonous chemicals into “magical” no-calorie sweeteners. Use both common sense and a sense of moderation, and your body will thank you.
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    High Levels of MRSA Bacteria in U.S. Retail Meat Products, Study Suggests
    ScienceDaily (Jan. 20, 2012) — Retail pork products in the U.S. have a [U1]higher prevalence of methicillin-resistant Staphylococcus aureus bacteria (MRSA) than previously identified, according to new research by the University of Iowa College of Public Health and the Institute for Agriculture and Trade Policy.–MRSA can occur in the environment and in raw meat products, and is estimated to cause around 185,000 cases of food poisoning each year. The bacteria can also cause serious, life-threatening infections of the bloodstream, skin, lungs and other organs. MRSA is resistant to a number of antibiotics.—The study, published Jan. 19 in the online science journal PLoS ONE, represents the largest sampling of raw meat products for MRSA contamination to date in the U.S. The researchers collected 395 raw pork samples from 36 stores in Iowa, Minnesota and New Jersey. Of these samples, 26 — or about 7 percent — carried MRSA.—“This study shows that the meat we buy in our grocery stores has a higher prevalence of staph than we originally thought,” says lead study author Tara Smith, Ph.D., interim director of the UI Center for Emerging and Infectious Diseases and assistant professor of epidemiology. “With this knowledge, we can start to recommend safer ways to handle raw meat products to make it safer for the consumer.”
    The study also found no significant difference in MRSA contamination between conventional pork products and those raised without antibiotics or antibiotic growth promotants.
    “We were surprised to see no significant difference in antibiotic-free and conventionally produced pork,[U2]” Smith says. “Though it’s possible that this finding has more to do with the handling of the raw meat at the plant than the way the animals were raised, it’s certainly worth exploring further.”–Story Source-The above story is reprinted from materials provided by University of Iowa, via Newswise. –Journal Reference-Ashley M. O’Brien, Blake M. Hanson, Sarah A. Farina, James Y. Wu, Jacob E. Simmering, Shylo E. Wardyn, Brett M. Forshey, Marie E. Kulick, David B. Wallinga, Tara C. Smith. MRSA in Conventional and Alternative Retail Pork Products. PLoS ONE, 2012; 7 (1): e30092 DOI: 10.1371/journal.pone.0030092
     
    Food Statistics > Pork consumption per capita (most recent) by country
    Showing latest available data.
    Rank
    Countries
    Amount
    # 1
    Denmark:
    142.6
     
    # 2
    Spain:
    123
     
    # 3
    Hong Kong:
    121.9
     
    # 4
    Germany:
    117
     
    # 5
    Hungary:
    90.2
     
    # 6
    Poland:
    83.2
     
    # 7
    Sweden:
    79.4
     
    # 8
    France:
    76.6
     
    # 9
    China:
    75
     
    # 10
    Singapore:
    69.1
     
    # 11
    Canada:
    66.2
     
    # 12
    United States:
    62.8
     
    # 13
    United Kingdom:
    54.3
     
    # 14
    Australia:
    40
     
    # 15
    Japan:
    36.1
     
    # 16
    Russia:
    29
     
    # 17
    Mexico:
    22.4
     
    # 18
    Brazil:
    20.2
     
     
    Total:
    1,309
     
     
    Weighted average:
    72.7
     
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    Environmental Exposure to Organochlorines May Impact Male Reproduction
    ScienceDaily (Jan. 9, 2012) — Melissa Perry, Sc.D., M.H.S., professor and chair of the Department of Environmental and Occupational Health at the GW School of Public Health and Health Services and adjunct associate professor at the Harvard School of Public Health, led an observational study indicating that environmental exposure to organochlorine chemicals, including Polychlorinated Biphenyls (PCBs) and p,p’-DDE (the main metabolite of the insecticide DDT) can affect male reproduction.–The research was published online on Dec. 21, 2011 in the journal Environmental Health Perspectives. —The researchers studied 192 men who were part of couples that were sub-fertile, to see if the men with higher levels of organochlorines in their blood showed evidence of increased rates of sperm abnormalities. They looked for sperm disomy, which occurs when sperm cells have an abnormal number of chromosomes. While all men have a certain number of sperm with such abnormalities, researchers found that men with higher levels of DDE and PCBs had significantly higher rates of sperm abnormalities.–“This research adds to the already existing body of evidence suggesting that environmental exposure to certain chemicals can affect male fertility and reproduction. We need to further understand the mechanisms through which these chemicals impact sperm,” said Dr. Perry. “While we cannot avoid chemicals that already persist in the environment, it is imperative that decisions about putting biologically active chemicals into the environment need to be made very carefully, because there can be unanticipated consequences down the road.”-The researchers used a new sperm imaging methodology developed by Dr. Perry and colleagues to detect the chromosomal abnormalities, which allowed them to study a larger sampling of individuals than previous studies.–Story Source-The above story is reprinted from materials provided by George Washington University Medical Center.
    ***********************************************************************
    Pesticide Metabolites Associated With Increased Risk Of Testicular Cancers
    ScienceDaily (Apr. 29, 2008) — Men exposed to organochlorine pesticide metabolites, such as DDE, had an increased risk of testicular germ cell tumors. Previous research suggested that persistent exposure to organochlorine pesticides may increase the risk for some types of testicular cancer, but that observation had not been replicated in an independent data set.—In the current case-control study, Katherine McGlynn, Ph.D., of the National Cancer Institute in Bethesda, Md., and colleagues measured the amount of pesticides or their metabolic breakdown products in blood samples from men who were later diagnosed with testicular germ cell tumors and in blood samples from healthy controls. The men were all part of the U.S. Servicemen’s Testicular Tumor Environmental and Endocrine Determinants study. The 915 control subjects and 739 case subjects had donated blood samples an average of 14.2 years prior to the current analysis.–When the researchers divided the participants into quartiles based on the concentration of a particular pesticide in their blood, the team saw a trend for an increased risk of testicular cancer in men with higher concentrations. The trend reached statistical significance for some of the pesticides and metabolites tested. For example, men in the highest quartile for DDE (p,p’-dichlorodiphenyldichloroethylene)–which is a persistent metabolite of DDT (p,p’-dichlorodiphenyltrichloroethane)–were 1.7 times more likely to develop testicular germ cell tumors than those with the lowest concentration.—“If the relative risks calculated in this study are accurate, the population-attributable risk of DDE (i.e., the propor¬tion of disease in the study population that is attributable to DDE exposure) would be approximately 15 percent for all [testicular germ cell tumors],” the authors write.–This research was reported April 29 in the Journal of the National Cancer –Story Source-The above story is reprinted from materials provided by Journal of the National Cancer Institute, via EurekAlert!, a service of AAAS.
    ****************************************************************************
    Nettle has protective activity of beta-cells of langerhans in hyperglycemic rats.The protective activity of Urtica dioica leaves on blood glucose concentration and beta-cells in streptozotocin-diabetic rats.
    Pak J Biol Sci. 2007 Apr 15;10(8):1200-4
    Authors: Golalipour MJ, Khori V
    This study was done to determine the protective activity of the hydroalcholic extract of Urtica dioica leaves on Hyperglycemia and beta-cells in hyperglycemic rats. Thirty Wistar rats were allocated in groups of normal, Diabetic and treatment. Hyperglycemia in Rats induced by 80 mg kg(-1) streptozotocin. In treatment group, animals received hydroalcholic extract of Urtica dioica 100 mg kg(-1) day(-1) for five days, intraperitoneally and then hyperglycemia induced by streptozotocin. The blood glucose concentration was measured by using a Glucometer in 1st, 3rd and 5th weeks. In the end of 5th weeks the animals in each group were sacrificed by anesthesia and whole pancreas in three groups extracted and fixed in bouin’s fluid and stained by chromealum hematoxiline-phloxine and beta cells were counted in three groups by Olympus microscope. Mean +/- SE of blood glucose concentrations in the end of fifth weeks were 99.4 +/-5.0, 454.7 +/- 34.5 and 303.6 +/- 100.6 in control, diabetic and treatment groups, respectively (p < 0.05). The percentages of beta-cells in control, diabetic and treatment groups were 73.6, 1.9 and 22.9%, respectively. The percentage of beta-cells in treatment group comparing with diabetic group was significant (p < 0.05). This study showed that the protective administration of hydroalcholic extract of Urtica dioica has hypoglycemic effect and protective activity of beta-cells of langerhans in hyperglycemic rats.—PMID: 19069917 [PubMed – indexed for MEDLINE]
    Recipe –add Nettle to a blender and distilled water to it and alcohol—measure this so that the water will be 50/50 with the alcohol—and add to blender and then add the nettle 1/3 rd the amount to the water/alcohol mix—blend this at high speed for about 10 minutes and strain —you will have made an extract—use a half a tsp as needed
    Another means to do this is to add nettle with cinnamon bark and juniper berry—place all 3 components in a coffee percolator and then seal the containment area—and add distilled water to the pot—fill it to the mark and then allow it to perk on the stove for about 10 minutes or allow it to get about 1-2 inches from the bottom—pour out to a bottle and when it cools add alcohol to it 2:1 to the extract—use ½ tsp several times a day
    These recipes have other uses as well not just for diabetic conditions but for a host of others as well ranging from anti bacterial-antifungal-antiviral-male issues-anti cancer issues-anti microbial issues-blood-organ –immune –antioxidant-and many more –something that can be gotten from the woods or from any open field –if gotten from out doors make sure you clean these with some kind of cleaning method to remove potential chemtrail and GMO fall out
    TOP I
    [U1]This whole report should have everyone alarmed and cautious about where and what meat they buy—this would include kosher and Hal el as well –if the meat can get contaminated with MRSA which is something coming out of the medical field or clinical or pharmaceutical setting thennnnn we have a problem with somebody doing this purposely—they are trying to get us all to be livestock grazing on veges—the largest consumers of this tpe of foods are –Asians—are we in Biowarfare?
    Something to think about
    [U2]In other words the so called natural meats in a health food store may not have any significance

    #2623
    AvatarEK
    Keymaster

    Scientists urge unis to axe alternative medicine courses
    http://www.smh.com.au/national/tertiary-education/scientists-urge-unis-to-axe-alternative-medicine-courses-20120125-1qhtm.html#ixzz1kfhkv29t
    University reputations at stake … a new lobby group for doctors and scientists claims undeserved credibility is given to disciplines “better described as quackery”. [U1]MORE than 400 doctors, medical researchers and scientists have formed a powerful lobby group to pressure universities to close down alternative medicine degrees.–Almost one in three Australian universities now offer courses in some form of alternative therapy or complementary medicine, including traditional Chinese herbal medicine, chiropractics, homeopathy, naturopathy, reflexology and aromatherapy.–But the new group, Friends of Science in Medicine, [U2]wrote to vice-chancellors this week, warning that by giving “undeserved credibility to what in many cases would be better described as quackery” and by “failing to champion evidence-based science and medicine”[U3], the universities are trashing their reputation as bastions of scientific rigour.–The group, which names world-renowned biologist Sir Gustav Nossal and the creator of the cervical cancer vaccine Professor Ian Frazer among its members, is also campaigning for private health insurance providers to stop providing rebates for alternative medical treatments.[U4]—A co-founder of the group, Emeritus Professor John Dwyer, of the University of NSW, who is also a government adviser on consumer health fraud, said it was distressing that 19 universities were now offering “degrees in pseudo science”.[U5]—“It’s deplorable, but we didn’t realise how much concern there was out there for universities’ reputations until we tapped into it,” Professor Dwyer said. “We’re saying enough is enough. Taxpayers’ money should not be wasted on funding [these courses] … nor should government health insurance rebates be wasted on this nonsense.”–Professor Dwyer said it was particularly galling that such courses were growing in popularity while, at the same time, the federal government was looking at ways to get the Therapeutic Goods Administration to enforce tougher proof-of-efficacy criteria for complementary medicines, following the release of a highly critical review by the Australian National Audit Office last September.–Of particular concern to the group is the increase in chiropractic courses, following the recent announcement of a new chiropractic science degree by Central Queensland University. More than 30 scientists, doctors and community advocates wrote to the vice-chancellor and health science deans at the university voicing their concern, which laid the foundations for Friends of Science in Medicine. –The groundswell of protest from medical professionals comes after a decision in Britain that means from this year it will no longer be possible to receive a degree from a publicly-funded university in areas of alternative medicine, including homeopathy and naturopathy.–German and British medical insurance providers are also in the process of removing alternative therapies from the list of treatments they will cover.–[U6]Australia’s vice-chancellors will meet in March and Professor Dwyer said his group was aiming to get a commitment from them to endorse health courses only with evidence-based science.[U7]—The spokesman for Universities Australia said tertiary institutions were self-accrediting. “[They have] the autonomy … to ensure the quality and relevance of the courses they offer,” he said.–The Tertiary Education Quality and Standards Agency, a government body set up to regulate higher education, refused to comment.–Most health funds pay rebates for alternative therapies under top cover polices. Private Healthcare Australia did not return the Herald’s calls.–
    Read more: http://www.smh.com.au/national/tertiary-education/scientists-urge-unis-to-axe-alternative-medicine-courses-20120125-1qhtm.html#ixzz1kfi9muA0
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    Morgellons– Unexplained Skin Condition Is Non-Infectious, Not Linked to Environmental Cause
    ScienceDaily (Jan. 25, 2012) — The US Centers for Disease Control and Prevention has completed a comprehensive study of an unexplained skin condition commonly referred to as Morgellons and found no infectious agent and no evidence to suggest an environmental link.[U8]—The full results are reported in the Jan. 25 issue of the online journal PLoS ONE.—In this study, investigators took an in-depth look at a skin condition characterized by unexplained lesions that contain fibers, threads, or other foreign material, accompanied by sensations of crawling, biting, or stinging. The condition is not currently recognized as a distinct clinical disorder with established diagnostic criteria. However, increasing inquiries to the CDC in 2006-2009 regarding the condition prompted the study in Northern California, where many of the persons who reported these symptoms lived.—The researchers found and enrolled 109 persons with symptoms of this condition by searching through the electronic medical record database of a large HMO. They conducted extensive testing to rule out infectious causes, and found no indication that the condition was attributed an infection.[U9] The researchers also determined that the fibers associated with the lesions were apparently fragments of cloth or other debris.[U10] The investigators showed that the condition is uncommon, estimating that it results in fewer than four out of 100,000 people seeking medical attention. About half of the study participants had evidence of other medical, most commonly psychiatric, illnesses.–The CDC suggests that people suffering with symptoms similar to those reported in the study should see their health care provider for a complete physical to ensure proper diagnosis of all illnesses, including psychiatric, and follow the recommended treatments.—“We found no evidence that this condition is contagious, or that suggests the need for additional testing for an infectious disease[U11] as a potential cause,” says Dr. Mark Eberhard, Director of CDC’s Division of Parasitic Diseases and Malaria and a lead study investigator. “This alleviates concerns about the condition being contagious between family members and others.”—Journal Reference-Michele L. Pearson, Joseph V. Selby, Kenneth A. Katz, Virginia Cantrell, Christopher R. Braden, Monica E. Parise, Christopher D. Paddock, Michael R. Lewin-Smith, Victor F. Kalasinsky, Felicia C. Goldstein, Allen W. Hightower, Arthur Papier, Brian Lewis, Sarita Motipara, Mark L. Eberhard. Clinical, Epidemiologic, Histopathologic and Molecular Features of an Unexplained Dermopathy. PLoS ONE, 2012; 7 (1): e29908 DOI: 10.1371/journal.pone.0029908
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    Protect public access to research in the U.S.
     
    Protect public access to research in the U.S There’s a bill before Congress called the Research Works Act that if passed could reverse the popular and successful NIH open access policy and block similar developments at other federal agencies. In a recent New York Times Opinion Piece, PLoS co-founder Mike Eisen argued that rather than “rolling back public access, Congress should move to enshrine a simple principle in United States law: if taxpayers paid for it, they own it”. We urge you to contact your representative and let them know that you oppose this retrograde step – simple guidelines (template letters, contact information) are available from the Alliance for Taxpayer Access.
    http://www.plos.org/protect-public-access-to-research-in-the-u-s/
    Public Access Being Denied To CAM and Alternative Health
    [1]Congress wants to limit your access to research—even though your tax dollars paid for it. If this bill passes, you’ll learn only what mainstream medicine wishes you to know. Action Alert! [2]–In 2008, the National Institutes of Health required that all federally funded research publications be made openly available. PubMedCentral [3] (PMC) is a free full-text archive of biomedical and life sciences journal literature at the National Institutes of Health’s National Library of Medicine.—The publishers of the journals weren’t so happy with this new arrangement—they were afraid no one would pay for their publications if the research results were immediately accessible. So the government agreed to give them a full year of journal sales before their research papers had to be posted on PMC, which lets them keep their subscriber base. Journal subscriptions to educational and medical institutions are expensive—and they’re big business.—But even this generous arrangement isn’t good enough for the Association of American Publishers (AAP). The trade group liked the old rules, where they could sell the tax-funded research back to the taxpayers. So the AAP got two members of Congress, Rep. Carolyn Maloney (D-NY) and Rep. Darrell Issa (R-CA), to introduce HR 3699 [4], the Research Works Act, just before the end of 2011.—This bill would prevent the NIH or any other agency from causing or even allowing private-sector research work to be disseminated online without prior consent of both the publisher and the study authors—even if the funding came from our tax dollars.–The AAP weren’t the only publishers involved. Elsevier—the Reed Elsevier Publishing Group, a multinational company that publishes around 2,000 journals and close to 20,000 books and major reference works—happens to be in Rep. Carolyn Maloney’s district, and Elsevier employees made campaign contributions to both Issa and Maloney [5]. (Apparently, it only takes $10,500 to buy two members of Congress.)–Said contributors all work for Tom Reller, vice president for global corporate relations at Elsevier. Interestingly, an email about the bill from Rep. Maloney to one of her critics contained language that was nearly identical [6] to language used by Reller when he was defending the same bill! Are members of Congress employing lobbyists as ghostwriters now?—This is about access to peer-reviewed scientific information—research that we pay for with our tax money. If this bill passes, Americans who want to read the results of federally funded research will have to buy access to each journal article individually—at a cost of $15 or $30 apiece. In other words, as the New York Times recently noted [7], taxpayers who already paid for the research would have to pay again to read the results.—Access to peer-reviewed scientific research is essential if you are to make informed choices regarding your family’s health—especially if you choose complementary and alternative medicine. Good research will let us choose wisely when it comes to questions of treatment modalities, vaccines, diet, nutrition, and medicine. Right now, supplement companies aren’t even allowed to tell you about the science behind their products [8], so we must get the scientific information directly from the source.–But that’s just the problem: consumers, integrative doctors, and small businesses might not have the funds to access all these scientific journals—which means your access to the science behind natural products will be limited to what mainstream medicine may wish you to know.—PMC compiles entire studies and has 2.3 million articles going back to 1965. It allows patients, physicians, students, teachers, and advocacy organization like ANH-USA to read about and cite the discoveries that our tax dollars paid for—to keep you informed in these pages, we may review as many as a hundred studies every year. If we needed to pay a publishing company every time we viewed a study which taxpayers have already paid for, we’d be giving thousands of dollars to a publishing company every year instead of protecting your access to natural health.
    So what can you do? Two things will make a huge difference!
    First, help us gain co-sponsors for the Free Speech about Science Act (FSAS) [9]. This landmark legislation enables the natural health products community to share peer-reviewed scientific findings about natural health products with the public. The problem, of course, is that if it becomes more difficult for supplement companies and consumers to access the scientific studies themselves, the entire point of FSAS is effectively undermined.
    The second step is to ask Congress to defeat this new Research Works Act. Please send your message today and explain why limiting access to the results of important studies—which your tax dollars have already paid for—is such a terrible idea. Take action immediately! [
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    Man Eats Food Only Advertised on TV, Becomes Hormonal
    Written by Colleen Vanderlinden
    Sit through any prime-time television show, televised sporting event, or even cartoon and you’re sure to see plenty of commercials for food. And you’ve undoubtedly noticed that this food runs the gamut from fast food pizza and burgers, to snack foods, to sugary breakfast fare. They are really “edible food-like substances,” as Michael Pollan would say.—What would a month of living solely on these TV commercial foods look like? And how would you feel at the end of it?—Tom Lamont, a writer for The Observer, decided to give it a try. For one month, he could only purchase and eat those foods he’d seen advertised on television. As we all well know, this means processed, sugary, salty, fatty food. They don’t advertise Brussels sprouts on television. No bulk whole grains. No pastured meat. Only those products that have a large advertising budget behind them.—Here are a few quotes from Lamont’s article, in which he details the experiment:—The pizza was a tactical move. Some 60 hours in I’d noted first signs of slowing down mentally – afternoons harder to work through, getting out of bed more of an undertaking. I’d decided the greasy stuff-in-a-bun was to blame, and that pizzas would be better. After all, weren’t those pureed tomatoes atop each slice? Real mushrooms and greens?—Upon which, he learns that pizza was possibly the worst choice he could have made.–By the time I got to Octomom I was starting to wonder what Aptamil “follow-on milk” might taste like.—At the end of a particularly bleak day my girlfriend saw fit to stage an intervention, ambushing me with a rule-breaking plate of salmon and beans for dinner. Was I imagining it, in the aftermath of the meal, when I immediately started to feel better? “No, no,” Briffa assured me, “these things can be incredibly immediate. It’s a bit like stopping smacking yourself in the face with a polo mallet. Immediately there’s relief.”—Basically, by the time the month was up, Lamont felt like a sluggish, cranky mess. Surprisingly, he didn’t gain any weight, but that could be at least partially because he got so tired of processed foods that he just didn’t eat as much after a while.–This is why those of us who are trying to eat better are often advised to shop the “perimeter” of the grocery store. The dairy, produce, meat, and bulk grain bins are often in the outer aisles. The inner aisles, and those attention-grabbing end caps, are the domain of processed food.–Moral of the story: shop the perimeter, grow a garden, and if something is advertised on TV, it’s probably not all that good for you!—Read more: http://www.care2.com/causes/man-eats-food-only-advertised-on-tv-becomes-hormonal.html#ixzz1kcyExqYc
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    Canada a World Leader in Genetically Modified Animal Biotechnology
    The development of the “Enviropig” pig and the “Aqua advantage” salmon gives Canada the dubious distinction of being a world leader in the creation of genetically modified animals for human consumption.
    The “Enviropig” has been cleared by Environment Canada and is currently waiting approval from Health Canada for human consumption. The University of Guelph, creator of the “Enviropig” released this information. Canadian government departments are not required to release information regarding approval applications, and don’t. To date, we don’t know if the approval of the “Aqua Advantage” for human consumption in Canada has been made or not. That has prompted Fin Donnelly, NDP critic of fisheries and oceans to table a motion in March of this year that the government make approval applications for the human consumption of genetically modified salmon and other aquatic life be transparent, and that the GM salmon specifically not be approved until studies are completed on the effects to human health, ecosystems, habitats and marine species.—The “Enviropig” was developed at the University of Guelph, which holds patents on the technology in the United States and Canada. Ontario Pork has the exclusive license to distribute the pig to swine breeders and producers worldwide. The Ontario and Canadian governments supported the research through research agreements and grants.–The “Enviropig” is a Yorkshire pig that has been genetically engineered with an E-coli bacteria phytase gene[U12] and a mouse promoter gene sequence. This change allows the pig to digest more phosphorus, with the result that there can be up to 70% reduction in phosphorus in the pig feces. Phosphorus in the feces is an environmental concern for factory farms because their runoff ends up in the water systems and promotes algae growth. This reduces oxygen in the water, and can kill a lot of the marine life. The algae can poison the water, and kill animals that drink from it. There are other cost effective ways to reduce phosphorus content in pig feces. These include adding a phytase supplement, [U13]and changing the feed composition. As well as waiting for human consumption approval in Canada, applications have been made to the FDA in the United States, and for licensing agreements in China.—AquaBounty is a company based in Massachusetts with its research facility in Prince Edward Island. The technology for the “Aqua Advantage” genetically modified Atlantic salmon was developed by the Memorial University of Newfoundland. This salmon contains a Chinook salmon growth hormone driven by the ocean pout antifreeze promoter. This alteration creates fish that are fully grown for market in 18 months instead of three years. The plan is for the eggs to be shipped from PEI to Panama to be grown, and then shipped to the States to be eaten. The fish are supposed to be completely infertile, and never escape. However, if some happened to be fertile, and happened to escape, it is thought that by escaping in Panama the fish would not survive, or be able to migrate to other salmon populations and contaminate them. The FDA has held hearings as to whether these fish are safe for human consumption, and the decision is pending. The FDA is also to produce an environmental impact study. There are two bills in Congress on this issue. One calls for the ban of GM salmon. The other requires the fish to be labelled transgenic in the event that the FDA approves them.—-The effect on human health from eating genetically modified animals isn’t known. Some scientists think they may affect the immune system and cause more allergies. The GM salmon has the added concern of possible effects on ecosystems where they are grown, and on wild salmon populations if they escape. Experiments have shown that genetically modified males are more successful mating, but produce fewer offspring. This is called the Trojan Gene Effect, and could lead to the extinction of the wild populations.—Although there is a debate as to whether GM animals are safe to eat or not, there should be no question that Canadians are entitled to know when applications are made for the human consumption of these animals, and the results of these applications. In the event they are approved, the food products should be labelled as transgenic, so people are aware of what they are eating.More info can be found at the Canadian Biotechnology Action network, Council of Canadians, and the Coastal Alliance for Aquaculture Reform websites.
     
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    [U1]It is beginning Again this time it is starting in Australia and now it will be heading throughout the Commonwealth—Canada-New Zealand-USA-UK—And any other territory of the Queen—seems to me the Global undermining is beginning and Supplements and Herbs have always been undr the attack of opportunist who want to control what is growing in the planet this is why Monsanto started to patent seeds so they can eventually patent all plant life—Not sure how much longer the Human Race will tolerate the Undermining of Life
    [U2]Friends OF Science and MEDICINE!! Wow can you actually believe they call this a Science—Medicine equates to disarming the Human Being—so I guess this is a dark science which this FDA/CODEX/AGENDA 21 Group is using Australia to Undermine
    [U3]Be prepared they are now going to limit access online to the studies and eventually will see them all but disappear—and this is the preliminary effect to take away the teaching –there are some many scientific Sites everywhere that to say there is no science based information on it ais at best wishful thinking
    [U4]Now why would they beso concerened about rebate moneys??? Do you think the money then would go into the pocket of the campaigners?
    [U5]Is this not interesting a Professor in a University—I wonder if this fellow is a Jesuit—or an agent of alien influence—I can see it now indigenious cultures being exterminated for this Earthy Knowledge
    [U6]You think maybe there is a Global Agenda to Debilitate people further
    [U7]Evidence Based—him Google Scholar—Quertle.Pub Med NIH—wonder if these are Evidenced Based!?
    [U8]Interesting—how can you not see and environmental connection—chemtrails-GMO= Outgrowth of a deadly pathogen inflicting the Globe
    [U9]Well what do you know So far they have it right —it is contributed to chemtails and GMO’s—so the infection would not be by the normal means
    [U10]From Clothes???other DEBRIS!!”” Read Between the lines here –they are telling you it is a fibred material they are not saying where it is really coming from
    [U11]In other words you are not going to be treated–
    [U12]A Fecal Gene ( S$%^)
    [U13]Phytase removes minerals from the body
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    Show of the Week February 6 2012
    Floater Solution
    Grape Seed Extract Kills Head and Neck Cancer Cells, Leaves Healthy Cells Unharmed
    Grape-Seed Extract Kills Laboratory Leukemia Cells, Proving Value Of Natural Compounds
     
    Grape Extracts May Be Effective Against Harmful Gut Bacteria
     
    How to Make Grapeseed Extract
     
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    Floater Solution
    Take 8 oz of water add 1 tsp of sea salt and add 1 tsp of Colloidal silver –preferably around 70ppm + ( I am using about 120-130 ppm) add to the water—and salt—shake well and make sure it is all dissolved—pour into a container that you can place eye into or a shot glass and allow the eye to be washed with this—open and close eyes and roll the eyes left to right and right to left—
    This will sting the eyes somewhat-but nothing dramatic—and you may see the floaters pop out of the eyes—
    The salt allows the eyes to clean and clear out what is in the cells and the silver allows the eyes to be free of the pathogens that may attack and increase a bio film in the eyes
     
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    Grape Seed Extract Kills Head and Neck Cancer Cells, Leaves Healthy Cells Unharmed
    ScienceDaily (Jan. 27, 2012) — Nearly 12,000 people will die of head and neck cancer in the United States this year and worldwide cases will exceed half a million.–A study published this week in the journal Carcinogenesis shows that in both cell lines and mouse models, grape seed extract (GSE) kills head and neck squamous cell carcinoma cells, while leaving healthy cells unharmed.–“It’s a rather dramatic effect,” says Rajesh Agarwal, PhD, investigator at the University of Colorado Cancer Center and professor at the Skaggs School of Pharmaceutical Sciences.–It depends in large part, says Agarwal, on a healthy cell’s ability to wait out damage.–“Cancer cells are fast-growing cells,” Agarwal says. “Not only that, but they are necessarily fast growing. When conditions exist in which they can’t grow, they die.”–Grape seed extract creates these conditions that are unfavorable to growth. Specifically, the paper shows that grape seed extract both damages cancer cells’ DNA (via increased reactive oxygen species) and stops the pathways that allow repair (as seen by decreased levels of the DNA repair molecules Brca1 and Rad51 and DNA repair foci).–“Yet we saw absolutely no toxicity to the mice, themselves,” Agarwal says.–Again, the grape seed extract killed the cancer cells but not the healthy cells.–“I think the whole point is that cancer cells have a lot of defective pathways and they are very vulnerable if you target those pathways. The same is not true of healthy cells,” Agarwal says.–The Agarwal Lab hopes to move in the direction of clinical trials of grape seed extract, potentially as an addition to second-line therapies that target head and neck squamous cell carcinoma that has failed a first treatment. –This work was supported by the R01 grants AT003623 from the National Center for Complementary and Alternative Medicine and CA91883 from the National Cancer Institute, NIH.–Story Source-The above story is reprinted from materials provided by University of Colorado Denver. –Note: Materials may be edited for content and length. For further information, please contact the source cited above.—Journal Reference–S. Shrotriya, G. Deep, M. Gu, M. Kaur, A. K. Jain, S. Inturi, R. Agarwal, C. Agarwal. Generation of reactive oxygen species by grape seed extract causes irreparable DNA damage leading to G2/M arrest and apoptosis selectively in head and neck squamous cell carcinoma cells. Carcinogenesis, 2012; DOI: 10.1093/carcin/bgs019
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    Grape-Seed Extract Kills Laboratory Leukemia Cells, Proving Value Of Natural Compounds
     
    ScienceDaily (Dec. 31, 2008) — An extract from grape seeds forces laboratory leukemia cells to commit cell suicide, according to researchers from the University of Kentucky. They found that within 24 hours, 76 percent of leukemia cells had died after being exposed to the extract.-The investigators, who report their findings in the January 1, 2009, issue of Clinical Cancer Research, a journal of the American Association for Cancer Research, also teased apart the cell signaling pathway associated with use of grape seed extract that led to cell death, or apoptosis. They found that the extract activates JNK, a protein that regulates the apoptotic pathway. While grape seed extract has shown activity in a number of laboratory cancer cell lines, including skin, breast, colon, lung, stomach and prostate cancers, no one had tested the extract in hematological cancers nor had the precise mechanism for activity been revealed.–“These results could have implications for the incorporation of agents such as grape seed extract into prevention or treatment of hematological malignancies and possibly other cancers,” said the study’s lead author, Xianglin Shi, Ph.D., professor in the Graduate Center for Toxicology at the University of Kentucky.–“What everyone seeks is an agent that has an effect on cancer cells but leaves normal cells alone, and this shows that grape seed extract fits into this category,” he said.–Shi adds, however, that the research is not far enough along to suggest that people should eat grapes, grape seeds, or grape skin in excess to stave off cancer ( Look At Foot Note the only thing to really consume is the seed ). [U1]”This is very promising research, but it is too early to say this is chemo-protective.”—Hematological cancers – leukemia, lymphoma and myeloma –Given that epidemiological evidence shows that eating vegetables and fruits helps prevent cancer development, Shi and his colleagues have been studying chemicals known as proanthocyanidins in fruits that contribute to this effect. Shi has found that apple peel extract contains these flavonoids, ( which you may want to consume if you know the tree is free and clear of unwanted chemicals) which have antioxidant activity, and which cause apoptosis in several cancer cell lines but not in normal cells. Based on those studies, and findings from other researchers that grape seed extract reduces breast tumors in rats and skin tumors in mice, they looked at the effect of the compound in leukemia cells.–Using a commercially available grape seed extract, Shi exposed leukemia cells to the extract in different doses and found the marked effect in causing apoptosis in these cells at one of the higher doses.—They also discovered that the extract does not affect normal cells, although they don’t know why.—The researchers then used pharmacologic and genetic approaches to determine how the extract induced apoptosis. They found that the extract strongly activated the JNK pathway, which then led to up-regulation of Cip/p21, which controls the cell cycle.–They checked this finding by using an agent that inhibited JNK, and found that the extract was ineffective. Using a genetic approach – silencing the JNK gene – also disarmed grape seed extract’s lethal attack in leukemia cells.–“This is a natural compound that appears to have relatively important properties,” Shi said.–Story Source-The above story is reprinted from materials provided by American Association for Cancer Research.
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    Grape Extracts May Be Effective Against Harmful Gut Bacteria
    ScienceDaily (Mar. 4, 2009) — In a new study researchers from Clemson University found various grape extracts and their compounds to be effective at inhibiting Helicobacter pylori, one of the leading causes of gastritis in humans. –H. pylori is the bacterial agent most commonly associated with peptic ulcers, gastritis, mucosa-associated lymphoid tissue lymphoma, and gastric cancer. Antibiotic therapy has proven effective at providing initial relief, however resistance can develop over time and relapse can occur. Previous studies have examined other natural plant extracts with anti-H. pylori activity such as garlic, broccoli, cranberries and green tea, however, grapes have yet to be evaluated despite being well known for their high levels of antioxidants and polyphenols.–The antibacterial effects of extracts from red, white, black and muscadine grapes as well as the pure compounds resveratrol, ellagic acid, and myricetin were tested for anti-H. pylori activity using agar dilution, laser scanning microscopy and cell proliferation. Following 24 hour treatment, results showed that muscadine grape skin extract had the highest anti-H. pylori effect, followed by muscadine grape synergy and seed extract. Additionally, two of the three compounds, resveratrol and ellagic acid, also inhibited H. pylori.–“In this study, grape extracts and their compounds were effective at inhibiting H. pylori in vitro, with highest efficacy by muscadine grape skin extract,” say the researchers.—Story Source-The above story is reprinted from materials provided by American Society for Microbiology. -Journal Reference-Brown et al. Antibacterial Effects of Grape Extracts on Helicobacter pylori. Applied and Environmental Microbiology, 2008; 75 (3): 848 DOI: 10.1128/AEM.01595-08
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    How to Make Grapeseed Extract
    A hundred years ago, seeds were pressed in a manual wedge press to extract the precious oil from grape seeds. Today, pharmaceutical-grade extracts often are made by combining high heat and solvents to the method. Small wineries and and other companies apply steam distillation or cold pressing to extract oils from grape seeds before grinding. The process is organic and requires minimal heat and no chemicals. You also can make organic grape seed extract for your personal use. You can benefit from the grape seed oil by-product if you have a lot of grapes or a small vineyard, a cold press and a grinder.
    Difficulty:
    Moderate
    Instructions
    Things You’ll Need
    Grape seeds
    Cold press machine
    Oil bottles
    Grinder
    Empty gel capsules
    Supplement bottles
    1.
    Remove the seeds and skin of the grapes while making your grape juice or other grape product. If you are doing this by hand, use a strainer.
    2 Wash the filtered grape extracts thoroughly.
    3 Set aside the extracted grape seeds and skin to dry for approximately 24 hours. During this time you can cook the seeds at a very low temperature, if desired. Cold pressing is an extraction process using minimal heat to extract oil out of seeds, so it is not an essential step to heat seeds, but it was a method used to extract more oil out of grape seeds when folks manually cold pressed at home. Heating the seeds slowly will also quicken the drying process.
    4 Remove the excess oil and juices from the grape seeds and skin by adding the grape extracts to your cold press. Press the extracts until the oil shows a visible separation from the solids. Set aside, and in time the oil will separate from the extracts even further.
    5 Skim the remaining oil from the solids.
    6 Save the pressed oil and preserve it in bottles for both therapeutic and culinary uses.
    7 Separate the grape seeds from the remaining skin solids.
    8 Dry the separated extracts to make them ready for grinding.
    9 Start grinding. Grind both the dried seeds and skins separately in a grinding appliance. Grind extracts until they form a fine powder. Combine the powdered seed extract with the powdered skin extract unless you prefer separate supplements of both seed and skin extract.
    10 Fill individual empty gelatin capsules with your powdered mixture. Large-size capsules in size 00 are a good size to start with.
    11 Preserve the capsules in a bottle and store in a cool location out of direct sunlight. Store powder in airtight bottles if you do not have gel caps.
    Tips & Warnings
    If you do not have access to plenty of grapes but wish to make your own organic extract, consider purchasing bulk grape seeds from wholesale suppliers. The dried grape seeds will be ready for cold pressing and grinding.
    Although the skins of fruits, vegetables and berries are valued for their nutrient dense concentration, it is not essential to use grape skins when making grape seed extract.
    Gelatin capsules are easy to use, come in varying sizes and can be found at many online health stores at affordable prices.
    Gelatin capsule ingredients consist of beef gelatin, glycerite and water. Suppliers often sell vegetable gel caps as well. Make sure you know which type you are buying if you are vegetarian.
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    TOP B
    [U1]Only if you grow your own grapeseed and do not spray—this is one of those re hashed articles and when you read this kind of stuff this implies there researcher does not know enough to understand the nature of GMO or Sprays that don’t wash off and can actually activate by the sugar one consumes from these skins
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    HOME
     
    Show of the Week February 10 2012
     
    Politics, Corporate Profits, Power & People – Health Canada & other FDA Abuses
    Urban farming gets a boost
    Tax ‘toxic’ sugar, doctors urge–Age restriction for sugary drinks proposed
     
    Poles protest ACTA online and on the streets
     
    Borax- Near Miracle Medicine Unknown
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    Politics, Corporate Profits, Power & People – Health Canada & other FDA Abuses
    When an insider breaks ranks with pharmaceutical orthodoxy, it is time to take notice. A concerned talks about what goes on behind the scenes, but the article that follows might be well worth readers’ consideration before standing in line for their next prescription refill. – Andrew W. Saul, OMNS Editor—I’m a registered pharmacist. I am having a difficult time with my job. I sell people drugs that are supposed to correct their various health complaints. Some medicines work like they’re supposed to, but many don’t. Some categories of drugs work better than others. My concern is that the outcomes of treatment I observe are so unpredictable that I would often call the entire treatment a failure in too many situations.
    How It Started
    In 1993, I graduated with a BS in Pharmaceutical Sciences from University of New Mexico. I became pharmacy manager for a small independent neighborhood drug store. Starting in the year 2000, nutrition became an integral part of our business. The anecdotal feedback from the customers who started vitamin regimens was phenomenal. That same year, my PharmD clinical rotations began with my propensity for nutritional alternatives firmly in place in my mind. On the second day of my adult medicine rotation, my preceptor at a nearby hospital informed me that he had every intention of beating this vitamin stuff out of me. I informed him that probably wouldn’t happen. Three weeks later I was terminated from my rotations. The preceptor told my supervisor at UNM that there were acute intellectual differences that couldn’t be accommodated in their program. What had I done? I was pressuring my preceptor to read an article written by an MD at a hospital in Washington state that showed if a person comes into the emergency room with a yet to be diagnosed problem and is given a 3,000-4,000 mg bolus of vitamin C, that person’s chance of dying over the next ten days in ICU dropped by 57%! [1]—One would think that someone who is an active part of the emergency room staff might find that an interesting statistic. His solution to my attempting to force him to read that article was having me removed from the program.
    Pecking Order–The traditional role of the pharmacist in mainstream medicine is subordinate to the doctor. The doctor is responsible for most of the information that is received from and given to the patient. The pharmacist’s responsibility is to reinforce the doctor’s directions. The doctor and the pharmacist both want to have a positive treatment outcome, but there is a legally defined ‘standard of care’ looking over their shoulder.—The training that I received to become a PharmD motivated me to become more interested in these treatment outcomes. After refilling a patient’s prescriptions a few times, it becomes obvious that the expected positive outcomes often simply don’t happen. It’s easy to take the low road and blame it on “poor compliance by the patient.” I’m sure this can explain some treatment failure outcomes, but not all. Many (indeed most) drugs such as blood pressure regulators can require several adjustments of dose alternative medicines before a positive outcome is obtained. or combination with
    Wrong Drug; Wrong Disease—One drug misadventure is turning drugs that were originally designed for a rare (0.3% of the population) condition called Zollinger-Ellison syndrome into big pharma’s treatment for occasional indigestion. These drugs are called proton-pump inhibitors (PPI). [2] After prolonged exposure to PPIs, the body’s true issues of achlorhydria start to surface. [3]–These drugs are likely to cause magnesium deficiency, among other problems. Even the FDA thinks their long-term use is unwise. [4]—The original instructions for these drugs were for a maximum use of six weeks . . . until somebody in marketing figured out people could be on the drugs for years. Drug usage gets even more complicated when you understand excessive use of antibiotics could be the cause of the initial indigestion complaints. What you get from inserting proton pump inhibitors into this situation is a gastrointestinal nightmare. A better course of medicine in this type of case might well be a bottle of probiotic supplements (or yogurt) and a few quarts of aloe-vera juice.—Many doctors are recognizing there are problems with overusing PPI’s, but many still don’t get it. An example of this is my school in NM had a lot of students going onto a nearby-impoverished area for rotations. They have blue laws in this area with no alcohol sales on Sunday. The students saw the pattern of the patients going into the clinics on Monday after abusing solvents, even gasoline vapors, and having the doctors put them on omeprazole (eg. Prilosec), long term, because their stomachs are upset. This is medicine in the real world.
    Reliability or Bias?—–Mainstream medicine and pharmacy instill into their practitioners from the beginning to be careful about where you get your information. Medical journals boast of their peer review process. When you discuss with other health professionals, invariably they will ask from which medical journal did you get your information. I actually took an elective course in pharmacy on how to evaluate a particular article for its truthfulness. The class was structured on a backbone of caution about making sure, as one read an article, that we understand that real truthfulness only comes from a few approved sources.–I was never comfortable with this concept. Once you realized that many of these “truthfulness bastions” actually have a hidden agenda, the whole premise of this course became suspect. One of my preceptors for my doctoral program insisted that I become familiar with a particular medical journal. If I did, she said, I would be on my way to understanding the “big picture.” When I expressed being a little skeptical of this journal, the teacher told me I could trust it as the journal was non-profit, and there were no editorial strings attached.
    Weirdly enough, what had started our exchange over credibility was a warm can of a diet soft drink on the teacher’s desk. She drank the stuff all day. I was kidding around with her, and asked her if she had seen some controversial articles about the dangers of consuming quantities of aspartame. She scoffed at my conspiracy-theory laden point of view and I thought the subject was closed. The beginning of the next day, the teacher gave me an assignment: to hustle over to the medical library and make sure I read a paper she assured me would set me straight about my aspartame suspicions, while simultaneously demonstrating the value of getting my information from a nonprofit medical journal. It turned out that the article she wanted me to read, in the “nonprofit medical journal,” was funded in its entirety by the Drug Manufacturers Association.
    Flashy Pharma Ads–As I read the literature, I discovered that there is very decided barrier between two blocks of information: substances that can be patented vs. those substances that can’t be. The can-be-patented group gets a professional discussion in eye-pleasing, four-color-print, art-like magazines. This attention to aesthetics tricks some people into interpreting, from the flashy presentation method, that the information is intrinsically truthful.[U1]—The world’s drug manufacturers do an incredibly good job using all kinds of media penetration to get the word out about their products. The drug industry’s audience used to be confined to readers of medical journals and trade publications. Then, in 1997, direct-to-consumer marketing was made legal. [5]—Personally, I don’t think this kind of presentation should be allowed. I have doctor friends that say they frequently have patients that self-diagnose from TV commercials and demand the doctor write them a prescription for the advertised product. The patients then threaten the doctor, if s/he refuses their request, that they will change doctors to get the medication. One of my doctor friends says he feels like a trained seal.[U2]
    Negative Reporting on Vitamins—A vitamin article usually doesn’t get the same glossy presentation. Frequently, questionable vitamin research will be published and get blown out of proportion. A prime example of this was the clamor in the press in 2008 that vitamin E somehow caused lung cancer. [6]
    I studied this 2008 experiment [7] and found glaring errors in its execution. These errors were so obvious that the experiment shouldn’t have gotten any attention, yet this article ended up virtually everywhere. Anti-vitamin spin requires this kind of research to be widely disseminated to show how “ineffectual” and even “dangerous” vitamins are. I tracked down one of the article’s original authors and questioned him about the failure to define what kind of vitamin E had been studied. A simple literature hunt shows considerable difference between natural and synthetic vitamin E. This is an important distinction because most of the negative articles and subsequent treatment failures have used the synthetic form for the experiment, often because it is cheap. Natural vitamin E with mixed tocopherols and tocotrienols costs two or three times more than the synthetic form.–Before I even got the question out of my mouth, the researcher started up, “I know, I know what you’re going to say.” He ended up admitting that they hadn’t even considered the vitamin E type when they did the experiment. This failure to define the vitamin E type made it impossible to draw a meaningful conclusion. I asked the researcher if he realized how much damage this highly quoted article had done to vitamin credibility. If there has been anything like a retraction, I have yet to see it.
    Illness is Not Caused by Drug Deficiency—If you’ve made it this far in reading this article you have discerned that I’m sympathetic to vitamin arguments. I think most diseases are some form of malnutrition. Taking the position that nutrition is the foundation to disease doesn’t make medicine any simpler. You still have to figure out who has what and why. There are many disease states that are difficult to pin down using the “pharmaceutical solution to disease.” A drug solution is a nice idea, in theory. It makes the assumption that the cause of a disease is so well understood that a man-made chemical commonly called ‘medicine’ is administered, very efficiently solving the health problem. The reality though, is medicine doesn’t understand most health problems very well. A person with a heart rhythm disturbance is not low on digoxin. A child who is diagnosed with ADHD does not act that way because the child is low on Ritalin. By the same logic, a person with type II diabetes doesn’t have a deficit of metformin. The flaw of medicine is the concept of managing (but not curing) a particular disease state. I’m hard pressed to name any disease state that mainstream medicine is in control of.—Voltaire allegedly said, “Doctors are men who pour drugs of which they know little, to cure diseases of which they know less, into human beings of whom they know nothing.”
    References:
    1. Free full text paper at: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1422648/pdf/20021200s00014p814.pdf
    Also: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1422648/?tool=pubmed
    2. http://www.ncbi.nlm.nih.gov/pubmed/2777040 and http://www.ncbi.nlm.nih.gov/pubmed/1697548
    3. http://www.ncbi.nlm.nih.gov/pubmed/21509344 and http://www.ncbi.nlm.nih.gov/pubmed/21731913
    4. http://www.fda.gov/Safety/MedWatch/SafetyInformation/
    SafetyAlertsforHumanMedicalProducts/ucm245275.htm
    5. http://www.nejm.org/doi/full/10.1056/NEJMsa070502#t=articleResults
    6. Media example:
    http://seniorjournal.com/NEWS/Nutrition-Vitamins/2008/8-02-29-VitaminEMay.htm .
    OMNS’ discussion at: http://orthomolecular.org/resources/omns/v04n18.shtml
    7. Original article at:
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258445/?tool=pubmed or http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258445/pdf/AJRCCM1775524.pdf
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    Urban farming gets a boost
    The San Diego City Council has opted to whip out the Miracle-Gro for urban farms, voting this week on myriad changes that allow residents to raise goats and chickens on their property, while enabling groups to grow crops on vacant lots in commercial zones without having to cut through a thicket of red tape.–The changes came on a unanimous vote that Councilwoman Lorie Zapf called regulatory relief and Councilman Todd Gloria called common sense. “It’s going to add to the quality of life in our city,” Gloria said. “As we become denser and more vertical in our communities, were going to need more opportunities to expand urban agriculture and grow our own food where we can.” Under the new rules, residents in most houses can keep up to five chickens. If a coop is kept at least 15 feet from property lines, a resident can keep up to 15 chickens. If the coop is at least 50 feet from any residential structure, a resident can keep up to 50 chickens. Coops have to be predator proof, ventilated and clean, while providing at least 6 square feet per bird.—Roosters are still off limits.-Under the old rules, residents could keep up to 25 chickens, but they had to be kept at least 50 feet from residential structures. That effectively banned them.—Goats are now allowed at single family homes, though males must be neutered and the animals must be of the miniature variety. Goat products, such as milk and cheese, must be for personal consumption only.—Finally, beekeeping will now be allowed in single-family areas, though no more than two hives are allowed and they must be at least 15 feet from a neighbor’s home and 20 feet from a street, alley or sidewalk. Hives must be in a protected area and screens are required in most circumstances.—The move to streamline the bureaucratic problems that accompanied efforts to establish community farms evolved several years ago when a group of refugees wanted to till the soil at a vacant lot in the mid-city area. The New Roots Community Farm finally opened after repeated delays, but only after organizers paid about $40,000 in fees. Its success, however, has been marked by a 2010 visit from First Lady Michelle Obama and extensive media coverage, including a recent feature in The New York Times. The co-op now has more than 80 growers from a dozen countries.—The challenges faced in opening the farm led Gloria to start seeking changes in the city’s ordinances related to urban agriculture. “It put the issue of urban agriculture on the radar,” he said. After New Roots was planted, Gloria began hearing from others frustrated with San Diego’s rules. At a community coffee in 2009, he got an earful from a couple of North Park neighbors who were told they couldn’t keep a small number of chickens on their property. “They thought it was unfair. I agreed. I thought it was silly for our code compliance officers to have to spend all this time on chickens. It just didn’t seem appropriate to me.”–The city secured a $50,000 SANDAG grant last March that was to pay for staffers to research and craft a new urban agriculture ordinance. That ordinance came to the City Council on Tuesday.
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    Tax ‘toxic’ sugar, doctors urge–Age restriction for sugary drinks proposed
    Sugar is so toxic that it should be taxed and slapped with regulations like alcohol, some U.S. researchers argue. In a commentary published in Wednesday’s issue of the journal Nature, doctors from the University of California, San Francisco, say that rising global rates of major killers such as heart disease and Type 2 diabetes aren’t caused by obesity as commonly thought. Instead, obesity is a marker for those health problems, and sugar is the true culprit, Dr. Robert Lustig, Laura Schmidt and Claire Brindis said. “We recognize that societal intervention to reduce the supply and demand for sugar faces an uphill political battle against a powerful sugar lobby,” they wrote. Measures such as smoking bans in public places, the use of designated drivers and the addition of condom dispensers in public washrooms were also battlegrounds that are now taken for granted for public health, the authors said in calling for sugar regulations.–They suggested:
    Taxing “added sugar” — any sweetener containing fructose that is added to food in processing, including sugar-sweetened beverages and sugared cereal.
    Controlling the location and density of fast-food outlets and convenience stores around schools and offering incentives to open grocery stores and farmers’ markets.
    Limiting sales during the school day or designating an age limit to buy drinks with added sugar.[U1]
    The researchers said sugar meets four criteria for regulation that are largely accepted by public health experts and that were first applied to alcohol. Those criteria are pervasiveness in society, toxicity, potential for abuse and negative impact on society.–It has been suggested that sales of sugary foods and drinks be limited during the school day. —The American Beverage Association responded to the article by saying there’s a drink and portion size for every occasion and lifestyle.-“We believe providing more options — not taking them away — is a better solution to help parents and individuals choose beverages that are right for them and their families,” the beverage group said on its website. Dietitians generally encourage people to eat a healthy diet without focusing on a single nutrient.–There are several toxic substances, such as salt and trans fat, that affect health if you eat too much of them, said Dr. Arya Sharma, scientific director of the Canadian Obesity Network.–“I don’t think we can bring the whole question about obesity down to a simple substance like people eating too much sugar,” Sharma said in an interview from Lethbridge, Alta.-The discussion is valuable, but no one knows what the unintended consequences of regulating sugar might be, Sharma said.–“Changing lifestyle is more about changing your life than your style,” Sharma said. “We have to ask ourselves, are we prepared to change our lives? Which means spend less time on the road, perhaps less hours working, perhaps start cooking again, perhaps bring home economics back into school.”
    [U1]These things are such a waste of time—this is to pacify the sugar Companies and retailers who use the white powder to further addict people—total waste of time Sugar needs to be stopped it is one of the most lethal poisons we have ever been addicted to and as a result causes a high rate of heart failure do to insulin overload and mineral depletion—and feeds a host of diseases that would otherwise not exist—Cancer –fungi—yeast—mild—microbial—organ failure –brain damage—liver damage—over worked immune system
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    Poles protest ACTA online and on the streets
     
    WARSAW, Poland (AP) — Hundreds of people waged a street protest in Warsaw on Tuesday to protest the government’s plan to sign an international copyright treaty, while several popular websites also shut down for an hour over the issue.—Poland’s support for the Anti-Counterfeiting Trade Agreement, or ACTA, has sparked days of protest, including attacks on government sites, by groups who fear it could lead to online censorship.—Prime Minister Donald Tusk insisted Tuesday that his government will not give in to the protesters. He vowed that Poland will sign the international agreement, which is aimed at protecting intellectual property — like music and books — and products including pharmaceuticals and designer items. ACTA enjoys widespread support from the producers of music, movies and a range of goods enjoying copyright protections.—“There will be no concessions to brutal blackmail,”[U1] Tusk said at a news conference.—Several popular websites replaced their normal content with a statement about ACTA, including several that are popular with young people and carry a mix of celebrity news, jokes, funny photographs and other entertaining material.—One site, http://www.wykop.pl, said that “under the banner of fighting piracy and concerns about intellectual property, ACTA will limit the rights of each of us.”—At the street protest, held in front of a European Union office, people carried banners that said “Stop ACTA,” while some put tape over their mouths to signify their fears that ACTA will infringe on freedom of expression online.—An extremist right-wing group is planning a separate protest Wednesday to oppose ACTA.—However, an influential group representing authors and composers — known by its Polish acronym ZAiKS — has thrown its support behind ACTA. ZAiKS argued that ACTA will not hurt Internet freedom but protect the rights of creators. It said that Internet piracy is now robbing artists and the state treasury of hundreds of millions of zlotys (many millions of dollars) in income[U2].—ACTA shares some similarities with the hotly debated Stop Online Piracy Act in the U.S., which was shelved by lawmakers last week after Wikipedia and Google blacked out or partially obscured their websites for a day in protest.—In recent days, a group calling itself Anonymous attacked Polish government websites, leaving several paralyzed on Sunday and Monday. On Tuesday, most appeared to be working again, though the prime minister’s site was unreachable.–Still, Polish leaders are vowing to stick to plans to sign ACTA in Tokyo on Thursday.—ACTA has been negotiated by a number of industrialized countries that have been struggling for ways to fight counterfeiting and intellectual property theft — crimes that cause huge losses to the movie and music industries and many other sectors.—The far-reaching agreement would cover everything from counterfeit pharmaceuticals to fake designer handbags to online piracy. The United States signed ACTA in October in Tokyo along with seven other countries: Australia, Canada, South Korea, Japan, New Zealand, Morocco and Singapore.–Critics of ACTA accuse the negotiating countries of hammering out the agreement in secret and failing to consult with the broader societies along the way.—(This version CORRECTS Updates with the websites going dark; corrects style on spelling of group ZAiKS. This story is part of AP’s general news and financial services
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    Borax- Near Miracle Medicine Unknown
     
    CHEMICAL NAME: Sodium borate decahydrate (borax)
    Would you believe a common box of laundry soap could treat thousands of patients, relieving them of fluoride toxicity, removing fungus from their body, taking out joint pains, while cleaning their receptor sites for better insulin and thyroxine utilization ? Could this be the missing link for syndrome X, diabetes and hypothyroidism types II ?
    The same could be said true for many common, household and laboratory chemicals, but our profit crazed society prefers otherwise. However, we should become prepared for an imminent financial collapse, and we doctors should know these chemistries as a duty to uphold the Hippocratic Oath. Further, it could save our patients sufferings NOW.
    Read more…
    WARNING!!!
    DO NOT CONFUSE BORAX WITH BORIC ACID!
    DO NOT TAKE BORIC ACID IN PLACE OF BORAX!
    There is a lot of evidence why borax is effective against nearly all forms of fungal disease, whether they be mycoplasma found in lupus, rosacea, dog mange, interstitial cystitis, plasmodium parasites, Morgellon’s disease, or even pneumonia. I think borax medicine is one of the medicines most ignored, misinformed or even suppressed in our present society. The so-called medical authorities have done its propaganda so well that very few know that the toxicity of borax is about equal to that of simple table salt.
    I have seen patients suffering from sore throat and laryngitis. The cure is relatively simple: gargle with borax in water. Take note of our revered Dr. Boericke:
    A piece of borax, the size of a pea, dissolved in the mouth, acts magically in restoring the voice, in cases of sudden hoarseness brought on by cold, and frequently for an hour or so, it renders the voice silvery and clear. HOMŒOPATHIC MATERIA MEDICA by William BOERICKE, M.D.
    Below is one of the many interesting points concerning borax, which mentions the use of borax against fungus, a well known fact amongst microbiologists but totally unknown to the public.
    There is another facet about Borax, and that is the mineral element Boron which is able to clean the receptor sites of cell membranes. This is particularly important for diabetes type II and hypothyroidism type II.
    Boron administered during fluoride intoxication or after its interruption, reduces fluoremia and increases urinary fluoride excretion. So Twenty Mule Team Borax is our answer to de-intoxicate the body from poisoning by municipal water sources of which affects millions of people.
    Osteoarthritis. Developing research suggests that boron might be useful for decreasing symptoms of osteoarthritis.
    Improving thinking and coordination in older people. There is some evidence that taking boron by mouth might improve cognitive function and the ability to coordinate small muscle movements (fine motor skills) in older people.
    Increasing testosterone.
    Boron seems to affect the way the body handles other minerals such as magnesium and phosphorus. It also seems to increase estrogen levels in older (post-menopausal) women and healthy men. Estrogen is thought to be helpful in maintaining healthy bones and mental function.
    Boron supplementation can lower the amount of magnesium that is flushed out in the urine. This can lead to blood levels of magnesium that are higher than usual. Among older women, this seems to happen more often in women who do not get much magnesium in their diet. Among younger women, the effect appears to be greater in women who exercise less. No one knows how important this finding is to health, or whether it happens in men.
    ARTHRITIS; OSTEOPOROSIS; ANTI-AGING
    Try 1/8 teaspoon of borax in one liter of water/day. You just drink this water throughout the day. If it runs out then drink just normal water, with some magnesium added if possible. Magnesium found in the chloride form (see) is pre-digested. They seem to be synergistic with the vitamin D as vitamin D promotes calcium and the body needs to balance both magnesium and calcium to an ideal amount. So get some sunshine daily.
    NANO-BUGS: SKIN PROBLEMS; ATHLETE’S FOOT; BALDING; SCABIES
    Consider taking borax for mites, lice, scabies, etc. Some people believed the demodex mites are responsible for rosacea. They may be right. But, there are others too that are not yet identified. I prefer to lump all these insect issues to just one category: nanoinsects. These insects have several weakness that you can kill them, or at least weaken them. One obvious ones is borax. The treatment can be broken down to two things;
    1. Taken internally: Try 1/8 teaspoon (~250 MG.) of borax in one liter of water/day. You just drink or sip this water throughout the day. You can do this once or twice a week as a tonic. This will clean your cellular receptor sites for insulin and thyroxine.
    2. Used externally: Dog mange is confirmed demodex mites and the only treatment that effectively cured of dog mange is 1% hydrogen peroxide and borax saturated solution applied topically. Many people believe the demodex mites is the cause of rosacea. What I am sure about is it is an insect issue. The method of killing them is external application of 1% hydrogen peroxide with borax saturated solution to the face, unrinsed. It tends to cause drying. So you can apply appropriate lotions to prevent drying, such as jojoba oil, aloe vera or another oil or cream.
    3. Borax — The ultimate fungal killer. Take 1/8 teaspoon in a litre of water every day. Normally taken for 4 days, then 3 days off every week. 20 Mule Team Borax is fine for this. Borax also removes fluorine from the body.
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    [U1]Meaning the deal is done and we do not care what you think—and you really have NO RIGHTS OF FREEDOM
    [U2]Always the same BS –we are losing Money—what everyone should do is what w=hat was done too the rockstars that went after napster –boycott and not buy or support anything these @$$ holes are trying to do –infringe on expression
     
    [U1]This same Kind of Ad campaigning goes on in the Nutraceutical end as well with the imagery of the container looking like something coming out of a lab or doctors office—and a lot of times these same substances being sold in the health food industry are just fluff or prohibitively expensive and Do either very little or nothing at all other then bleed your wallet
    [U2]So here is where the Doctors should be banning to remove this kind of ad campaigning to get people off the idea of illegal drug use-via ad commercial and then write them a drug
    [U3]Only if you grow your own grapesd and do not spray—this is one of those re hashed articles and when you read this kind of stuff this implies there researcher does not know enough to understand the nature of GMO or Sprays that don’t wash off and can actually activate by the sugar one consumes from these skins
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    Show of the Week February 13 2012
     
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    The Effects of Taraxacum Officinale Extracts (TOE) Supplementation on Physical Fatigue in Mice
    Anti-influenza virus effect of aqueous extracts from dandelion.
    Recipe For Dandelion
    U.S. Law Allows Testing of Chemicals and Biological Agents on “Civilian Population”
    Glyphosate in Monsanto’s Roundup Impacting Global Health
     
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    The Effects of Taraxacum Officinale Extracts (TOE) Supplementation on Physical Fatigue in Mice.
    Jinchun Z, Jie C.
    Source–Department of Physical Education, Huangshi Institute of Technology, Huangshi, Hubei Province, 435003, PRC.
    Abstract—The study is to investigate the effect of Taraxacum officinale extracts (TOE) supplementation on physical fatigue based on the forced swimming capacity in mice. Forty Kunming male mice were randomly divided into 4 groups, i.e., normal control (NC) and three doses of TOE treated group (High-dose, Middle-dose and Low-dose). Three TOE treated groups were treated by oral TOE with 10, 30 and 100mg/kg b.w respectively for a period of 42 days. The normal control group was given a corresponding volume of sterile distilled water. After 6 weeks, the forced swimming capacity and blood biochemical parameters in mice were measured, and the result showed that TOE had an anti- physical fatigue effect. It enhanced the maximum swimming capacity of mice, effectively delayed the lowering of glucose in the blood, and prevented the increase in lactate and triglyceride concentrations.
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    Anti-influenza virus effect of aqueous extracts from dandelion.
    He W, Han H, Wang W, Gao B.
    Source–CAS Key Laboratory of Pathogenic Microbiology and Immunology (CASPMI), Institute of Microbiology, Chinese Academy of Sciences, 1 Beichen West Road, Beijing 100101, PR China. [email protected]
    ABSTRACT
    BACKGROUND–Human influenza is a seasonal disease associated with significant morbidity and mortality. Anti-flu Traditional Chinese Medicine (TCM) has played a significant role in fighting the virus pandemic. In TCM, dandelion is a commonly used ingredient in many therapeutic remedies, either alone or in conjunction with other natural substances. Evidence suggests that dandelion is associated with a variety of pharmacological activities. In this study, we evaluated anti-influenza virus activity of an aqueous extract from dandelion, which was tested for in vitro antiviral activity against influenza virus type A, human A/PR/8/34 and WSN (H1N1).–RESULTS—Results obstained using antiviral assays, minigenome assay and real-time reverse transcription-PCR analysis showed that 0.625-5 mg/ml of dandelion extracts inhibited infections in Madin-Darby canine kidney (MDCK) cells or Human lung adenocarcinoma cell line (A549) of PR8 or WSN viruses, as well as inhibited polymerase activity and reduced virus nucleoprotein (NP) RNA level. The plant extract did not exhibit any apparent negative effects on cell viability, metabolism or proliferation at the effective dose. This result is consistent with the added advantage of lacking any reported complications of the plant’s utility in traditional medicine over several centuries.—CONCLUSION-The antiviral activity of dandelion extracts indicates that a component or components of these extracts possess anti-influenza virus properties. Mechanisms of reduction of viral growth in MDCK or A549 cells by dandelion involve inhibition on virus replication.
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    RECIPE For Dandelion—take dried dandelion root or leaf and add 1-2 tablespoon in a percalotor—add 1 tsp of elderberry- add distilled water—and percolate this combo for 5 minutes –pour in a glass and drink several times a day—you can re add water to the percolator till the mix comes out clear or more transparent
     
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    U.S. Law Allows Testing of Chemicals and Biological Agents on “Civilian Population
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    Glyphosate in Monsanto’s Roundup Impacting Global Health
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    Show of the Week February 17 2012
     
    Hip fracture risk rises with acid reflux drug use
     
    Cholesterol and mortality – specific studies
     
    Coffee Consumption Reduces Fibrosis Risk in Those With Fatty Liver Disease
     
    How To Make A PVC Crisis Bow
     
    Antibacterial activity of essential oils from Eucalyptus and of selected components against multidrug-resistant bacterial pathogens
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    Hip fracture risk rises with acid reflux drug use
     
    Some older women are more likely to suffer debilitating hip fractures if they take certain indigestion drugs, U.S. researchers say.–The risk of hip fracture was 1.35 times higher among post-menopausal women who regularly took drugs used to treat heartburn and acid reflux for two years compared with those who did not take the medication.—The study published in Wednesday’s issue of the British Medical Journal followed nearly 80,000 postmenopausal women participating in the U.S. Nurses Health Study from 2000 to 2008. Since that project started in 1976, analysis of the nurses’ medical records and questionnaires every two years have provided insight into health and lifestyle risks for women ranging from breast cancer to alcohol use. The findings suggested that women who took the heartburn drugs, known as proton pump inhibitors, and smoked could face more than 1.50 times higher risk of fracture.–In May 2010, the U.S. Food and Drug Administration warned of hip fractures among those taking PPIs but concluded that more data was needed for a full analysis.—While several other studies have raised concerns about the long-term use of proton pump inhibitors and risk of hip fractures, the results were conflicting and many lacked information on important diet and lifestyle factors that could make a difference.–Proton pump inhibitors are among the most commonly used drugs worldwide, the researchers said.–Use of the drugs increased in the U.S. after they became available without a prescription.–In the latest study, Hamed Khalili of Massachusetts General Hospital and his co-authors took menopausal status, body weight, physical activity levels, smoking, alcohol consumption and use of calcium supplements into account in their analysis.–Hip fractures from low and moderate traumas such as falling on ice or off a chair were included. High traumas such as skiing accidents or falling down the stairs were not.
    Hip fracture risk fell after drugs stopped–Over the eight-year study period, there were 893 hip fractures among the participants.–Compared with use of proton pump inhibitors, regular use of a milder antacid called H2 blockers was tied to a “more modest” risk of fracture of 1.23 times higher, the researchers said.–Given that use of proton pump inhibitors is on the rise, the estimates suggest the drugs could be contributing to a “high burden of fractures,” they concluded.—The risk of hip fracture returned to normal two years after women stopped taking proton pump inhibitors, the researchers said.—The study’s authors acknowledged drawbacks of the study, such as not having specific information on the type or brand of proton pump inhibitors used. They didn’t confirm hip fractures against medical records, but said the nurses are extremely reliable at reporting the injuries.–The study was funded by the U.S. National Institutes of Health.
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    Cholesterol and mortality – specific studies
    The Honolulu Study(1) was a 20 year study of cholesterol levels and mortality in 3,572 Japanese American men. The study concluded that “Only the group with low cholesterol concentration at both examinations had a significant association with mortality”. The authors went on “We have been unable to explain our results”. (I.e. we were expecting lower cholesterol to equal lower mortality, not the other way round). –All credit to the team for their honest reporting of these unexpected results and their final statement in the abstract: “These data cast doubt on the scientific justification for lowering cholesterol to very low concentrations (<4·65 mmol/L) in elderly people.”–Framingham similarly concluded that “There is a direct association between falling cholesterol levels over the first 14 years and mortality over the following 18 years (11% overall and 14% CVD death rate increase per 1 mg/dL per year drop in cholesterol levels).”(2) Kendrick does a clever calculation on this quotation and translates this into – a reduction in cholesterol from 5 to 4 mmol/L would increase your risk of dying by 400%.—————Elaine Meilahn reported in Circulation (2005) “In 1990, an NIH (National Institutes of Health) conference concluded from a meta-analysis of 19 studies that men and, to a lesser extent, women with a total serum cholesterol level below 4.2 mmol/L exhibited about a 10% to 20% excess total mortality compared with those with a cholesterol level between 4.2 and 5.2 mmol/L. Specifically, excess causes of death included cancer (primarily lung and hematopoietic), respiratory and digestive disease, violent death (suicide and trauma), and hemorrhagic stroke.”(3)——————- In The Great Cholesterol Con, Dr Malcolm Kendrick analysed some World Health Organisation (WHO) data. The WHO has extensive data from almost 200 countries on more health measures than you could imagine – definitely worth a look one rainy afternoon. This is where Kendrick presented the world with two different Seven Country Studies. Kendrick took the seven countries with the lowest saturated fat intake and then the seven countries with the highest saturated fat intake. ——Cholesterol-lowering-enthusiasts may need to read this twice – but he found: “Every single one of the seven countries with the lowest saturated fat consumption has significantly higher rates of heart disease than every single one of the countries with the highest saturated fat consumption.”—As Kendrick’s two unbiased seven country studies showed – there is not even an association between saturated fat and heart disease – let alone causation. However, Keys published his Seven Country Study and the rest, as they say, is history.–The next chapter in The Great Cholesterol Con goes on to look at cholesterol and heart disease (and overall death rates) and quoted many great studies where it is shown that lower cholesterol is associated with higher mortality. However, it did leave me thinking – having run the data on saturated fat and heart disease, let’s just run all the data on the cholesterol and heart disease and get to the bottom of this hypothesis from all parts of the allegations.
    Cholesterol & Mortality
    It actually didn’t take that long – not even a couple of hours one Saturday afternoon. You go to the WHO statisitics area of their web site ( https://apps.who.int/infobase/Comparisons.aspx ) and then pick data for cholesterol from risk factors (how judgemental to start with) and then look under: Global burden of disease (mortality); All causes; Non communicable diseases and then G Cardiovascular disease (shortened to CVD). CVD deaths include ischemic heart disease and cerebrovascular disease – that means fatal heart attacks and fatal strokes to lay people. You find the most recent year where you can get both sets of data to compare like with like. This turns out to be 2002. You download their very user friendly spreadsheet data (CSV) – cut and paste it into a spreadsheet application and then try to remember how the heck to do scatter diagrams!–The WHO data is split into men and women. I first did the scatter diagrams for average (mean) cholesterol levels and CVD deaths. Then I ran the Pearson correlation coefficient on these numbers. This gives us the term called “r”. “r” tells us if there is some kind of a relationship: an r score of 0 would indicate no relationship; an r score of 1 would indicate a perfect relationship. A negative r score is called an inverse relationship e.g. the price of concert tickets is likely to be inversely related to the number of concert tickets bought – fewer tickets being bought at higher prices.
    The “r” score for men revealed that there was a small relationship of 0.13 – however this relationship was inverse. The diagram and correlation shows that higher cholesterol levels are associated with lower CVD deaths and lower cholesterol levels are associated with higher CVD deaths. In women, the relationship is stronger – to the point of being meaningful. The r score was 0.52 – but, again, inverse. For women, higher cholesterol levels are quite significantly associated with lower CVD deaths and lower cholesterol levels are quite significantly associated with higher CVD deaths. Please note that I have added r squared on the graphs below (the spreadsheet application can do this for us) and it can confirm that you’ve got your r numbers right and r squared tells us the strength of any relationship we have observed.—All you need to do is to look at the lines going down to the right and wonder how on earth we ever got away with telling people that cholesterol causes heart disease. High cholesterol is associated with lower heart disease and vice versa – for all the data available in the world. High cholesterol is not even associated with high heart disease, let alone does it cause it.
     
    It gets worse. I then kept the cholesterol information and changed the death rates to total deaths – all deaths from any cause – cancer, heart disease, diabetes, strokes – all deaths. You can see the diagrams for men and women again below. This time there is a significant relationship for both men and women: 0.66 for men and 0.74 for women – again inverse. There is a significant association between higher cholesterol levels and lower deaths and lower cholesterol levels and higher deaths for men and an even more significant relationship for women.
    I removed the outliers (obvious ‘off-the-line’ data points) and reran the data and it made not one iota of difference. With 192 data points showing such a strong trend, a couple, or a handful, of countries really makes NO difference. —
    This is serious. I’ve shown it to a couple of academics (Professor sort of things) with whom I’ve been having great debates, as I want to see what the view is from people who wholly believe the fat/cholesterol/heart/death hypothesis. (Kendrick talks in his book about what happened when he showed an intelligent colleague his two seven countries studies and the evidence was just dismissed instantly). It is most useful to know what the resistance arguments will be before starting to invite the resistance. The two arguments I got back were:
    1) “Ah yes – but this is only an association.”
    Ah yes – but a) we changed global dietary advice back in 1977-1983 on the back of an association in Seven (carefully hand picked) Countries that miraculously became a causation even when the association was far from established and b) it is an association that’s the opposite to the one that the world currently holds true and c) that’s what epidemiology is supposed to be about – establish an association and then investigate if there could be any causation or useful learnings. So, let us go out with a new paradox – that high cholesterol is associated with low deaths and then see what dietary advice emerges.
    2) “But that’s total cholesterol – the key thing is the ratio of good to bad cholesterol.”– The chemical formula for cholesterol is C27H46O. There is no good version or bad version. HDL and LDL are not even cholesterol, let alone good cholesterol or bad cholesterol. They are lipoproteins and they carry cholesterol, triglyceride, phospholipids and protein. [U1]— This also says to me – even though saturated fat has nothing to do with cholesterol, it doesn’t actually matter. Even if it did – cholesterol is only associated with CVD deaths in an inverse way. If fat did raise cholesterol – as public health officials like to claim – it could save lives! (Their words, not mine.)
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    Coffee Consumption Reduces Fibrosis Risk in Those With Fatty Liver Disease
     
    ScienceDaily (Feb. 2, 2012) — Caffeine consumption has long been associated with decreased risk of liver disease and reduced fibrosis in patients with chronic liver disease. Now, newly published research confirms that coffee caffeine consumption reduces the risk of advanced fibrosis in those with nonalcoholic fatty liver disease (NAFLD). Findings published in the February issue of Hepatology, a journal of the American Association for the Study of Liver Diseases, show that increased coffee intake, specifically among patients with nonalcoholic steatohepatitis (NASH), decreases risk of hepatic fibrosis.—The steady increase in rates of diabetes, obesity, and metabolic syndrome over the past 20 years has given rise to greater prevalence of NAFLD. In fact, experts now believe NAFLD is the leading cause of chronic liver disease in the U.S., surpassing both hepatitis B and C. The majority of patients will have isolated fatty liver which has a very low likelihood of developing progressive liver disease. However, a subset of patients will have NASH, which is characterized by inflammation of the liver, destruction of liver cells, and possibly scarring of the liver. Progression to cirrhosis (advanced scarring of the liver) may occur in about 10-11% of NASH patients over a 15 year period, although this is highly variable.—To enhance understanding of the correlation between coffee consumption and the prevalence and severity of NAFLD, a team led by Dr. Stephen Harrison, Lieutenant Colonel, U.S. Army at Brooke Army Medical Center in Fort Sam Houston, Texas surveyed participants from a previous NAFLD study as well as NASH patients treated at the center’s hepatology clinic. The 306 participants were asked about caffeine coffee consumption and categorized into four groups: patients with no sign of fibrosis on ultrasound (control), steatosis, NASH stage 0-1, and NASH stage 2-4.–Researchers found that the average milligrams in total caffeine consumption per day in the control, steatosis, Nash 0-1, and Nash 2-4 groups was 307, 229, 351 and 252; average milligrams of coffee intake per day was 228, 160, 255, and 152, respectively. There was a significant difference in caffeine consumption between patients in the steatosis group compared to those with NASH stage 0-1. Coffee consumption was significantly greater for patients with NASH stage 0-1, with 58% of caffeine intake from regular coffee, than with NASH stage 2-4 patients at only 36% of caffeine consumption from regular coffee.—-Multiple analyses showed a negative correlation between coffee consumption and risk of hepatic fibrosis. “Our study is the first to demonstrate a histopatholgic relationship between fatty liver disease and estimated coffee intake,” concludes Dr. Harrison. “Patients with NASH may benefit from moderate coffee consumption that decreases risk of advanced fibrosis. Further prospective research should examine the amount of coffee intake on clinical outcomes.”–Story Source—The above story is reprinted from materials provided by Wiley-Blackwell, via AlphaGalileo..—Journal Reference-Jeffrey W. Molloy, Christopher J. Calcagno, Christopher D. Williams, Frances J. Jones, Dawn M. Torres, Stephen A. Harrison. Association of coffee and caffeine consumption with fatty liver disease, nonalcoholic steatohepatitis, and degree of hepatic fibrosis. Hepatology, 2012; 55 (2): 429 DOI: 10.1002/hep.24731
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    How To Make A PVC Crisis Bow
     
    The young people of today spend less time learning to hunt and trap wild game or catch fish than generations of the past. The United States Fish and Wildlife Service conducted a survey about outdoor recreation that showed that between 2001 and 2006, 12 percent fewer people spent time fishing, and 4 percent fewer people spent time hunting. This is good news for trout and deer, but not such great news for society. Urbanization and electronic hobbies like video games and cable television shows are slowly taking the place of rural communities and outdoor recreation. Children involved in sports and other extracurricular activities have less time to spend learning about hunting and fishing – and parents shuffling them between events have less time to teach them.
    Another reason people are hunting less is because the equipment is not readily available or is too expensive. Too often, sporting goods stores cater more to team sports and outdoor activities like hiking or bicycling than they do hunting and fishing. High price tags attached to the quality products found on their shelves discourage some customers from even trying those types of sports in the first place. And some other stores only carry products related to hunting and fishing during certain times of the year, making it impossible to buy the supplies necessary for practicing those sports during the off-season.
    It’s the Hunt, Not the Kill
    For many hunters, including the ones in my own and my husband’s families, the sport is not about killing animals. It’s about hunting, and it’s about parents passing down the traditions they learned from their parents and grandparents. Responsive Management, an outdoor research group in Harrisonburg, Virginia, says that about 90 percent of kids who hunt do so because they grew up around adults who are hunting enthusiasts. My husband is a traditional archer, and one way that he inspired our sons to try the hobby was by helping them make their own bow hunting equipment. They recently found a YouTube video that showed how to turn a PVC pipe into an archery bow, and of course had to try it out for themselves.
    You might wonder why anyone would want to turn a piece of PVC pipe into a bow. First of all, it’s very economical. Prices for archery bows for a beginner or a child can start out as much as one hundred dollars or more. Higher quality equipment for serious hunters can run well over one thousand dollars. A PVC archery bow costs less than twenty dollars to make. It is a great bow for a beginner or a child because it is lightweight and easy to handle. And because the PVC construction is waterproof, it also makes a great tool for bow fishing.
    Building your own PVC archery bow will require trips to both hardware and farm supply stores for supplies. This product list and the following instructions are the ones my teenage sons followed. Instructions for a few different versions of a PVC archery bow exist online, but the ones on “The Mans Cave” website were extremely easy to follow. They even have a video that shows each step from start to finish. In addition to the instructions below, they also show how to make an arrow rest from PVC pipe. My sons had so much fun on this project that they’re now making them for friends and a few of their cousins.
    Materials Needed
    One 5′ section of schedule 40 PVC pipe, 3/4″ thick
    One 5′ section of schedule 40 PVC pipe, 1/2″ thick
    One 4′ 5″ section of fiberglass rod, 3/8″ thick
    Duct tape and electrical wrap
    Pipe insulation (for handle)
    One 55″ bowstring
    WD-40
    Spray paint (optional)
    Safety glasses
    Need to put meat on the table fast?
    Instructions
    Before starting any part of this project that involves cutting, filing, or sanding, please put on a pair of safety glasses. PVC shavings and dust flying about the air can easily cause damage to the eyes.
    Using a saw, cut a line down the one side of your 1/2″ thick PVC pipe. Try to keep the line as straight as possible.
    Spray the inside of both ends of your 3/4″-thick PVC pipe with WD-40.
    Spray the outside of your 1/2″-thick PVC pipe with WD-40.
    Force the 1/2″ thick PVC pipe into the 3/4″ thick section. You may have to push the pipe against the ground to force it all the way in. If you do this, please be careful because you do not want to snap your pipe in half. Keep pushing until the 1/2″-thick pipe is fully inserted into the 3/4″-thick one.
    Mark off 3/4″ from either side of the pipe.
    Using a 1/8″ drill bit, drill a hole on either side of the pipe right on the mark. Be sure the holes line up and are even on both sides at each end.
    Using a hacksaw, cut through the end of the pipe, stopping at the holes you drilled in the last step.
    Repeat this on the other end of the bow.
    Using a metal file, smooth down the inside of the cut to clean up any rough edges. You are going for a clean look during this step.
    Using rough grit sandpaper, smooth down the areas you just filed for a polished finish.
    Wipe your bow clean of any dust from the cutting and filing and use spray paint to decorate it however you want.
    Attach a piece of pipe insulation for a handle and, if you prefer to make it more permanent, duct tape it in place.
    Wrap the fiberglass rod with duct tape and then wrap it in a layer of electrical tape.
    Stick the fiberglass rod into the PVC pipes. This will help add pounds to your bow when you are shooting it.
    String it as you would a normal longbow, and you are ready to begin shooting. As I said before, quite a few variations of instructions for making a PVC archery bow exist online, both for longbow and recurve types. The instructions in this article are easy to follow, especially for a beginner or someone who cannot invest a lot of money into the project.
    Archery Accessories
    Some bow hunting accessories are optional, while hunters from all walks agree that others are mandatory for going out to spend a day in their favorite hunting area. What you take hunting is up to you, but here are some suggestions:
    Arm guard – A good arm guard costs less than twenty dollars, and not only do they protect your arm, but they also help you focus more on how accurate your arrow flies towards its intended target. If you’re handy with leather or just feeling brave, you can find instructions online for making your own.
    Bow socks – Made of soft cloth like fleece or flannel, a bow sock (or sometimes called a bow bag) prevents equipment from becoming scratched while in storage or being transported between your house and your favorite hunting spot. If either you or your significant other is at all handy with a sewing machine, try making one with fleece purchased at your local fabric store. Some sell fleece that is 68″ wide, which is the perfect size when making a bow sock for a 60″ PVC archery bow.
    Quiver – This is by far the best item for carrying your spare arrows. A quiver prevents accidental stabbings and helps to keep the feathers at the end of the arrow from getting ruffled. Websites like Etsy have custom-made quivers of materials like leather studded with medieval-looking steel plating, raccoon fur that harkens to the days of native America, oriental bamboo, and more. Even if you don’t plan to buy a quiver from the Internet, websites like Etsy are a great source of inspiration when looking for ideas for how to make your own items.
    Stringers – These pull the limbs of the bow evenly to allow the bowstring to loop over the tips of the bow. Using a bow stringer means the limbs are less likely to twist and thus cause damage to the bow.
    Targets – There’s nothing like practicing, whether during bow season or in the off months. You can find various types of printable bull’s-eye targets online for free. My husband and sons love sticking these on the side of a cardboard box, an old hay bale, or anything else that allows the arrow to safely enter without passing completely through.
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    Antibacterial activity of essential oils from Eucalyptus and of selected components against multidrug-resistant bacterial pathogens.
    Pharm Biol. 2011 Sep;49(9):893-9
    Authors: Mulyaningsih S, Sporer F, Reichling J, Wink M
    Abstract
    CONTEXT: Eucalyptus globulus Labill (Myrtaceae) is the principal source of eucalyptus oil in the world and has been used as an antiseptic and for relieving symptoms of cough, cold, sore throat, and other infections. The oil, well known as ‘eucalyptus oil’ commercially, has been produced from the leaves. Biological properties of the essential oil of fruits from E. globulus have not been investigated much.
    OBJECTIVE: The present study was performed to examine the antimicrobial activity of the fruit oil of E. globulus (EGF) and the leaf oils of E. globulus (EGL), E. radiata Sieber ex DC (ERL) and E. citriodora Hook (ECL) against multidrug-resistant (MDR) bacteria. Furthermore, this study was attempted to characterize the oils as well as to establish a relationship between the chemical composition and the corresponding antimicrobial properties.
    MATERIALS AND METHODS: The chemical composition of the oils was analyzed by GLC-MS. The oils and isolated major components of the oils were tested against MDR bacteria using the broth microdilution method.
    RESULTS: EGF exerted the most pronounced activity against methicillin-resistant Staphylococcus aureus (MIC ~ 250 µg/ml). EGF mainly consisted of aromadendrene (31.17%), whereas ECL had citronellal (90.07%) and citronellol (4.32%) as the major compounds. 1,8-cineole was most abundant in EGL (86.51%) and ERL (82.66%).–DISCUSSION AND CONCLUSION: The activity of the oils can be ranked as EGF > ECL > ERL ~ EGL. However, all the oils and the components were hardly active against MDR Gram-negative bacteria. Aromadendrene was found to be the most active, followed by citronellol, citronellal and 1,8-cineole.–PMID: 21591991 [PubMed – indexed for MEDLINE]

    #2624
    AvatarEK
    Keymaster

    [U1]The Bamboozling and BS of the Populace—We were taken off things that were and are healthy to something un balanced and unnecessary to further shorten the life span of a human being
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    Show of the Week February 20 2012
     
    Scientists Sound Alarm Over Threat of Untreatable Gonorrhea in United States
     
    Hidden Agent Orange Chemical
     
    The Power of Estrogen– Male Snakes Attract Other Males
    Walmart Selling GMO or GE Foods
    Bye, bye, privacy. Canada introduces online-spying bill
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    Scientists Sound Alarm Over Threat of Untreatable Gonorrhea in United States
    ScienceDaily (Feb. 9, 2012) — Researchers are continuing to sound the alarm on the growing threat of multi-drug resistant gonorrhea in the United States, according to a perspective in the Feb. 9 issue of the New England Journal of Medicine.—In July of 2011, the U.S. Centers for Disease Control and Prevention released “Cephalosporin Susceptibility Among Neisseria gonorrhoeae Isolates — United States, 2000-2010,” which signaled the potential for resistance to the cephalosporins, the last line of defense for treating gonorrhea.—-The New England Journal of Medicine piece, “The Emerging Threat of Untreatable Gonococcal Infection,” byGail A. Bolan, director of the Division of STD Prevention at the Centers for Disease Control and Prevention in Atlanta, P. Frederick Sparling, professor emeritus at the University of North Carolina, Chapel Hill, and Judith N. Wasserheit, professor and vice chair of the Department of Global Health at the University of Washington in Seattle, issues an urgent call to action to halt the continued increases in drug-resistant gonorrhea.—“It is time to sound the alarm,” said co-author Wasserheit. “Though there is no evidence yet of treatment failures in the United States, trends in decreased susceptibility coupled with a history of emerging resistance and reported treatment failures in other countries point to a likelihood of failures on the horizon and a need for urgent action.”[U1]—According to the article, gonorrhea is the second most commonly reported communicable disease in the United States, with an estimated incidence of more than 600,000 cases annually. It disproportionately affects some populations such as minorities who are marginalized because of race, ethnic group or sexual orientation.—Scientists note that Neisseria gonorrhoeae has always readily developed resistance to antimicrobial agents: it became resistant to sulfanilamide in the 1940s, penicillins and tetracyclines in the 1980s, and fluoroquinolones by 2007. The treatment options recommended by the CDC are now limited to third-generation cephalosporins.–[U2]–But the effectiveness ofcephalosporins for treating gonorrhea has been decreasing rapidly. Through CDC’s Gonococcal Isolate Surveillance Project , researchers are seeing a 17-fold increase in elevated minimum inhibitory concentrations (MICs) — a measure of drug susceptibility. MICs for oral cefixime went from 0.1 percent in 2006 to 1.7 percent in the first six months of 2011.—In the past, when the prevalence of antimicrobial resistance in the Gonococcal Isolate Surveillance Project exceeded 5 percent, national treatment recommendations were changed to focus on other effective drugs. But currently, there are no other drugs.—-The most prominent increases in drug susceptibility to gonorrhea continue to be among men who have sex with men, and in the West, according to the authors.[U3] They wrote that these geographic and demographic patterns are worrisome because they mirror those observed during the emergence of fluoroquinolone-resistant N. gonorrhoeae.—Scientists are calling on a collective effort from physicians, drug companies, and health care providers to help stop the emergence and spread of resistant gonorrhea.–“Investing in rebuilding our defenses against gonococcal infections now, with involvement of the health care, public health, and research communities, is paramount if we are to control the spread and reduce the consequences of cephalosporin-resistant strains,” the scientists wrote.–Story Source-The above story is reprinted from materials provided by University of Washington.
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    Hidden Agent Orange Chemical
     
    Dow AgroSciences (a subsidiary of Dow Chemicals) has developed a new generation of genetically modified (GM) crops — soybeans, corn and cotton — that are engineered to resist an herbicide called 2,4-Dichlorophenoxyacetic acid (2,4-D), which was a major ingredient in Agent Orange
    Once the 2,4-D resistant seeds are released, it will mean farmers will be spraying massive amounts of the herbicide onto U.S. farmland; health effects linked to 2,4-D include birth defects, blood, liver and kidney toxicity
    The 2,4-D-resistant crops are being touted as a solution to Monsanto’s Roundup Ready crops, which have triggered the creation of super weeds; however, the new crops will likely only add to the problem of herbicide resistance, while even greater amounts of herbicides are sprayed onto U.S. farmland, exposing millions to their harmful effects.
    You have until February 27, 2012 to comment on Dow’s application for “non-regulated status” of its 2,4-D-resistant corn. This is a rare opportunity to let your opinion be heard that you do not support products that will increase the use of this toxic chemical once used in Agent Orange.
     
    Agent Orange, produced by both Monsanto and Dow Chemicals, was used to defoliate jungles during the Vietnam War.– During that time, millions of gallons of the toxic chemical mixture were sprayed on trees and vegetation, and the aftermath left hundreds of thousands of Vietnamese sick, with countless numbers of their children suffering birth defects, and a still growing group of U.S. veterans with related diseases ranging from cancer to Parkinson’s disease.—- Agent Orange is no longer produced – Butttttttt!!!! Because Dow AgroSciences (a subsidiary of Dow Chemicals), who was one of the original manufacturers of Agent Orange (AO), has developed a new generation of genetically modified (GM) crops — soybeans, corn and cotton — that are designed to resist a major ingredient in AO: the herbicide called 2,4-Dichlorophenoxyacetic acid (2,4-D).[U4]— The use of 2,4-D, however, is not new, as it is actually one of the most widely used herbicides in the world.— What is new – and disturbingly so – is that now that staple crops like soy and corn have been engineered to be resistant to 2,4-D, it may soon be applied to U.S. arable land on an unprecedented scale The whole point of engineering resistance to an herbicide within a GMO plant, of course, is so that you can “carpet bomb” an entire field, leaving only your “Frankenfoods” standing, without having to exert even a fraction of the effort required raise crops organically and sustainably.— In fact, if 2,4-D resistant crops receive approval and eventually come to replace Monsanto’s failing Roundup-resistant crops as Dow intends, it is likely that billions of pounds will be needed, on top of the already insane levels of Roundup now being used (1.6 billion lbs were used in 2007 in the US alone!).—Agent Orange Ingredient to be Used in GMO Crops— Dow’s new GM product, dubbed “Enlist,” is a three-gene, herbicide-tolerant soybean that has been engineered to be resistant to glyphosate, the active ingredient in Monsanto’s popular Roundup herbicide, along with glufosinate and 2,4-D.[U5] The company expects to earn $1.5 billion in additional profit in 2013 by selling these triple herbicide-resistant seeds. As noted by the U.S. Department of Veteran Affairs:- “The two active ingredients in the Agent Orange herbicide combination were equal amounts of 2,4-dichlorophenoxyacetic acid (2,4-D) and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), which contained traces of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).”— Ironically, while Dow’s new crops would seriously escalate the use of 2,4-D, Monsanto is currently facing a class-action lawsuit involving the other Agent Orange ingredient, 2,4,5-T. The suit alleges that homes and schools near one of its 2,4,5-T chemical plants are now contaminated with cancer-causing dioxin, a byproduct of the manufacturing process. This should be a wake-up call to those considering widespread application of any toxic Agent Orange ingredient.– Dow, however, is touting the new product as a solution to Monsanto’s Roundup Ready GM crops, which currently dominate the GM seed market but are now being overshadowed by problems with weed resistance (not to mention that glyphosate itself is also incredibly toxic, and has been linked to infertility, among other serious health problems).— Where Monsanto has failed, Dow and other chemical rivals like DuPont, Syngenta, and Bayer (which are also working on their own herbicide-resistant GM seeds) see opportunity.[U6] So Dow has trotted in on their white horse to offer a new variety of GM crop, which they say will not pose the “superweed” problem that Roundup Ready crops have created.- This is not so, according to an article in the Proceedings of the National Academy of Sciences, in which researchers state that suggesting 2,4-D will not lead to widespread weed resistance “misrepresented the potential for 2,4-dichlorophenoxyacetic acid (2,4-D)–resistant weeds in 2,4-D–resistant cropping systems and exaggerated the sustainability of their approach to addressing glyphosate-resistant weed problems in agriculture.” They, in fact, note 28 species across 16 plant families that have already evolved resistance to similar herbicides to 2,4-D. Further, as stated on GreenMedInfo, the new Enlist crops are setting the stage for even greater and simultaneous herbicide use, the health ramifications of which are completely unknown- “Instead of learning from Monsanto’s colossal mistakes (which happens when you play geneticist-as-God and use a broad spectrum poison to kill all but your “chosen” plants) Dow AgroScience’s solution is to multiply the problem by a factor of three, creating the “first-ever, three-gene,” herbicide-tolerant staple crops.— What this means is that instead of using only one highly toxic herbicide (Roundup), three will be used simultaneously, further increasing the risk of serious exposures, and setting up the conditions for synergistic toxicities – something that toxicological risk assessments on singular herbicide ingredients, which establish “an acceptable level of harm,” never account for.”-Studies Show Increases in Cancer, Birth Defects With Use of 2,4-D– What is known about 2,4-D so far is not reassuring, considering the devastation caused by Agent Orange. According to the U.S. Environmental Protection Agency (EPA) regarding 2,4-D specifically:
     
    “Health effects of chronic or acute 2,4-D exposure reported for adults included blood, liver, and kidney toxicity. Specific effects included a reduction in hemoglobin and red blood cell numbers, decreased liver enzyme activity, and increased kidney weight. Acute exposure can result in skin and eye irritation. Acute exposure to very high concentrations of 2,4-D can cause the following clinical symptoms: stupor, coma, coughing, burning sensations in lungs, loss of muscular coordination, nausea, vomiting, or dizziness.—Experimental animal studies of chronic oral exposure have reported adverse effects on the eye, thyroid, kidney, adrenals, and ovaries/testes. In addition, some experimental animal studies have reported teratogenic effects (birth defects) at high doses, including increased fetal death, urinary tract malformation, and extra ribs.–When adult female experimental animals were exposed to 2,4-D during their pregnancy and lactation periods, their exposed offspring exhibited neurological effects, including delayed neurobehavioral development and changes in several neurotransmitter levels or binding activities and ganglioside levels in the brain. Delayed neurobehavioral development was manifested as delays in acquisition of certain motor skills such as the righting reflex “The concern is that, just like Monsanto’s genetically engineered corn that is resistant to RoundUp™ (glyphosate) herbicide, the approval of a cultivar resistant to 2,4-D will cause an exponential increase in the use of this toxic agrichemical,” says Mark A. Kastel, senior farm policy analyst with The Cornucopia Institute.– And again, as the EPA acknowledges, this is far from a benign chemical. The Cornucopia Institute continues- “2,4-D is a chlorophenoxy herbicide, and scientists around the world have reported increased cancer risks in association with its use, especially for soft tissue sarcoma and malignant lymphoma. Four separate studies in the United States reported an association with chlorophenoxy herbicide use and non-Hodgkin lymphoma. … Research by the EPA found that babies born in counties with high rates of 2,4-D application to farm fields were significantly more likely to be born with birth defects of the respiratory and circulatory systems, as well as defects of the musculoskeletal system like clubfoot, fused digits and extra digits. These birth defects were 60% to 90% more likely in counties with higher 2,4-D application rates. The results also showed a higher likelihood of birth defects in babies conceived in the spring, when herbicide application rates peak.” In the same way that Dow is now certain that its new three-gene, herbicide-tolerant soybean will not spur the creation of more herbicide-resistant “super weeds,” Monsanto was also historically adamant that Roundup Ready crops would not cause weed resistance either.– Of course, now that the die has been cast, the United States is reaping the consequences with 13 resistant weed species covering more than 11 million acres, mostly those planted with Monsanto’s GM soy, corn and cotton crops. Around the world, 21 weed species are now resistant to glyphosate, up from zero in 1996.- The weeds are making Monsanto’s promises that their GM crops would reduce pesticide use completely laughable — since farmers are being forced to use multiple, and more, pesticides to keep weeds in their GM crops under control — and are turning out to be a very big thorn in Monsanto’s proverbial side.- Monsanto’s solution is similar to Dow’s … add more herbicide-resistant genes to the plants so even more potent herbicide cocktails can be poured over U.S. farmland! According to Monsanto Chief Executive Officer Hugh Grant, who was interviewed in Business Week, the company plans to add resistance to Dicamba, another weedkiller, to Roundup Ready crops by 2015, noting that-“The cavalry is coming.”— The cavalry is coming indeed … unfortunately they are working for the wrong side, with their “war on weeds” causing massive collateral damage to environmental and human health alike. William G. Johnson, a weed scientist at Purdue University, told Business Week, these new technologies may control Roundup-resistant weeds and leave us in “wedded bliss for 10 or 15 years” but “they do select for their own failure:” Adding further insult to injury, Johnson explains that “Dicamba and 2,4-D both tend to volatilize, turning the chemicals into vapor that can drift onto neighboring land … ” accidentally killing nearby crops and exposing greater expanses to its toxic effects.— Let us also not forget that all the “weeds” these herbicides were designed to kill represent biodiversity, without which we would be left with only a handful of staple crops — upon which our entire subsistence now precariously depends. Only because we do not find obvious value in a plant, does not mean it is not there.
     
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    The Power of Estrogen– Male Snakes Attract Other Males
    ScienceDaily (Feb. 10, 2012) — A new study has shown that boosting the estrogen levels of male garter snakes causes them to secrete the same pheromones that females use to attract suitors, and turned the males into just about the sexiest snake in the neighborhood — attracting dozens of other males eager to mate.–This experiment in the famed garter snake caverns of Manitoba, Canada, was one of the first in a field setting to ever quantify the effects of estrogen as a stimulant of pheromones, scientists said, in research just published in the Journal of Experimental Biology. This estrogen, they said, is the same exact chemical found in many animal species, ranging from snakes to amphibians, fish, mammals and humans. The research confirms once again the unusually powerful role that estrogen can play in biology, and is also relevant to widespread concern about the environmental impact of compounds that mimic the effect of estrogen, found in some chemicals and pesticides.—In this study, male snakes were implanted with a small capsule that raised their estrogen level to about that of female snakes. After one year of this estrogen supplementation, the male snakes exuded a pheromone that caused other males to swarm to them and form the writhing “mating balls” that this species of garter snake is known for.—And just as the pheromone production could be stimulated, it could be taken away, the scientists found. When the supplementation was removed for a year, the males reverted to normal function and behavior.– “The amount of estrogen the male snakes received was nothing unusual, just about what a normal female would produce.—“And this was not just some laboratory test,” he said. “These snakes were trying to mate in a natural outdoor environment, in which the males were absolutely sure they had identified a female snake.”—The red-sided garter snake studied in this research depends totally upon pheromones for males to be attracted to and identify female snakes, by actually licking the female with a quick flick of their tongue. But the chemical cues are so extraordinary that in an instant, from one lick, the male can determine the species, sex, population, season, reproductive condition, size and age of its possible partner.–Pheromones are chemical cues that can provide a range of information, and often play a critical role in sexual attraction and reproduction. Snakes are a good model for studying them, Mason said, because they are totally dependent upon them for reproduction.—In garter snakes, the experiments showed just how powerful the mechanism is. Large and older females, preferred by male snakes because they can produce more babies, also have a slightly different chemical signature in their pheromone. Young, small, females can still attract suitors, but not as readily.When male snakes had their estrogen levels elevated, their pheromone production was so strong that other male snakes actually preferred them to small female snakes.–Snakes use a “vomeronasal” organ in the upper palate of their mouth that plays a key role in this sensing process. Other animals, such as dogs, also have keen vomeronasal sensing abilities. Humans still have this organ, but it’s unclear what role, if any, it plays in human sensory ability, Mason said.-The area where this research was done is a natural wonder, many scientists say, attracting hordes of tourists. Each spring, tens of thousands of snakes emerge from limestone caves north of Manitoba, Canada, in an intense competition to mate. Female snakes are swarmed as they emerge from the caves by multiple males that form large, twisting balls, attempting to be the first to mate with the female.—-After that, a different pheromone is emitted which confirms the mating has been accomplished, and the other males lose interest and leave.–This work was supported by the National Science Foundation and the U.S. Environmental Protection Agency.—–Story Source The above story is reprinted from materials provided by Oregon State University. Journal Reference–M. R. Parker, R. T. Mason. How to make a sexy snake: estrogen activation of female sex pheromone in male red-sided garter snakes. Journal of Experimental Biology, 2012; 215 (5): 723 DOI: 10.1242/jeb.064923
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    Walmart Selling GMO or GE Foods
    Do you or anyone you know buy food at Wal-Mart? If you do, you could soon be eating Monsanto GMO corn — unmarked, unlabeled, and untested on humans — with toxins built right into the plant’s DNA.–Monsanto has released their first direct-to-consumer product, a genetically-modified (GM) sweet corn containing Bt toxin, designed to protect the plant by rupturing the stomach of any insect that feeds on it. Monsanto claims the toxin will break down before the corn makes it to your dinner table, but rats fed with the GM corn showed organ failure, and the toxin has been detected in the bodies of pregnant women.–Want to avoid this toxic product? Too bad – it will arrive on shelves unlabeled and untested on humans, starting with this years’ corn crop.Consumers are fighting back. Thanks to consumer pressure, Whole Foods, Trader Joe’s and General Mills have all agreed to not use Monsanto’s GM sweet corn in any of their products. But Wal-Mart, the nation’s largest organic retailer, is holding out.
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    Bye, bye, privacy. Canada introduces online-spying bill
    Move over, SOPA and say your prayers, PIPA. There’s a new bill in the works that, if passed, will pull the plug on how the Internet is used in Canada. —Lawmakers in the Great White North are debating a bill that will pulverize what’s left of online privacy for Canucks. —The Investigative Powers for the 21st Century Act (Bill C-51) is legislation that isn’t new to Canadian Parliament, but after a series of additions and other changes, lawmakers there are expected to begin discussion on it this week. If passed, law enforcement there will be able to monitor all Internet and telephone activity from anyone, anywhere in the country, without having to obtain a warrant.—According to the Calgary Herald out of the province of Alberta, a Conservative-majority government is likely to pass the bill.—Vic Toews, Canada’s minister of public safety, thinks the bill is necessary for the welfare of the nation. “We are proposing to bring to measure, to bring laws into the twenty-first century and provide police with the lawful tools that they need,” he pleads. -Opponents of Toews, however, say that the bill will do far more harm than good. –“I know the criminal justice system is constantly looking for information about criminals, child pornographers etc, but at the same time it seems like an invasion of everyone’s personal information,” University student Jared Exner tells CTV. He’s used the Internet his whole life and is aware of legislation already in place to thwart such things as child pornography. If Bill C-51 is passed, however, anyone operating on the Web or on a mobile device in Canada will be subject to instantaneous, no-questions-asked surveillance. –Towes insists that it’s an issue that’s either black or white. Canadians, says the minister, “can either stand with us or with the child pornographers.”–In an earlier form, the bill died in Parliament along with a provision that allowed “warrantless access” for authorities. A campaign managed to help kill that addendum, but it is back once again. If passed, authorities will be able to view anything, anytime, and some fear that it was install Big Brother over all too broad of a medium.–“It could include anything from email addresses to IP addresses and cellphone-identified numbers,” University of Ottawa law professor Michael Geist tells the Winnipeg Free Press. “The ability to use that kind of information in a highly sensitive way without any real oversight is very real.”—By forcing Internet and cell providers to handle IP addresses, profiles can be constructed of any Canuck that details practically every move they make online. Geist thinks of that as way too encompassing of a regulation and questions why it is even needed.—“One thing (the government) has never provided is the evidence to show how the current set of laws has stymied investigations or created a significant barrier to ensure that we’re safe in Canada,” he adds.–Others fear that if Canadian officials have the power to monitor in real-time without warrants, the all-watching eye will seemingly cease civil liberties.–“How can we trust them not to use private information to intimidate law abiding Canadians to protest a pipeline, or protest pension cut?” asks Francis Scarpaleggia, a Liberal MP for Lac-Saint-Loius. Like Exner, Scarpaleggia is opposed to the bill. New Democratic Party member and digital critic Charlie Angus also is against it, and warns Parliament that, if passed, it will turn each Canadian’s cell-phone into “an electronic prisoner’s bracelet.”—“I say to Vic Toews, ‘Stop hiding behind the boogey man. Stop using the boogey man to attack the basic rights of Canadian citizens,’” adds Angus. “Is Vic Toews saying that every privacy commissioner in this country who has raised concerns about this government’s attempt to erase the basic obligation to get a judicial warrant, is he saying that they’re for child pornography?”—Nearly 100,000 Canadians have so far signed a “stop online spying” petition started by openmedia.ca, a net neutrality lobby group.
     
    TOP F
    [U1]A GOOD ELECTRICAL DISCHARGE WOULD KILL THIS OFF —THIS IS A SCARE MONGERING ARTICL ON AN std THAT HAVE BEEN GENETICALLY ALTERED TO BECOME A BETTER KILLING MACHINE WHILE ENGAGING IN A NORMAL ACTIVITY
    [U2]Genetic engineering Tampering–
    [U3]I find this amusing that this just so happens to Target Men –and in a particular sexual activity—tt would appear this is a designer type infection targeting a specific activity with a specific gender—in ths case Men
    [U4]AO= Agent Orange
    [U5]Does this Sound Like Bio WarFare?? –look at what is going on one is polluting and poisoning and now a Second pollutant that offsets some of the first wave of pollutants abut requires more to further damage an already broken eco system
    [U6]This is absurdity where Monsanto failed—they have had a resounding success in not only introducing this form of debilitation to the human race but while everyone was focused on Monsanto the other companies have been working in collusion to come up with even more ways to debilitate those of us who are not
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    TOP G
    HOME
     
    Show of the Week February 24 2012
     
    Monsanto guilty of chemical poisoning in France
     
    Free speech become too expensive!
    Systematic review- the diagnosis and staging of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis
     
    EFSA sets recommended EU protein intakes at 0.8g/kg per day
    Home Made Protein Shakes
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    Monsanto guilty of chemical poisoning in France
    Mon, Feb 13 2012–By Marion Douet
    PARIS (Reuters) – A French court on Monday declared U.S. biotech giant Monsanto(MON.N: Quote, Profile, Research) guilty of chemical poisoning of a French farmer, a judgment that could lend weight to other health claims against pesticides.–In the first such case heard in court in France, grain grower Paul Francois says he suffered neurological problems including memory loss, headaches and stammering after inhaling Monsanto’s (MON.N: Quote, Profile, Research) Lasso weedkiller in 2004.—He blames the agri-business giant for not providing adequate warnings on the product label.–The ruling was given by a court in Lyon, southeast France, which ordered an expert opinion of Francois’s losses to establish the sum of damages.–Lawyers for Monsanto could not immediately be reached for comment.–Previous health claims from farmers have foundered because of the difficulty of establishing clear links between illnesses and exposure to pesticides.–“I am alive today, but part of the farming population is going to be sacrificed and is going to die because of this,” Francois, 47, told Reuters.–He and other farmers suffering from illness set up an association last year to make a case that their health problems should be linked to their use of crop protection products.—The agricultural branch of the French social security system says that since 1996, it has gathered farmers’ reports of sickness potentially related to pesticides, with about 200 alerts a year.—But only about 47 cases have been recognised as due to pesticides in the past 10 years. Francois, who suffers from neurological problems, obtained work invalidity status only after a court appeal.
    LESS INTENSIVE NOW—The Francois case goes back to a period of intensive use of crop-protection chemicals in the European Union. The EU and its member countries have since banned a large number of substances considered dangerous.–Monsanto’s Lasso was banned in France in 2007 following an EU directive after the product had already been withdrawn in some other countries.-France, the EU’s largest agricultural producer, is now targetting a 50 percent reduction in pesticide use between 2008 and 2018, with initial results showing a 4 percent cut in farm and non-farm use in 2008-2010.—The Francois claim may be easier to argue than others because he can pinpoint a specific incident – inhaling the Lasso when cleaning the tank of his crop sprayer – whereas fellow farmers are trying to show accumulated effects from various products.”It’s like lying on a bed of thorns and trying to say which one cut you,” said a farmer, who has recovered from prostate cancer and asked not to be named.–The French association of crop protection companies, UIPP, says pesticides are all subject to testing and that any evidence of a cancer risk in humans leads to withdrawal of products from the market.[U1]–“I think if we had a major health problem with pesticides, we would have already known about it,” Jean-Charles Bocquet, UIPP’s managing director, said.–The social security’s farming branch this year is due to add Parkinson’s disease to its list of conditions related to pesticide use after already recognising some cases of blood cancers and bladder and respiratory problems.–France’s health and environment safety agency (ANSES), meanwhile, is conducting a study on farmers’ health, with results expected next year.(Writing by Gus Trompiz; Editing by Muriel Boselli, Sybille de La Hamaide and Jane Baird)
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    Free speech become too expensive!
    http://alexandramorton.typepad.com /
    Tomorrow, a judge in a BC court will be asked to make an instantaneous decision on day 20 of a 20-day trial whether to grant an injunction against Don Staniford speaking about the fish farm industry.– Similarly, the proceedings in courtroom #52, Vancouver Law Courts would have little significance if you could not see the roles of Norway, China, Premier Christy Clark and shareholders. The defamation hearing Staniford vs. Mainstream is a test – can the corporate world tolerate democracy. –Big tobacco and Norwegian salmon feedlots hired the same strategist – Hill and Knowlton. The Tobacco Industry knew their product was suspect in killing people, and so it took skilled professionals to get people to keep buying cigarettes. Hill and Knowlton are top-flight, known for managing public relations for the Gulf War, the Exxon oil spill in Alaska, the Three Mile Island nuclear disaster and the massacre at Tiananmen Square. The salmon farmers have spent millions advertising just in the last two years.
    But truth is more powerful.—Staniford used cigarette pack imagery (http://salmonfarmingkills.com) to make the point that farm salmon contain cancer-causing chemicals, that they are spreading like a cancer, choking off wild salmon migration routes and otherwise harming oceans worldwide. Staniford never named Mainstream in these graphics, but BC salmon farming is 92% Norwegian owned and Norway is the biggest shareholder in Mainstream’s parent company, Cermaq. So through Mainstream, Norway is attempting to protect its industry, calling for an immediate gag order on Staniford and $1 million in damages. —Why such a big response to a guy with big mouth and no money?–Under the watchful eye of Justice Adair, we saw evidence that the salmon farming industry knew cancer-causing chemicals are in their product, even as they targeted pregnant women to eat more farm salmon—In 2011, a multi-million dollar ad campaign put fish farm propaganda in our mailboxes saying-“Farmed salmon is natural, nutritious and free of contaminants[U2]”–They know there are contaminants in farm salmon, but they paid huge bucks to tell British Columbians there are none.–While the salmon farming industry has the resources to hire Hill and Knowlton, Staniford’s tools are biting satire, superheroes, three websites, a Captain Condom suit and edgy, British humor. He knows people won’t read dry exposés on the industry. So he pushed the limits and Norway is pushing back hard. Mr. Wotherspoon, commercial litigation lawyer for Fasken Martineau, with 9 offices around the world, is asking Justice Adair for an immediate gag order on Mr. Staniford to shut him up for the few remaining weeks he is in British Columbia, before he is deported.–Norwegians should be concerned about this. In 2010, the Norwegian Nobel Peace Prize was awarded to Chinese free speech dissident, Lui Xiaobo. When Norwegian actress Liv Ullmann accepted the award on Xiaobo’s behalf she said-“To strangle freedom of speech is to trample on human rights, stifle humanity, and suppress truth.” –China took offence and imposed new rules concerning import of Norwegian farm salmon causing a 68% decline in shipments of Norwegian farm salmon to China. Massive stores of farm salmon rotted in warehouses. –While they are vulnerable to the trade winds they create, society’s rapacious corporate giants can save themselves from the spin of the vortex merely by leaning on another leg in another country. What Norway’s salmon feedlot operators lost in Norway, they gained in BC. BC farm salmon export to China skyrocketed from $249,000 in 2010 to more than $3.8 million in 2011 (Vancouver Sun, Feb 2012). –Now, however, free speech is threatening the profitable BC / China farm salmon connection. Staniford keeps saying salmon farming spreads disease. Indeed the ISA virus, the most lethal virus known to salmon and a form of influenza spread from Norway to Chile in 2007 causing 2 $billion dollars of damage. When my colleagues and I reported European strain ISA virus positive tests here in BC, what did the provincial Minister of Agriculture, Don McRae do? He made a statement that Premier Christy Clark would personally tell China we do not have ISA virus in BC. The Canadian Food Inspection Agency testified at the Cohen Inquiry in December that if ISA virus is in BC, trade in farm salmon could cease. –Recent industry trade paper headlines make it clear the farm salmon market is collapsing, because there is too much uneaten farm salmon on the market driving prices down below cost. Two weeks ago the US lifted a 20-year 24% duty on Norwegian farm salmon. This will allow Norwegian companies to sell more farm salmon to the U.S. and might save the motherships, but it puts their BC companies at greater risk.[U3] Farm salmon companies in BC report firing people and downsizing, they cannot survive without the Chinese market.—And so gale force winds spawned on the other side of the planet, when Norway having awarded one man for free speech, have slammed into a small courtroom in Vancouver where Norway seeks to take free speech away from another man. The structure of the courts and democracy are creaking, rivets popping, paint peeling.—Norway, I want to say to you – ISA virus is in BC, cancer-causing chemicals are in your fish, you do use BC as a dump as your companies never shovel their manure and wild fish are being killed in your pens. —You can silence Staniford, but at what cost? You won’t hide these truths, because they are lying around in evidence everywhere. —Corporations are like addicts, they can’t stop themselves. They are blind to everything, but the next quarter. What does it mean when you hand out the Nobel Peace prize in one part of the world and then work to erode democracy where it has become inconvenient to business? —
     
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    Systematic review- the diagnosis and staging of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis
     
    J K Dowman,*† J W Tomlinson,‡ and P N Newsome*†
    *Centre for Liver Research, 5th floor, Institute of Biomedical Research, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    †The Liver Unit, Queen Elizabeth Hospital Birmingham, Edgbaston, Birmingham B15 2TH, UK
    ‡Centre for Endocrinology, Diabetes and Metabolism, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Dr J. K. Dowman, Centre for Liver Research, 5th floor, Institute of Biomedical Research, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK. E-mail: [email protected]
    This uncommissioned systematic review was subject to full peer-review.
    Re-use of this article is permitted in accordance with the Terms and Conditions set out at http://wileyonlinelibrary.com/onlineopen#OnlineOpen_Terms
    Received September 7, 2010; Revised September 27, 2010; Revised December 2, 2010; Accepted December 6, 2010.
    Re-use of this article is permitted in accordance with the Creative Commons Deed, Attribution 2.5, which does not permit commercial exploitation.
    Small right arrow pointing to:This article has been cited by other articles in PMC.
    Other Sections▼
    Abstract
    Background
    Non-alcoholic fatty liver disease (NAFLD) has become the most prevalent cause of liver disease in Western countries. The development of non-alcoholic steatohepatitis (NASH) and fibrosis identifies an at-risk group with increased risk of cardiovascular and liver-related deaths. The identification and management of this at-risk group remains a clinical challenge.
     
    Aim
    To perform a systematic review of the established and emerging strategies for the diagnosis and staging of NAFLD.
     
    Methods
    Relevant research and review articles were identified by searching PubMed, MEDLINE and EMBASE.
    Results—There has been a substantial development of non-invasive risk scores, biomarker panels and radiological modalities to identify at-risk patients with NAFLD without recourse to liver biopsy on a routine basis. These modalities and algorithms have improved significantly in their diagnosis and staging of fibrosis and NASH in patients with NAFLD, and will likely impact on the number of patients undergoing liver biopsy.
    Conclusions
    Staging for NAFLD can now be performed by a combination of radiological and laboratory techniques, greatly reducing the requirement for invasive liver biopsy.
    Other Sections▼
    Introduction
    Non-alcoholic fatty liver disease (NAFLD) encompasses a spectrum of disease ranging from simple steatosis, to inflammatory steatohepatitis (NASH) with increasing levels of fibrosis and ultimately cirrhosis. NAFLD is closely associated with obesity and insulin resistance, and is now recognised to represent the hepatic manifestation of the metabolic syndrome. Since the term NASH was first coined by Ludwig et al. in 1980,1 the prevalence of NAFLD has risen rapidly in parallel with the dramatic rise in population levels of obesity and diabetes,2 resulting in NAFLD now representing the most common cause of liver disease in the Western world.3—Despite recent advances in elucidating the complex metabolic and inflammatory pathways involved in NAFLD, the pathogenesis of steatosis and progression to steatohepatitis and fibrosis/cirrhosis is not yet fully understood.4, 5 While steatosis alone appears to be associated with a relatively benign prognosis,6 factors known to be involved in progression to more advanced and clinically relevant disease include inflammatory cytokines/adipokines, mitochondrial dysfunction and oxidative stress.7 Insulin resistance causes impaired suppression of adipose tissue lipolysis, leading to increased efflux of free fatty acids (FFA) from adipose tissue to the liver.Ø8 Hyperinsulinaemia also promotes hepatic de novo lipogenesis, which is markedly increased in NAFLD patients compared with normal individuals.9 It is now recognised that FFA promote insulin resistance, inflammation and oxidative stress,10, 11 and thus rather than being harmful, hepatic triglyceride accumulation may actually be protective by preventing the harmful effects of FFA.12 The important role of oxidative stress mechanisms, pro-inflammatory cytokines such as TNFalpha and interleukin 6, and adipokines such as leptin (proinflammatory and pro-fibrotic), and adiponectin (anti-inflammatory and insulin-sensitising), in promoting NASH are also becoming increasingly delineated.5 However, evidence that only a minority of patients with NAFLD progress to more advanced stages of NASH suggests that disease progression is likely to depend on a complex interplay between such factors and underlying genetic predisposition.4, 7—The causes, epidemiology and natural history of NAFLD will be covered briefly, before discussing the established and emerging means of assessing and staging patients with NAFLD.
     
    Causes of NAFLD
    In the great majority of cases, NAFLD arises in association with one or more features of the metabolic syndrome, namely insulin resistance, glucose intolerance or diabetes, central obesity, dyslipidaemia and hypertension.13–15 However, after exclusion of a history of significant alcohol intake, which is conventionally <20 g/day,16 other causes of steatosis which should be considered include nutritional causes, e.g. rapid weight loss and total parenteral nutrition, rare metabolic disorders and drug-induced steatosis. Commonly implicated agents include glucocorticoids, amiodarone, synthetic oestrogens and highly active antiretroviral drugs (HAART).16–18 Steatosis is also frequently associated with hepatitis C, particularly genotype 3, and endocrine disorders such as polycystic ovary syndrome (PCOS),19, 20 hypopituitarism21 and hypothyroidism.22
    Epidemiology—The prevalence of NAFLD is estimated to be between 20% and 30% in Western adults,23, 24 rising to 90% in the morbidly obese.25 NASH, the more advanced and clinically important form of NAFLD, is less common, with an estimated prevalence of 2–3% in the general population16 and 37% in the morbidly obese.25 Of concern, NAFLD now affects 3% of the general paediatric population, rising to 53% in obese children,26, 27 with considerable implications for future disease burden. Steatosis was present in 70% of a large unselected cohort of patients with type 2 diabetes.28
    Non-alcoholic fatty liver disease affects all ethnic groups, although prevalence appears to be higher in Hispanic and European Americans compared with African-Americans. This difference remains after controlling for insulin resistance and obesity23, 29 and may be related to ethnic differences in lipid metabolism.23, 30—Natural history
    Patients with a diagnosis of NAFLD have been shown across several studies to have a worse outcome when compared with an age and sex-matched general population.31 Of note, the excess mortality in this group is attributable to both cardiovascular and liver-related causes.32, 33 Since the description in 1999 of the prognostic relevance of different histological types of NAFLD,34 several subsequent studies have demonstrated that the presence of just simple steatosis, with no inflammation or fibrosis, is associated with a similar overall and liver-related mortality to that of an age and gender matched general population. This reinforces the need to stratify patients with NAFLD into simple steatosis or more advanced disease. More advanced disease can be defined as advancing levels of fibrosis and/or the presence/level of inflammation and hepatocyte ballooning. This distinction is pertinent as cohort studies thus far have only identified advanced fibrosis, and not inflammation, as a predictor of worse clinical outcome.32 This may be a type 2 error reflecting small sample sizes, or it may be attributed to additional factors such as PNPLA3 polymorphisms35 regulating the development of fibrosis.
     
    Methods
    A systematic literature search was performed to identify studies assessing methods for the diagnosis and staging of NAFLD/NASH. Relevant articles were identified by searching the PubMed database, MEDLINE and EMBASE, limited to articles published in the English language but not date-restricted. Search terms included fatty liver, NAFLD, NASH, steatosis, AND biomarkers, non-invasive, diagnosis, assessment, staging. Additional searches were also made for each of the individual methods described, e.g. NAFLD fibrosis score, transient elastography, Fibroscan, Fibrotest etc. Selected articles referenced in these publications were also examined.
    Other Sections▼
    Inclusion criteria
    Studies were included if:
    they were meta-analyses, systematic reviews or primary studies of one or more relevant diagnostic/staging tool;
    they included at least 30 subjects, to reduce the risk of including underpowered studies;
    liver biopsy was used as the reference standard;
    the diagnosis of NAFLD had been established with exclusion of other causes of liver disease.
    Exclusion criteria
    Studies were excluded if:
    publications were not in English;
    data on disease stage e.g. fibrosis stage, was not identifiable;
    they were only presented in abstract form.
    Using the search strategy described above, approximately 150 articles were considered. Following review, 68 articles met the selection criteria and were included in the analyses.
    Data extraction
    JD performed the data extraction, which was then checked by the remaining authors (PN and JT).
    Other Sections▼
    NAFLD: making the diagnosis
    The diagnosis of NAFLD should be strongly suspected in the presence of features such as obesity, diabetes and obstructive sleep apnoea (OSA); however, other causes should always be considered before attributing abnormal liver function tests (LFTs) to NAFLD alone (Figure 1). Alternative diagnoses which should be excluded by history and serological testing include the viral hepatitides, excess alcohol consumption, haemochromatosis, autoimmune liver disease, alpha-1 antitrypsin deficiency, Wilson’s disease and drug-induced liver dysfunction.
     
    Figure 1
     
    Figure 1
    Making the diagnosis of NAFLD.
    The majority of patients with NAFLD are asymptomatic and the diagnosis suspected after finding elevated transaminases on routine testing. Hepatic steatosis is also a frequent incidental finding on ultrasound scan (US) performed for other reasons such as suspected gallstone disease. The most common symptoms are right upper quadrant discomfort and fatigue, although the latter may also be caused by OSA which is frequently observed in the typically obese population with NAFLD. Hepatomegaly is the most common clinical finding, with signs of chronic liver disease rarely present in the absence of cirrhosis. A recent study reported the novel finding that increased dorsocervical lipohypertrophy was the anthropometric parameter most strongly associated with severity of steatohepatitis.36
    Although NAFLD is often diagnosed after the finding of mildly abnormal LFTs, more than two thirds of patients have normal aminotransferase levels at any given time37 and the entire histological spectrum of NAFLD can be observed in patients with normal alanine aminotransferase (ALT) values.38, 39 ALT is usually greater than aspartate aminotransferase (AST), and rarely more than three times the upper limit of normal. An AST:ALT ratio greater than 1.0 suggests the presence of more advanced disease.40 Alkaline phosphatase can be slightly elevated but is rarely the only liver function test abnormality.41 Gamma-glutamyltransferase (GGT) is frequently elevated and may also be a marker of increased mortality.42, 43 Low albumin and hyperbilirubinaemia indicate advanced liver disease and are not otherwise features of NAFLD.44 Iron studies may show an elevated ferritin in up to 50% of patients and elevated transferrin saturation in approximately 10%.40 However, such findings do not appear to correlate with elevated hepatic iron concentration, and the role of hepatic iron in the pathogenesis of NASH remains unclear.45–The Fatty Liver Index (FLI) was developed as a simple algorithm to predict fatty liver on USS in the general population.46 The FLI uses four variables of BMI, waist circumference, GGT and serum triglyceride levels, and achieved an accuracy of 0.84 in detecting fatty liver.46 The FLI has since been utilised by several groups in population studies of NAFLD.47–49 Ultrasound (USS) is a commonly used test in patients with suspected NAFLD, with steatosis typically appearing as a hyperechogenic liver. A recent study examined the accuracy of USS in 235 patients with suspected liver disease who underwent liver biopsy, and showed a sensitivity of 64% and specificity of 97%, rising to 91% and 93% respectively in patients with at least 30% steatosis.50 However, the presence of morbid obesity considerably reduces sensitivity and specificity.51 USS is unable to quantify the amount of fat present or provide any staging of disease,52 and is operator-dependent with significant intra- and inter-observer variability.53
    Other Sections▼
    Staging of NAFLD
    Having made a diagnosis of NAFLD, the next step is to determine the severity, as that provides important information on prognosis. Historically this has required liver biopsy, although there have been many recent advances which allow non-invasive management for many patients. When staging patients with NAFLD, there are two aspects to consider; (i) the level of fibrosis and (ii) the level of inflammation/ballooning (Table 1).
    Table 1
    Table 1
    Methods for assessing fibrosis and NASH
    The histological spectrum of NAFLD ranges from simple steatosis through steatohepatitis to fibrosis and cirrhosis. There are no pathological changes which can definitively distinguish NAFLD from alcoholic liver disease (ALD), thus an accurate alcohol history is essential to distinguish between these two common conditions.54 The histological changes in NAFLD are mainly parenchymal and in a perivenular location, although portal and periportal lesions may occur.54 Simple steatosis is usually macrovesicular resulting from accumulation of triglycerides within hepatocytes.44 Features of steatohepatitis include hepatocellular injury, characterised by ballooned hepatocytes, with inflammation and fibrosis.54 Mitochondrial abnormalities may occur in NASH, but rarely in simple steatosis,11 supporting a role for mitochondrial defects in the pathogenesis of NAFLD-related liver injury.54, 55 The typical histological features of steatosis and inflammation often disappear in advanced disease,56, 57 thus many cases of ‘cryptogenic’ cirrhosis are likely caused by NASH.56–58 Hepatocellular carcinoma is a well-recognised complication of NASH-related cirrhosis,59, 60 but can also be associated with precirrhotic NAFLD.61, 62 Several systems have been proposed for the histological assessment of NAFLD, of which the Kleiner NAFLD activity score (NAS)63 is probably the most well established. The NAS provides a composite score based on the degree of steatosis (0–3), lobular inflammation (0–3) and hepatocyte ballooning (0–2), with an additional score for fibrosis. A score of ≥5 suggests probable or definite NASH, and <3 indicates that NASH is unlikely.63 However, although liver biopsy currently remains the gold standard for diagnosis of NASH, limitations of this technique include intra-observer variation63, 64 and sampling variability,65, 66 with features such as fibrosis often not uniformly distributed.54[U4]
    Non-invasive assessments of NAFLD severity—Such assessments can provide information on the amount of liver fibrosis and/or the presence of NASH, features which are usually, but not always, found together. The focus on fibrosis is based on cohort studies which demonstrate that fibrosis, rather than inflammation, predicts outcome. Several non-invasive diagnostic panels and scoring systems have been developed with varying diagnostic utility. The uneven distribution of fibrosis throughout the liver in NAFLD indicates that such scoring systems may potentially represent a more accurate reflection of global liver fibrosis severity than is permitted by the current gold standard liver biopsy,67[U5] which samples only 1/50 000th of the organ and is prone to significant sampling error.65, 66
    Assessment of fibrosis
    (i) Demographic factors and simple blood tests: Several diagnostic panels have been developed to facilitate the non-invasive assessment of NAFLD and differentiation between different stages of disease. These are generally based on a number of laboratory measurements, often in combination with clinical parameters such as age, sex and BMI. Such scoring systems have generally demonstrated greater utility in the detection of advanced fibrosis than intermediate and early stages of fibrosis, a group potentially more likely to benefit from therapeutic interventions.37–The BARD score is a simple scoring system designed to identify NAFLD patients with a low risk of advanced disease. It combines three variables of BMI, AST/ALT ratio (AAR) and the presence of diabetes into a weighted sum (BMI ≥28 = 1 point, AAR of ≥0.8 = 2 points, DM = 1 point), to generate a score from 0 to 4. In the original study, a score of 2–4 was shown to be associated with an odds ratio for advanced fibrosis of 17 and a negative predictive value of 96%.68 A further study of the BARD score in 138 patients with biopsy-proven NAFLD revealed an area under the receiver operating curve (AUROC) of 0.67 (95% CI, 0.56–0.77), with sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of 51%, 77%, 45% and 81% respectively.69 In a recent study including 145 patients with biopsy-proven NAFLD, McPherson et al. compared the diagnostic performance of five simple non-invasive tests [BARD score, NAFLD fibrosis score, FIB-4 score, AST to platelet ratio index (APRI) and ALT/AST ratio], for the identification of NASH-related advanced fibrosis. Here the BARD score demonstrated an AUROC of 0.77, with sensitivity 89%, specificity 44%, NPV 95% and PPV 25%.70 The BARD score was also validated in a Polish NAFLD cohort, where an NPV of 97% was demonstrated,71 but appeared less useful in a Japanese cohort, where the AUROC was 0.73 with NPV 77%.72 The BARD score is easily calculated and thus represents a simple tool for excluding the presence of advanced fibrosis in NAFLD patients. The AST-to-platelet ratio index (APRI),73 AST/ALT ratio,74 and FIB-4 score75 have previously demonstrated utility in the non-invasive assessment of fibrosis in a number of chronic liver diseases. Several recent studies have also examined the role of these markers in NAFLD, as will be described.–The APRI was originally developed for use in chronic hepatitis C,73 but its utility in NAFLD has since been studied by a number of groups. Using this score, Cales et al. demonstrated an AUROC of 0.866 for significant fibrosis, 0.861 for severe fibrosis and 0.842 for cirrhosis in a study of 235 NAFLD subjects.76 However, significantly lower values were obtained in other studies, where AUROCs of 0.564 for significant fibrosis, 0.568 for advanced fibrosis,77 and 0.786 for predicting cirrhosis78 were demonstrated. In their study of 145 NAFLD patients, McPherson et al. reported an AUROC of 0.67 for the diagnosis of advanced fibrosis.70
    The AST/ALT ratio (AAR) is calculated using two widely available laboratory liver function tests. In addition to its utility as an individual marker, the AAR is also a component of several other fibrosis scoring systems including the NAFLD Fibrosis score and BARD score. Despite its simplicity, using a cut-off of 0.8 McPherson et al. demonstrated an AUROC of 0.83, with sensitivity 74%, specificity 78% and NPV of 93% for the diagnosis of advanced fibrosis in NAFLD using the AAR.70 The United States Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) recently investigated the utility of readily available clinical and laboratory variables to predict histological severity of NASH in >600 patients with biopsy-proven NAFLD. In this study, a combination of serum AST, ALT and the AAR performed only modestly (AUROC 0.59) for predicting steatosis, but was able to predict cirrhosis with an AUROC of 0.81. However, the addition of demographic data, comorbidities and several other routinely measured laboratory tests increased the AUROCs to 0.79 for NASH and 0.96 for cirrhosis.79–The FIB-4 test combines age with three standard biochemical values (platelets, ALT and AST) to assess fibrosis. In NAFLD FIB-4 has demonstrated similar results to the AST/ALT ratio where, using a cut-off of 1.3, an AUROC of 0.86, sensitivity 85%, specificity 65% and NPV of 95% were demonstrated for the diagnosis of advanced fibrosis.70 In a US-based comparison of several non-invasive markers of fibrosis in 541 NAFLD patients, FIB-4 had the highest AUROC of 0.802, with PPV and NPV of 80% and 90% respectively for diagnosis of advanced fibrosis. In this study, AUROCs for the NAFLD fibrosis score, AAR, APRI, AST:platelet ratio and BARD score were 0.768, 0.742, 0.73, 0.72 and 0.70 respectively.80—Increased serum GGT level has also been shown to be associated with advanced fibrosis in NAFLD, with a study of 50 NAFLD patients demonstrating an AUROC of 0.74 for the prediction of advanced fibrosis. Using a cut-off serum GGT value of 96.5 U/L, GGT predicted advanced fibrosis with 83% sensitivity and 69% specificity.81–FibroMeter is a panel of serum markers which was originally developed for staging fibrosis in chronic HCV.82 However, FibroMeter NAFLD has since been developed which has shown good diagnostic accuracy in staging NASH-related fibrosis. This panel combines seven variables (age, weight, fasting glucose, AST, ALT, ferritin and platelet count), and in a study of 235 NAFLD patients demonstrated AUROCs of 0.943 for significant fibrosis, 0.937 for severe fibrosis and 0.904 for cirrhosis respectively. The sensitivity, specificity, PPV and NPV of FibroMeter for diagnosing significant fibrosis were 78.5%, 95.9%, 87.9 and 92.1%.76
    The NAFLD fibrosis score (NFS) is a panel comprising six variables of age, hyperglycaemia, BMI, platelet count, albumin and AST/ALT ratio, which was constructed using a large panel of 733 biopsy-proven NAFLD patients across several centres worldwide. Two cut-off scores were generated to predict the likelihood of the presence or absence of advanced fibrosis respectively.67 In the original study, by applying the low cut-off score (−1.455), the NFS had an NPV of 93% and 88% in the estimation and validation groups respectively for excluding the presence of advanced fibrosis. By applying the high cut-off score (0.676), PPVs of 90% and 82% in the estimation and validation groups respectively were achieved for predicting the presence of advanced fibrosis. The AUROC was 0.84, and application of this model to the
    ****************************************************************************
    EFSA sets recommended EU protein intakes at 0.8g/kg per day
    The European Food Safety Agency (EFSA) has published population reference intakes
    (PRIs) for protein, the latest stage of its work on dietary reference values (DRVs),
    with a particular focus on levels needed during pregnancy and childhood. A PRI indicates
    the amount of an individual nutrient that the majority of people in a population need for good health
    depending on their age and sex.—The population reference intake for adults of all ages was
    estimated to be 0.83g protein/kg body weight per day [U6]and,” said the Parma-based
    assessor. .In delivering an opinion on EU is applicable both to high quality protein and
    to protein in mixed diets protein intakes, EFSA’s Panel on Dietetic Products, Nutrition and
    Allergies (NDA) also acknowledged that intakes twice the 0.83 level were, regularly
    consumed from mixed diets by some physically active and healthy adults in Europe
    [U7]The NDA said such levels are considered safe “Data from food consumption surveys show
    that actual mean protein intakes of adults in Europe are at, or more often above, the PRI of 0.83g/kg
    body weight per day,” the NDA wrote.—But less positively for industry, the panel said dietary
    reference values (DRVs) could not be established for several health conditions due to insufficient
    data The available data on the effects of an additional dietary protein intake beyond
    the PRI on muscle mass and function, on body weight control and obesity (risk) in
    children and adults, and on insulin sensitivity and glucose homeostasis do not
    provide evidence that can be considered as a criterion for determining DRVs for
    protein,” it said.–likewise, the available evidence does not permit the conclusion
    that an additional protein intake might affect bone mineral density and could be
    used as a criterion for the setting of DRVs for protein.”–In this way it added that DRVs
    could not be set for amino acids because they “are not provided as individual nutrients but in the
    form of protein.”“In addition, the Panel notes that more data are needed to obtain sufficiently precise
    values for indispensable amino acid requirement. ”Demographic breakdown The panel recommended
    PRIs for population groups such as pregnant women who should consume 1, 9 and 28g of
    protein per day in the first, second and third trimesters of pregnancy respectively.
    Lactating women should consume 19g/d for the first six months and 13g/d afterwards.-
    [U8]Children should also increase intake above the PRI depending on their age.-” Patent
    pending Magtein promises to be the next key ingredient for memory and cognitive health. Two
    published studies indicate Magtein’s role in short–term and long–term memory improvement and
    alleviating anxiety response-Data from dietary surveys show that the average protein intakes in
    European countries vary between 67-114g/d in adult men and 59-102g/d in women – between 12-20%
    of total energy intake for both sexes. The NDA said accurate European protein intake data per/kg was scarce
    but varied between 0.8 to 1.25g/kg for adults. EFSA has raised a number of positive points about protein,
    not least the possibility that the PRV should be increased for pregnant and lactating women, claims
    Suzane Leser, nutrition manager, Volac Lifestyle Ingredients. Labelling misalignment? Leser said that
    on reading the Opinion we see a potential misalignment between EFSA recommendations
    and the new Food Information Regulation (FIR”The EFSA opinion states that when the
    aim is to indicate a product’s potential to supply amino acids, the use of the NCF specific
    to the food is more relevant. For dairy products this is x 6.38 as established in Directive 92/46/
    EEC for the sale of milk and milk products. However, to aid the simplicity of the labelling process the new
    Food Information Regulation states that a standard conversion rate should be used for all protein
    sources: x 6.25. This means that protein levels based on N x 6.25 typically underestimate
    the true protein contribution from high quality protein sources and, most critically,
    significantly overestimate the contribution from protein sources of low quality.[U9]”
    She argues it is not just a consumer labelling issue but potentially one of resource efficiency. ”In line
    with the above Directive, dairy products are commonly traded with protein NCF x 6.38. Assuming all
    customers declare protein in compliance with labelling regulations as N x 6.25, there must be
    unnecessary over-supply. This is uneconomical because protein is the most costly of the food elements
    to consumers, and from a sustainability perspective hardly in line with the European Sustainable
    Consumption and Production Policies
    *************************************************************************
    Home Made Protein Shakes—will give some ideas to make a good protein shake ( meal ) take 30 grams ( or one scoop of a container for protein ) of gelaton— and add to 2 cups of water in a pot and boil and when water is boiling add the gelaton—in the blender add 3-4 eggs ( whole eggs with no shells) 1 tsp of oil or a slice of butter—add herbs or condiments of choice to this ( garlic and onion powders—sea salt—tumeric—pepper –paprika) once the gelaton is dissolved then get the blender going with the eggs –leave the lid on top and open center of lid where you can pour into the blender while blending—once the pot is emptied then allow for blending for about 2-4 minutes—when done you will have cooked the egg in that solution and it will have blended—you have now a protein shake with the equivalency of 45 grams of protein—
     
    ØTake ¼ container of cottage cheese add to blender –add water 1 ½ cup – 2cup-add berries or fruit—add 1 tablespoon of oil of your choice—and add gelaton 15 grams—blend for 3 minutes—you have 40 grams of protein
     
    ØTake yogurt ( Balkan Style original) and take half the container and add 1 multiple vitamin complete with B’s and other nutrients add 2 capsules—add fat ( of choice) and add water 2 cups—and add cocoa and 1 scoop of dried egg protein—blend together for 3 minutes—when done you have made a meal replacement with a complete meal 30 grams of protein
     
    ØIn the Morning consume 3 eggs and 2 oz of yogurt and add fat to either the eggs or yogurt—-have some fruit like apples or berries or citrus—have a tea—this will give you 20 grams of protein
     
    So you can see how it is easy to get your daily requirement of protein—
     
    ØDuring the day consume a adequate amount of protein from nut –animal –dairy sources –and always ad fat with the protein
     
     
    TOP G
    [U1]This is what the FDA used to do back in the 50’s til they were corrupted—so Europe still has it’s moral compass
    [U2]ALL BS they have a high level of antiobiotic and genetic engineering so it is not all that safe
    [U3]Only America Would Kill there own populace with poisons no one else would use
    [U4]Pay attention to this—conventional diagnostics will not pick this up
    [U5]Pay attention to this—conventional diagnostics will not pick this up
    [U6]What you do is convert your weight to kilos ( divide by 2.2) and then divide that by .83—say your 150 lb person divide by 2.2 = 68 kilos ( approx) then divide that b 0.83—in this case 150 lb person would require minimally- 82 grams of protein a day based on this—and that would be as well contingent to physical activity
    [U7]This would be accurate since they have a higher out put they would require more
    [U8]Far to low this will not adequately sustain the protein requirements an in fact be deficient
    [U9]This Hides Soy-Pea and hemp and the rice proteins which are way way down in the BV rating and if they set the standard to one universal measurement then they will confuse the consumer into thinking they have a good protein source when in fact what they are eating will shut down protein absorption and shut down independent suppliers of protein
    ******************************************************************************************************************
    TOP H
    HOME
     
    Show of the Week February 27 2012
     
    Fatty liver Resolutions
     
    Food police reject preschooler’s homemade lunch… in favour of chicken nuggets
    Myths and Truths About Fiber
    Butyrate—what it does
     
    Betaine— Recipe for NAFLD

    #2625
    AvatarEK
    Keymaster

    Fatty liver Resolutions
     
    Betaine may help to prevent and reverse Fatty Liver.
     
    Amino Acids
     
    Cysteine may help to prevent Alcohol-induced Fatty Liver:
     
    N-Acetyl-Cysteine (NAC) may help to prevent Alcohol-induced Fatty Liver. references
     
    S-Adenosylmethionine (SAMe) may help to prevent and treat Fatty Liver. references
    Taurine may help to prevent Alcohol-induced Fatty Liver.
     
    Carbohydrates
     
    Chondroitin Sulfate may counteract the ability of high consumption of Dietary Fats to cause Fatty Liver.
     
    Lipids
     
    Gamma-Linolenic Acid (GLA) may help to prevent Alcohol-induced Fatty Liver. references
    Phosphatidylcholine may help to prevent and treat Fatty Liver.
     
    Peptides
     
    Carnitine may alleviate and prevent Fatty Liver – some evidence suggests that Carnitine deficiency within the Liver may be the underlying cause of Fatty Liver.
     
    Polyphenols
     
    Cynarin may inhibit the ability of Alcohol (ethanol) to cause Fatty Liver. references
    Silymarin may alleviate Fatty Liver.
     
    Vitamins
     
    Fatty Liver may occur as a result of Choline deficiency.
    Folic Acid may help to prevent (Alcohol-Related) Fatty Liver.
    Inositol may help to prevent Fatty Liver. references
    The Pantethine form of Vitamin B5 (600 mg per day) may cause the total disappearance of some cases of Fatty Liver.
     
    Vitamin B12 may help to prevent Fatty Liver.
    Vitamin C (when consumed prior to or during Alcohol consumption) may inhibit the ability of Alcohol to cause Fatty Liver.
    Vitamin E (when consumed prior to or during Alcohol consumption) may inhibit the ability of Alcohol to cause Fatty Liver.
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    Recipe for NAFLD—
    Using beets and apple as a sauce—take 2 apples peeled and 1 beet chopped and add to a blender and add ¼ cup of water and blend til it is sauced –stop the blender and add to a glass container and utilized 2-3 oz 3 times a day to increase the betaine levels
     
    Utilizing HCL supplements with pepsin taking them orally with every meal
     
    Taurine Supplements will increase Bile salts that will break down the fatty build up in the liver
     
    Sunflower Lecithin or Egg Yolk Lecithin—will remove the excessive fat build up
     
    Lipase- will break down the fats in the diet will make it easier on the liver and pancreas
     
    Using B5 daily will lower the fatty build up as well
     
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    Food police reject preschooler’s homemade lunch… in favour of chicken nuggets
    By Meghan Keneally–15th February 2012
    A preschool girl was told her homemade meal wasn’t healthy enough – so a school cafeteria monitor made her eat chicken nuggets instead.–The rejected meal consisted of a turkey and cheese sandwich on whole wheat bread, with a side of a banana, potato chips, and apple juice.–“What got me so mad is, number one, don’t tell my kid I’m not packing her lunch box properly” , the mother from North Carolina, who wished to remain anonymous, told a local newspaper.–Homemade goodness: A 4-year-old girl was told that her turkey and cheese sandwich was unhealthy and a school monitor made her buy a lunch–Alternative: The school-made lunch included chicken nuggets instead–‘I pack her lunchbox according to what she eats. It always consists of a fruit. It never consists of a vegetable. She eats vegetables at home because I have to watch her because she doesn’t really care for vegetables.’–The Department of Health and Human Services requires students to eat lunches that consist of meat, milk, grain, and two servings of fruit or vegetables.–It isn’t clear what the entire meal that the cafeteria at West Hoke Elementary School consisted of, but all that the picky four-year-old girl ate were the chicken nuggets.–The mother still wonders what it was exactly that disqualified her meal, and she expects that the bag of potato chips were potentially the problem.–That said, Jani Kozlowski, the spokesperson from the DHHS children’s division said that the meal sounds like it would have passed the federal guidelines test.–‘With a turkey sandwich, that covers your protein, your grain, and if it had cheese on it, that’s the dairy,’ Ms Kozlowski told The Carolina Journal.–‘It sounds like the lunch itself would’ve met all of the standards,’ she said, not having worked with the school in question herself.–On top of the wasted food that was sent home with the little girl at the end of the day was a $1.25 bill for the ‘healthy’ school lunch.-‘I don’t feel that I should pay for a cafeteria lunch when I provide lunch for her from home,’ the mother wrote in a letter to her state representative.
    http://www.dailymail.co.uk/news/article-2101354/Food-police-reject-preschoolers-homemade-lunch–favour-chicken-nuggets.html#ixzz1mgu7JFmU
     
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    Myths and Truths About Fiber
    [1]For decades, fiber has been touted as an essential component of a healthy diet. The supposed benefits of a high-fiber diet have been drilled into us through recommendations by our doctors, government, and the food industry alike, yet many of these health claims have not been proven by research.—In fact, many studies have demonstrated that excess intake of fiber may actually be harmful, particularly for gut health.–The majority of the research supporting the benefits of dietary fiber come from epidemiological studies that link the consumption of fiber-rich fruits and vegetables with a lowered risk of certain diseases such as obesity, heart disease and cancer, particularly colon cancer. (1 [2]) Yet when tested in the lab, controlled intervention trials that simply add fiber supplements to an otherwise consistent diet have not shown these protective effects. (2 [3]) (3 [4]) (4 [5])–The Institute of Medicine recommends a daily fiber intake of 38 grams for men and 25 grams for women (5 [6]), which may come from dietary fibers, both soluble or insoluble, or the addition of “functional fibers” to the diet. The IOM defines functional fibers as non-digestible carbohydrates that have been isolated or extracted from a natural plant or animal source, or they may be manufactured or synthesized. Examples of functional fibers are psyllium husks, chitin from crustacean shells, fructooligosaccharides, polydextrose, and resistant dextrins. (6 [7])—These functional fibers are often added to processed foods as a way to bulk up the fiber content for consumers looking to meet the IOM intake guidelines. A recent report by NPR commented that despite the lack of significant evidence linking fiber intake to health outcomes such as reduced heart disease or cancer, many consumers are buying foods that are fortified with synthetic fiber additives under the guise of health promotion. (7 [8]) Three grams of added fiber is enough to allow these food products to claim to be a good source of fiber, and the food industry has used these fiber guidelines as a way to increase their sales of grain-based products in particular. (8 [9])-Tan and Seow-Choen, in their 2007 editorial on fiber and colorectal disease, call insoluble fiber “the ultimate junk food”, as “it is neither digestible nor absorbable and therefore devoid of nutrition.” (9 [10]) Excess insoluble fiber can bind to minerals such as zinc, magnesium, calcium, and iron, preventing the absorption of these vital nutrients. (10 [11]) Large excesses of certain soluble fibers like pectin and guar may also inhibit pancreatic enzyme activity and protein digestion in the gut, leading to an anti-nutritive effect. (11 [10])– The addition of insoluble and soluble fibers to processed foods may actually cause these foods to be even less nutritious than if they were not enriched with any fiber at all.–A high-fiber diet has also been described as a preventative strategy for the development of diverticulosis, a disease that is markedly more common in Western countries. However, when researchers tested the theory that a high-fiber diet prevented diverticulosis, they not only found that a high intake of fiber did not reduce the prevalence of diverticulosis, but that a high-fiber diet and greater number of bowel movements were independently associated with a higher prevalence of diverticula. (12 [12]) Interestingly, this study found no association between the presence of diverticulosis and red meat intake, fat intake, or physical activity, which are other factors commonly attributed to diverticulosis.–The researchers hypothesized that one possible effect of a high-fiber diet in the development of diverticulosis could be the quantitative and qualitative changes in gut bacteria due to the excessive fiber intake. Both insoluble and soluble fibers are shown to alter gut bacteria in as little as two weeks. (13 [13]) It is possible that the high levels of excess fiber and overgrowth of intestinal bacteria may have contributed to the development of diverticular pouches in the colon.-This hypothesis brings up another side to the fiber debate: the effect of dietary fiber on beneficial gut bacteria, as well as the bacterial fermentation of undigested soluble fiber into short-chain fatty acids such as butyrate. When we eat the soluble fibers found in whole plant foods, the bacteria in our gut ferment these fibers into short-chain fatty acids like butyrate, proprionate, and acetate, and greater amounts of fiber consumed will lead to greater short-chain fatty acid production. (14 [14]) In this case, naturally occurring soluble fibers are very important for feeding the friendly bacteria that live in our guts.[U1]–One of the risks of long term very low-carbohydrate (VLC) diets, in my view, is the potentially harmful effect they can have on beneficial gut flora. VLC diets starve both bad and good gut bacteria, which means these diets can have therapeutic effects on gut infections in the short term, but may actually contribute to insufficiency of beneficial strains of gut bacteria over the long term. Providing adequate levels of carbohydrate and soluble fiber to feed friendly bacteria is important for optimizing digestive health and maintaining the integrity of the gut lining through the production of short-chain fatty acids.–Stephan Guyenet has written an excellent blog post describing the benefits of butyrate and other short-chain fatty acids on the maintenance of healthy gut integrity. (15 [15]) Butyrate has anti-inflammatory effects, increases insulin sensitivity, and may delay the development of neurodegenerative diseases. It may also be helpful in the treatment of diseases of the colon such as Crohn’s, IBS or ulcerative colitis. (16 [16])—Stephan believes that butyrate may play a significant role in healthy metabolic function, stress resistance, and the immune response. He also asserts that the epidemiologically observed benefits of a diet high in naturally occurring fiber are likely due to the higher butyrate production from these diets. In this case, a higher fiber diet could be protective and beneficial for health, particularly if the fiber is soluble.
    So what does this mean for our own consumption of fiber?
    Ideally, dietary fiber should be coming from whole food plant sources. Many foods in the Paleo diet are great sources of both soluble and insoluble fiber, such as yams and sweet potatoes, green leafy vegetables, carrots and other root vegetables, fruits with an edible peel (like apples and pears), berries, seeds, and nuts. Interestingly, butyrate itself is also found in high-fat dairy products such as butter and cheese, and can also be provided by the bacteria found in fermented foods. (17 [17])—-Although I recommend that most people get fiber from whole foods, there are some people that may benefit from soluble fiber supplementation – including those that aren’t able to eat fruit or starch due to blood sugar issues or weight regulation, and those with severely compromised gut flora or gut dysbiosis. In these cases I’ve found soluble fiber and/or prebiotic supplements to be helpful.—For healthy people, including a variety of fibrous whole plant foods, fermented foods, and high-fat dairy as tolerated should eliminate the need to supplement with extra fiber, especially those insoluble fibers that are from sources high in anti-nutrients. A Paleo diet with some level of attention paid to the quality and quantity of vegetables, fruits, and starchy tubers can provide adequate levels of soluble fiber to feed the friendly bacteria in the gut that convert these fibers into beneficial short-chain fats like butyrate.
    Recommended supplements if needed:
    Prebiotic: Klaire Labs Biotagen [18]
    Soluble fiber: Organic Acacia Fiber [19]
    Caution: it’s crucial to start with a very low dose of prebiotic or soluble fiber and build up slowly over time. This will minimize any potential adverse reaction that can occur with significant changes (even positive changes) to the gut microbiome. For Biotagen, start with 1/4 of 1/8 of a tsp (1/32 tsp.) and increase by 1/32 of a tsp every 4-5 days. For Organic Acacia Fiber, start with 1/4 of a tsp. once per day and build slowly from there.
    [1] Image: http://chriskresser.com/wp-content/uploads/all-bran.jpg
     
    [2] 1: http://www.ncbi.nlm.nih.gov/pubmed/19335713
     
    [3] 2: http://www.ncbi.nlm.nih.gov/pubmed/10770980
     
    [4] 3: http://jn.nutrition.org.libproxy.lib.unc.edu/content/133/10/3141.full
     
    [5] 4: http://www.ncbi.nlm.nih.gov/pubmed/12223437
     
    [6] 5: http://www.iom.edu/~/media/Files/Activity%20Files/Nutrition/DRIs/DRI_Macronutrients.pdf
     
    [7] 6: http://lpi.oregonstate.edu/infocenter/phytochemicals/fiber
     
    [8] 7: http://www.npr.org/blogs/thesalt/2012/02/13/146706553/is-adding-fiber-to-food-really-good-for-your-health
     
    [9] 8: http://www.cnpp.usda.gov/Publications/FoodSupply/FiberFactSheet.pdf
     
    [10] 9: http://www.wjgnet.com/1007-9327/13/4161.pdf
     
    [11] 10: http://www.tandfonline.com/doi/abs/10.1080/10408399109527539
     
    [12] 12: http://www.gastrojournal.org/article/S0016-5085(11)01509-5/abstract
     
    [13] 13: http://www.sciencedirect.com/science/article/pii/S0271531705802167
     
    [14] 14: http://chriskresser.comwww.ajcn.org/cgi/reprint/33/4/754.pdf
     
    [15] 15: http://wholehealthsource.blogspot.com/2009/12/butyric-acid-ancient-controller-of.html
     
    [16] 16: http://www.ncbi.nlm.nih.gov/pubmed/16633129
     
    [17] 17: http://huntgatherlove.com/content/human-colon-evolution-part-4-secrets-butyrate
     
    [18] Klaire Labs Biotagen: http://www.amazon.com/gp/product/B001PYXMTQ/ref=as_li_ss_tl?ie=UTF8&tag=chrikres-20&linkCode=as2&camp=1789&creative=390957&creativeASIN=B001PYXMTQ
    [19] Organic Acacia Fiber: http://www.amazon.com/gp/product/B0002ON8DU/ref=as_li_ss_tl?ie=UTF8&tag=chrikres-
    20&linkCode=as2&camp=1789&creative=390957&creativeASIN=B0002ON8DU
     
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    Butyrate—what it does
     
    Sources of Butyrate—
    Butter: 3,230 Parmesan Cheese 1,510
    Swiss Cheese 1,100 Cream 1,080
    Cheddar Cheese 1,050 Gruyere Cheese 1,050
    Edam Cheese 1,000 Gouda Cheese 1,000
    Cream Cheese 1,000 Feta Cheese 775
    Blue Cheese 658 Milk 75
     
    Butyric Acid may Enhance the Function of these Substances
     
    Microorganisms-Butyric Acid functions as a nutrient for the Beneficial Bacteria within the Digestive Tract.
     
    Minerals-Butyric Acid may facilitate the absorption of Calcium in the Colon.
    Butyric Acid may facilitate the absorption of Magnesium in the Colon.
     
    These Substances may Enhance the Function of Butyric Acid
     
    Carbohydrates—Dietary Carbohydrates (especially Polysaccharides) are fermented (by Beneficial Bacteria) within the Large Intestine resulting in the manufacture of Butyric Acid–Inulin may enhance the production of Butyric Acid in the Colon.
    Of all Carbohydrates, Starch produces the greatest concentration of Butyric Acid:
    The constituent of Starch that most contributes to the production of Butyric Acid is Amylose that escapes digestion (i.e. Resistant Starch).
    Fructooligosaccharides (FOS) (by nourishing Beneficial Bacteria in the Intestines which produce Butyric Acid) may facilitate the endogenous production of Butyric Acid in the digestive tract.
    Larch Arabinogalactan may stimulate the body’s production of Butyric Acid.
     
    Lipids—Acetic Acid may enhance the ability of Butyric Acid to stimulate the absorption of Calcium and Magnesium in the Colon.
     
    Microorganisms–Beneficial Bacteria within the Large Intestine (especially the Colon) are responsible for the fermentation of dietary Carbohydrates that result in the production of Butyric Acid.
     
    Pharmaceutical Drugs–Aspirin may enhances the ability of Butyric Acid to prevent Colon Cancer.
     
    Resveratrol may enhance the ability of Butyric Acid to prevent Colon Cancer.
     
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    Betaine
     
    Betaine may help to prevent and reverse Fatty Liver. references
     
    Amino Acids
     
    Cysteine may help to prevent Alcohol-induced Fatty Liver: references
     
    N-Acetyl-Cysteine (NAC) may help to prevent Alcohol-induced Fatty Liver. references
     
    S-Adenosylmethionine (SAMe) may help to prevent and treat Fatty Liver. references
    Taurine may help to prevent Alcohol-induced Fatty Liver. references
     
    Carbohydrates
     
    Chondroitin Sulfate may counteract the ability of high consumption of Dietary Fats to cause Fatty Liver. references
     
    Lipids
     
    Gamma-Linolenic Acid (GLA) may help to prevent Alcohol-induced Fatty Liver. references
    Phosphatidylcholine may help to prevent and treat Fatty Liver. references
     
    Peptides
     
    Carnitine may alleviate and prevent Fatty Liver – some evidence suggests that Carnitine deficiency within the Liver may be the underlying cause of Fatty Liver. references
     
    Polyphenols
     
    Cynarin may inhibit the ability of Alcohol (ethanol) to cause Fatty Liver. references
    Silymarin may alleviate Fatty Liver. references
     
    Vitamins
     
    Fatty Liver may occur as a result of Choline deficiency. references
    Folic Acid may help to prevent (Alcohol-Related) Fatty Liver. references
    Inositol may help to prevent Fatty Liver. references
    The Pantethine form of Vitamin B5 (600 mg per day) may cause the total disappearance of some cases of Fatty Liver.
     
    Vitamin B12 may help to prevent Fatty Liver. references
    Vitamin C (when consumed prior to or during Alcohol consumption) may inhibit the ability of Alcohol to cause Fatty Liver.
    Vitamin E (when consumed prior to or during Alcohol consumption) may inhibit the ability of Alcohol to cause Fatty Liver.
     
    Betaine-2
     
    Betaine (especially the Trimethylglycine (TMG) form of Betaine) may help to prevent Cardiovascular Diseases (due to Betaine functioning as a methyl donor which lowers Homocysteine levels).
     
    Digestive System
     
    Betaine Hydrochloride may reduce the risk of Gallstones in persons with low levels of Hydrochloric Acid (i.e. in persons afflicted with Hypochlorhydria).
    Betaine Hydrochloride may alleviate many cases of Heartburn (by increasing the level of Hydrochloric Acid in the Stomach).
     
    Betaine Hydrochloride functions as a supplemental source of Hydrochloric Acid for Hypochlorhydria patients.
    Betaine Hydrochloride may be useful for the treatment of Small Intestinal Bacterial Overgrowth Syndrome (Hypochlorhydria (lack of Hydrochloric Acid) patients have increased risk of Small Intestinal Bacterial Overgrowth Syndrome. Betaine Hydrochloride is a source of supplemental Hydrochloric Acid that may eliminate Hypochlorhydria and therefore eliminate the underlying cause of Small Intestinal Bacterial Overgrowth Syndrome). [more info]
     
    Immune System
     
    Betaine Hydrochloride may prevent and treat Allergies (insufficient production of Hydrochloric Acid in the Stomach (Hypochlorhydria) is believed to be an underlying cause of some Allergies and Betaine Hydrochloride is a supplemental source of Hydrochloric Acid).
    Betaine Hydrochloride may suppress or kill Helicobacter pylori (Hypochlorhydria (lack of Hydrochloric Acid) patients have increased levels of Helicobacter pylori – Betaine Hydrochloride is a source of supplemental Hydrochloric Acid).
     
    Metabolism
     
    Betaine may improve Athletic Performance (by improving the body’s Energy levels, increasing Stamina and improving the body’s utilization of Oxygen).
    Betaine may increase the body’s Energy levels.
    Betaine may increase the Liver’s efficiency in metabolizing Fatty Acids.
     
    Betaine may reduce elevated Homocysteine levels (during its metabolism within the body, Betaine transfers one of its Methyl Groups to Homocysteine, causing Homocysteine to be converted to Methionine; Betaine, by losing one methyl group becomes Dimethyl Glycine (DMG)).
    Betaine may detoxify and stimulate the Liver:
    Betaine may help to prevent Cirrhosis.
    Betaine may help to prevent and reverse Fatty Liver.
    Betaine may improve the body’s utilization of Oxygen.
    Betaine may increase Stamina.
     
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    TOP H
    [U1]Prebiotic that converts into a probiotic

    #2626
    AvatarEK
    Keymaster

    Con Job
     
     
    Attention: This is in no way an e-mail forgery, this is sent by the Customer Support of Verified by Visa !
    Dear Customer Verified by Visa ,
    Your credit card is temporarily suspended , Because we have noticed a problem on your carte. –We determine that someone might try to use your card without your permission. For your protection, we temporarily suspended your credit card. Pour lever cette suspension, Click here suivez la procйdure indiquer pour Update your Credit card.–Note: If this is not completed February 20, 2012, we will be forced to suspend your card !–Please note that in 50% of cases you will receive this email in the SPAM box, this is because of the increased security of emailing services you use. –We appreciate your cooperation in the context of your file.
    Thank you,
    Customer Service Support of Verified by Visa.
    Call your bank immediately before  filling out this form—I did to validate my cards activation—and you have to understand that this is a set up to go to a site and give up or out privy info–And what this will do is compromise your security—never allow this—validate before you respond
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    Zapping Food—when buying meat or poultry- or any fruits or veges – to increase the safety measures of eliminating any potential contaminant—microbes—parasites- mold fungus- bacteria—So to set a “charge “ this will neutralize whatever or burn out what may be there—so take a zapper –stunner or cattle prod and place the prods on the meat or produce and let the charge go for a moment—if the animal protein is large then do it on 2 sides-apply this to fruit and veges as well—
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    Fruit Flies Use Alcohol as a Drug to Kill Parasites
     
    If fruit flies infected with wasps tap the alcohol in rotting fruit, it raises their blood-alcohol levels and their survival rates. The alcohol doesn’t just kill some of the wasps, it essentially liquifies them. ScienceDaily (Feb. 16, 2012) — Fruit flies infected with a blood-borne parasite consume alcohol to self-medicate, a behavior that greatly increases their survival rate, an Emory University study finds.–“We believe our results are the first to show that alcohol consumption can have a protective effect against infectious disease, and in particular against blood-borne parasites,” says Todd Schlenke, the evolutionary geneticist who led the research.–“It may be that fruit flies are uniquely adapted to using alcohol as medicine,” he adds, “but our data raise an important question: Could other organisms, perhaps even humans, control blood-borne parasites through high doses of alcohol?”—-Current Biology is publishing the study, co-authored by Emory graduate student Neil Milan and undergraduate student Balint Kacsoh.-The results add to the growing body of evidence that some animals know how to use toxic substances found in nature as medicine. Drosophila melanogaster, the common fruit fly that swirls around browning bananas in your kitchen, is an important biological model system. The Schlenke lab uses D. melanogaster to study how immune systems adapt to pathogens. The fly larvae eat the rot, or fungi and bacteria, that grows on overripe, fermenting fruit. “They’re essentially living in booze,” Schlenke says. “The amount of alcohol in their natural habitat can range from 5 to 15 percent. Imagine if everything that you ate and drank all day long was 5-percent alcohol. We wouldn’t be able to live like that, but fruit flies are really good at detoxifying alcohol.”–Tiny, endoparasitoid wasps are major killers of fruit flies. The wasps inject their eggs inside the fruit fly larvae, along with venom that aims to suppress their hosts’ immune response. If the venom is effective enough, the wasp egg hatches, and the wasp larva begins to eat the fruit fly larva from the inside out. Eventually, an adult wasp emerges from the remains of the fruit fly pupa. Some fruit flies, however, can overcome the effects of wasp venom and mount an immune response against wasp eggs. The blood cells in these fly larvae swarm over the wasp eggs and release nasty chemicals to kill them, allowing the fruit fly larvae to grow into adults.–“A constant co-evolutionary battle is going on between the immune systems of the flies and the venoms of the wasps,” Schlenke says. “Any new mechanism of defense that protects flies from wasps will tend to spread through fly populations by natural selection.” Schlenke wondered if the fruit flies could be tapping the toxic effects of alcohol in their natural habitat to fight off wasps.
    To test the theory, the researchers used a bisected petri dish filled with the yeast that fruit flies are normally fed in a lab environment. The yeast on one side of the dish was mixed with 6 percent alcohol, while the yeast on the other side remained alcohol-free. The researchers then released fruit fly larvae into the dish, allowing them to freely move to either side.
    After 24 hours, 80 percent of the fruit fly larvae that were infected with wasps were on the alcohol side of the dish, while only 30 percent of the non-infected fruit fly larvae were on the alcohol side.—“The strength of the result was surprising,” Schlenke says. “The infected fruit flies really do seem to purposely consume alcohol, and the alcohol consumption correlates to much higher survival rates.” Infected fruit flies that consumed alcohol beat out the wasps in about 60 percent of the cases, compared to a 0 percent survival rate for fruit fly controls that fed on plain yeast.–“The wasps aren’t as good as the flies at handling alcohol,” Schlenke says. A developing wasp knocked out within an alcohol-consuming fly larva dies in a particularly horrible way, he adds. “The wasp’s internal organs disperse and appear to be ejected out of its anus. It’s an unusual phenotype that we haven’t seen in our wasps before,” Schlenke says.—The lab repeated the experiment using another species of wasp that specializes in laying its eggs in D. melanogaster, rather than the generalist wasp used previously. Again, 80 percent of the infected flies wound up on the alcohol side of the dish, while only 30 percent of the uninfected flies did. But the alcohol diet was far less effective against the specialist wasps, killing them in only 10 percent of the cases.—“You would expect this kind of result,” Schlenke says, “since the generalist wasp species can attack plenty of other flies, but the specialist wasps are under strong pressure to adapt to the alcohol-infused habitat of D. melanogaster.”–The researchers hope that their data will lead to more studies of how alcohol may control pathogens in other organisms, including humans.—“Although many studies in humans have shown decreased immune function in chronic consumers of alcohol, little attempt has been made to assay any beneficial effect of acute or moderate alcohol use on parasite mortality or overall host fitness following infection,” Schlenke says. Story Source- The above story is reprinted from materials provided by Emory University. Note: Materials may be edited for content and length. For further information, please contact the source cited above. Journal Reference-Neil F. Milan, Balint Z. Kacsoh, Todd A. Schlenke. Alcohol Consumption as Self-Medication against Blood-Borne Parasites in the Fruit Fly. Current Biology, 2012; DOI: 10.1016/j.cub.2012.01.045
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    Recipe with alcohol—utilize any brandy or vodka or clean alcohol beverage—then add to it wormwood or clove or black walnut extract with the beverage or balm of gilead or bee Propolis and add 3 drops
     
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    B.C. paves way for all-in-one identity card-ID to start out as more secure CareCard
     
    The B.C. government is moving forward with plans for high-tech identity cards that will one day let people access a host of provincial services on the Internet. The province intends to sign a $20-million, six-year deal with Toronto-based SecureKey to provide card reader technology, the government says. It’s the latest in a series of new laws and contracts that pave the way for expanded government Internet services.–The cards may one day be used to access government websites for electronic health records, prescription histories, age verification, driver’s licence details, electronic voting and school registration for children. Currently, you have to visit a government office in person and show appropriate ID to access such services.–Health Minister Mike de Jong announced last May the government was developing new CareCards, with improved security features, to combat the millions of dollars lost to health insurance fraud.–Those cards should be available in November, and will roll out over the next five years. They’ll be free and mandatory for all British Columbians, requiring millions of people to re-enrol into the healthcare system. The project is expected to cost the government about $150 million.–People will also have the option of combining their new CareCard and driver’s licence into one B.C. Services Card.–The new government cards will have embedded security chips, similar to certain credit cards that allow customers to wirelessly make purchases by touching or waving their credit card in front of a terminal.–The government’s contract with SecureKey will develop B.C. card readers – key-sized devices that plug into a computer’s USB port. People tap their new CareCard or Services Card onto the SecureKey reader and enter a PIN number on a government website, to authenticate their identity.—There won’t be any online government services available when the cards launch in November. The province has proposed a rollout of features from different ministries over the next five years.–B.C. said it will directly award SecureKey a contract because the company already holds a contract with the federal government and the province wants its system to be compatible with Canada’s service.—NDP critic Doug Routley said the Liberal government has a dismal track record on protecting privacy and should have asked for other bids. “I know some pretty good roofers, but I’d still get three quotes on a roof,” he said. “It’d still be prudent to put this out there for competition.”–There remains many privacy questions about the direction the government is headed, said Vince Gogolek, executive director of the B.C. Freedom of Information and Privacy Association. He said the government rushed through legislation last fall that allows for crossministry sharing of personal information needed by the new cards.—The government said it is consulting with the independent privacy commission on the technology.–Identity cards won’t store any information inside their chips, and the SecureKey readers simply create a secure path and network to approve a person’s ID and re-direct them back to government information, officials said Friday.-The cards can be remotely cancelled if lost, and will only access the minimum amount of personal information required for a service – for example, a birth date to prove an age or a health number for prescriptions.
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    Nanoparticles in Food, Vitamins Could Harm Human Health
     
    ScienceDaily (Feb. 16, 2012) — Billions of engineered nanoparticles in foods and pharmaceuticals are ingested by humans daily, and new Cornell research warns they may be more harmful to health than previously thought.—A research collaboration led by Michael Shuler, the Samuel B. Eckert Professor of Chemical Engineering and the James and Marsha McCormick Chair of Biomedical Engineering, studied how large doses of polystyrene nanoparticles — a common, FDA-approved material found in substances from food additives to vitamins — affected how well chickens absorbed iron, an essential nutrient, into their cells.–The results were reported online Feb. 12 in the journal Nature Nanotechnology. According to the study, high-intensity, short-term exposure to the particles initially blocked iron absorption, whereas longer-term exposure caused intestinal cell structures to change, allowing for a compensating uptick in iron absorption.–  The researchers tested both acute and chronic nanoparticle exposure using human gut cells in petri dishes as well as live chickens and reported matching results. They chose chickens because these animals absorb iron into their bodies similarly to humans, and they are also similarly sensitive to micronutrient deficiencies, explained Gretchen Mahler, Ph.D. ’08, the paper’s first author and former Cornell graduate student and postdoctoral associate.–The researchers used commercially available, 50-nanometer polystyrene carboxylated particles that are generally considered safe for human consumption. They found that following acute exposure, a few minutes to a few hours after consumption, both the absorption of iron in the in vitro cells and the chickens decreased.—But following exposure of 2 milligrams per kilogram for two weeks — a slower, more chronic intake — the structure of the intestinal villi began to change and increase in surface area. This was an effective physiological remodeling that led to increased iron absorption.–“This was a physiological response that was unexpected,” Mahler said.–Shuler noted that in some sense this intestinal villi remodeling was positive because it shows the body adapts to challenges. But it serves to underscore how such particles, which have been widely studied and considered safe, cause barely detectable changes that could lead to, for example, over-absorption of other, harmful compounds.–Human exposure to nanoparticles is only increasing, Shuler continued.–“Nanoparticles are entering our environment in many different ways,” Shuler said. “We have some assurance that at a gross level they are not harmful, but there may be more subtle effects that we need to worry about.”–The paper included Cornell co-authors Mandy Esch, a research associate in biomedical engineering; Elad Tako, a research associate at the Robert W. Holley Center for Agriculture and Health; Teresa Southard, assistant professor of biomedical sciences; Shivaun Archer, senior lecturer in biomedical engineering; and Raymond Glahn, senior scientist with the USDA Agricultural Research Service and courtesy associate professor in the Department of Food Science. The work was supported by the National Science Foundation; New York State Office of Science, Technology and Academic Research; Army Corp of Engineers; and U.S. Department of Agriculture.—Story Source-The above story is reprinted from materials provided by Cornell University, via Newswise. The original article was written by Anne Ju. –Journal Reference-Gretchen J. Mahler, Mandy B. Esch, Elad Tako, Teresa L. Southard, Shivaun D. Archer, Raymond P. Glahn, Michael L. Shuler. Oral exposure to polystyrene nanoparticles affects iron absorption. Nature Nanotechnology, 2012; DOI: 10.1038/nnano.2012.3
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    Building Bone from Cartilage- Orthopaedic Researchers Take the Road Less Travelled
    ScienceDaily (Feb. 14, 2012) — A person has a tumor removed from her femur. A soldier is struck by an improved explosive device and loses a portion of his tibia. A child undergoes chemotherapy for osteosarcoma but part of the bone dies as a result. Every year, millions of Americans sustain fractures that don’t heal or lose bone that isn’t successfully grafted. But a study presented at the Orthopaedic Research Society (ORS) 2012 Annual Meeting in San Francisco offers new hope for those who sustain these traumas.  Orthopaedic researchers with the University of California, San Francisco (UCSF), Orthopaedic Trauma Institute, have found a very promising, novel way to regenerate bone. “Cartilage graft induces bone that actually integrates with the host bone and vascularizes it,” said Ralph S. Marcucio, PhD, Associate Professor, UCSF School of Medicine.–Cartilage graft is very different than the current methods used for bone grafting — autograft bone (a person’s own bone) or allograft materials (donor bone). For various reasons, these two grafting techniques can result in poor graft integration and osteonecrosis.—“With millions of bone grafting procedures performed every year in just the United States, developing improved technologies could directly enhance patient care and clinical outcomes,” Dr. Marcucio said.–Chelsea S. Bahney, PhD, Postdoctoral Scholar, UCSF School of Medicine, concedes their approach is less orthodox. “It is not the pathway that most people think about, but it made a lot more sense to follow the normal developmental mechanism.””This cartilage is naturally bioactive. It makes factors that help induce vascularization and bone formation,” added Dr. Bahney. “When people use a bone graft, it is often dead bone which requires something exogenous to be added to it or some property of the matrix in the graft.” Through a process called endochondral ossification, cartilage grafts produce new tissue that is very similar to the person’s own bone. Without additional properties to it, the researchers found the cartilage graft integrated well and was fully vascularized.–“We’re just taking a very similar cartilage that can induce bone formation, putting it into a bone defect and letting it just do its thing,” Dr. Marcucio said.—In the study, the researchers chose a non-stabilized tibial fracture callus as a source of a cartilage graft. “Healing of the transplanted cartilage grafts supported our hypothesis by producing a well-vascularized bone that integrated well with the host,” Dr. Bahney said.–“A cartilage graft could offer a promising alternative approach for stimulating bone regeneration,” Dr. Marcucio said. “Future work will focus on developing a translatable technology suitable for repairing bone through a cartilage intermediate at a clinical level.”–Story Source–The above story is reprinted from materials provided by Orthopaedic Research Society (ORS).
     
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    HOME
     
    Show of the Week March 5 2012
     
    Scientists Prepare Test-tube Burger
     
    300,000 Organic Farmers Sue Monsanto in Federal Court
    Decision on March 31st to Go to Trial
     
    Secret GPS tracker terrifies Ontario man
     
    New Ability to Regrow Blood Vessels Holds Promise for Treatment of Heart Disease
     
    Colon Cleanse
     
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    Scientists Prepare Test-tube Burger
    CLIVE COOKSON – Financial Times (U.K.)
    I think there is going to be a tremendous emphasis on this. It will become a growing trend, because industrial cattle operations are going to become unprofitable due to the rising cost of water as it becomes scarcer. It takes 1,300 gallons of water to produce an eight ounce hamburger. As affluence increases across the world — not to be confused with wealth, only more than subsistence — eating meat will increase. The demands for ! water and grain (and the water it requires) will become unsustainable. The world’s first test-tube hamburger, created in a Dutch laboratory by growing muscle fibres from bovine stem cells, will be ready to grill in October, scientists believe.–‘I am planning to ask Heston Blumenthal [the celebrity chef] to cook it,” Mark Post, leader of the artificial meat project at Maastricht University in the Netherlands, told the American Association for the Advancement of Science annual meeting in Vancouver.–Researchers believe that meat grown in factories, rather than on farms, will be a more sustainable and less environmentally harmful source of food. Live cattle and pigs are only 15 per cent efficient at converting vegetable proteins to meat from the grass and cereals they eat.–
    ‘If we can raise the efficiency from 15 to 50 per cent by growing meat in the lab, that would be a tremendous leap forward,” Professor Post said.—Starting with bovine stem cells, the Dutch researchers have grown muscle fibres up to 3cm long and 0.5mm thick. The fibres are tethered and exercised as they grow, like real muscles, by bending and stretching in the culture dishes. They feed on a broth of vegetable proteins and other nutrients, equivalent to the grass or grain diet of cattle.—At present the fibres are a pallid yellowish-pink colour, rather than the red of raw ground beef, because they do not contain blood, but Prof Post plans to improve their appearance.–Patrick Brown, biochemistry professor at Stanford University in California, told the AAAS that global meat consumption was expected to double by 2050, yet livestock farming already accounted for 18 per cent of man-made greenhouse gas emissions and threatened biodiversity worldwide.–
    To provide fat, an essential element in real burgers, They will be minced in with bovine fat cells are also being grown in the lab.the muscle fibres.—
    This project was started about six years ago, and I expect it will be another 10 to 20 years before we can mass-produce our meat,” Prof Post said.
    An anonymous individual has financed the Maastricht project with a €250,000 grant. He is expected to contribute further funds after the planned production of a ‘proof of concept” burger from the lab-grown muscle in October.
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    300,000 Organic Farmers Sue Monsanto in Federal Court: Decision on March 31st to Go to Trial
    The GMO movement is perhaps the leading example in our culture of how the greed of a single corporation can destabilize and entire ecosystem, thus effecting the lives of millions; all so a small group of people already rich can get richer. Nelson states, ‘Corporate control of our food system has led to the loss of millions of family farmers, destruction of our soil…”-Hundreds of citizens, (even including NYC chefs in their white chef hats) joined Occupy the Food System groups, ie Food Democracy  Now, gathered outside the Federal Courts in Manhattan on January 31st, to support organic family farmers in their landmark lawsuit against Big Agribusiness giant Monsanto. (Organic Seed Growers & Trade Association v. Monsanto) Oral arguments were heard that day concerning the lawsuit by 83 plaintiffs representing over 300,000 organic farmers, organic seed growers, and organic seed businesses.—The lawsuit addresses the bizarre and shocking issue of Monsanto harassing and threatening organic farmers with lawsuits of ‘patent infringement” if any organic farmer ends up with any trace amount of GM seeds on their organic farmland. Judge Naomi Buckwald heard the oral arguments on Monsanto’s Motion to Dismiss, and the legal team from Public Patent Foundation represented the rights of American organic farmers against Monsanto, maker of GM seeds, [and additionally, Agent Orange, dioxin, etc.]—After hearing the arguments, Judge Buckwald stated that on March 31st she will hand down her decision on whether the lawsuit will move forward to trial.–Not only does this lawsuit debate the issue of Monsanto potentially ruining the organic farmers’ pure seeds and crops with the introduction of Monsanto’s genetically modified (GM) seeds anywhere near the organic farms, but additionally any nearby GM fields can withstand Monsanto’s Roundup herbicides, thus possibly further contaminating the organic farms nearby if Roundup is used.—Of course, the organic farmers don’t want anything to do with that ole contaminated GM seed in the first place. In fact, that is why they are certified organic farmers. But now they have to worry about getting sued by the very monster they abhor, and even have to spend extra money and land (for buffers which only sometimes deter the contaminated seed from being swept by the wind into their crop land). At this point, they are even having to resort to not growing at all the following organic plants: soybeans, corn, cotton, sugar beets, and canola, …just to protect themselves from having any (unwanted) plant that Monsanto could possibly sue them over.
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    Secret GPS tracker terrifies Ontario man
    An Ontario man says he’s angry and frightened after discovering someone hid a GPS tracking device under his vehicle, apparently to secretly monitor his movements.—“I was doing just a regular inspection on my truck and I found this black box under my truck … with flashing lights inside,” Ben Ferrill of Warsaw, Ont., told Go Public. “I didn’t know what it was. I didn’t know if it was a bomb. We were scared to death … It felt like a movie — unreal.”—After making the discovery last fall he reported it the next morning to the Ontario Provincial Police. Ferrill said the OPP tried to find out whom the device belonged to to lay a mischief charge, but were stymied in their investigation.—“I feel powerless. I can’t do anything about it and I really wish the police did more. I really wish they would do more — and I’m upset,” Ferrill said. Ferrill said he and his wife haven’t been able to sleep properly since, because they are worried someone is watching them. “We spent lots of nights up until three in the morning crying and talking about it — not sleeping and looking out the windows and being suspicious of vehicles that drive by,” Ferrill said. “Are they following me? Are they watching me? Are they going to try to do something to me? Are they going to try to do something to our family? The fear in finding something like that is unreal.”Ferrill’s lawyer, Ian Wilson, said is illegal to put a tracking device on someone else’s vehicle without their knowledge or consent unless there is a search warrant.—“The trouble is, we don’t know who is behind this,” Wilson said.  The device Ferrill found, Wilson said, was sold by an American company, U.S. Fleet Tracking, which sells GPS systems to companies that want to track their fleet vehicles. The OPP obtained a production order, compelling the Canadian company that provides the wireless connection, Kore Wireless, to disclose whose device it is. However, Kore said it didn’t have that information. “I’ve [also] tried to get answers from Kore Wireless and their lawyer but they will tell me nothing,” Wilson said. Kore Wireless president Alex Brisbourne told CBC News his company only provides “connectivity. We don’t know who the end user is.”He said U.S. Fleet bills the customer and gives access to its website, where the customer can track its fleet vehicles in real time. “Our customer [U.S. Fleet] is in the United States. They have no responsibility or accountability to provide that information [to Canadian police],” Brisbourne said. When asked whether he requested the customer information from U.S. Fleet in this case, Brisbourne replied it “is not appropriate for us to ask for that. Security of information is particularly critical.” U.S. Fleet’s website makes it clear the company does not give up information easily, even to American authorities. “U.S. Fleet Tracking will not under any circumstance make your information or any data specific to your vehicle tracking account available to any third party — including local, state or federal law enforcement authorities … Even if presented with a court order, we promise to fight the courts to keep this information private and respect the privacy of our paying customers,” the website reads.
    Wilson and Ferrill said the OPP told them it would be too expensive and time-consuming to pursue the case through U.S. courts. The OPP told CBC News the file is now closed.–Ferrill insisted the device could not have been put there by his wife or any family member. In addition, U.S. Fleet sells to to businesses, not individuals.–He said the only dispute he is involved in is with his former employer, a car dealership in Peterborough, Ont.–Ferrill worked for a decade as a mechanic for Holiday Ford Lincoln. Two years ago, he injured his shoulder on the job. The Workplace Safety and Insurance Board (WSIB) in Ontario said he needed to be on light, restricted duty for several months.–After a few months, Holiday Ford fired him for allegedly stealing a bottle of windshield washer fluid.–A WSIB investigation found it was a pretext – that Ferrill had been fired because he was injured, which is a violation of the law. The WSIB report concluded: “A breach of their re-employment obligation has occurred.”Holiday Ford is appealing that decision, but it faces significant fines if the ruling stands. It is also facing a wrongful-dismissal lawsuit filed by Ferrill.–The company has denied Ferrill’s allegations in court filings.–Ferrill said he discovered the GPS device a few months after filing his lawsuit. He and his lawyer said they suspect the dealership could be involved, but they have no way of proving or disproving that.–CBC News left several messages with Ferrill’s former manager at Holiday Ford, but received no reply.–He has no idea how long it was there, and said the combined stress has pushed his family to the edge.–“Losing my job was really stressful, and then this is just a part of more stress,” Ferrill said. “It’s really testing our family. It’s the most stress and discomfort we have ever had.” Ferrill and his lawyer want Canadians to realize how technology can now be used against them and — at least in this case —there is no recourse.“It’s extremely frustrating to know that [customer] information exists in the U.S. somewhere … and we simply can’t get at it,” Wilson said. “[Ferrill] hasn’t had any peace of mind for the last 2½ years since he lost his job.”–Wilson said he finds it ironic this is happening to his client at the same time the federal government is talking about allowing police to monitor people’s internet use without a warrant.–“The same federal government that is responsible for this crime bill is also responsible for these wireless companies,” Wilson said.—He said he believes wireless companies in Canada should be required by law to know who the end users of the technology are: “This is a changing environment and steps have to be taken to protect people.” “We want to know who put this on our truck and why,” Ferrill said. “I’m sure whoever did this wants to do some type of harm to me, because whoever did this wants to know what I am doing all the time and wants to follow me for some reason.”
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    New Ability to Regrow Blood Vessels Holds Promise for Treatment of Heart Disease
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    Hindlimb ischemia was created in rats and treatments were delivered over seven days with an osmotic pump. The laser doppler imaging above shows the rat’s hind limb prior to treatment (on the left) and with increased blood flow (image on the right) just seven days after treatment.
    ScienceDaily (Feb. 16, 2012) — University of Texas at Austin researchers have demonstrated a new and more effective method for regrowing blood vessels in the heart and limbs — a research advancement that could have major implications for how we treat heart disease, the leading cause of death in the Western world.—The treatment method developed by Cockrell School of Engineering Assistant Professor Aaron Baker could allow doctors to bypass surgery and instead repair damaged blood vessels simply by injecting a lipid-incased substance into a patient. Once inside the body, the substance stimulates cell growth and spurs the growth of new blood vessels from pre-existing ones.—Aaron Baker is an assistant professor in the Department of Biomedical Engineering.—The method has been tested successfully on rats, and findings of the study were published recently in the Proceedings of the National Academy of Sciences –“Others have tried using growth factors to stimulate vessel growth in clinical trials and have not been successful,” said Baker, a faculty member in the school’s Department of Biomedical Engineering. “We think that a major reason for this is that previous methods assumed that the diseased tissues retained the ability to respond to a growth stimulus. Our method basically delivers extra components that can restore growth factor responsiveness to the tissue of patients with long-standing clinical disease.”— The ability to regrow blood vessels could prove crucial to treating chronic myocardial ischemia disease, which affects up to 27 million patients in the U.S. and leads to a reduction of blood flow in the heart and lower limbs — ultimately causing organ dysfunction and failure.–Central ischemia, which affects the heart, occurs when the coronary vessels that feed blood to the heart become blocked or narrow because of a buildup of fatty deposits called plaques. Such plaques are typically the result of a prolonged unhealthy diet or smoking, and factors such as age, high blood pressure and diabetes increase the risks of the disease, Baker said.
    Doctors have typically treated ischemia by physically opening the closed artery with a stent or surgically rerouting blood flow to the poorly perfused tissue. Both methods have limitations, however, and are not effective long-term.–The new method introduced by Baker and his research team builds on a promising revascularization approach that, up until now, has shown limited efficacy in clinical trials for treating human disease.—The method combines a growth factor — a substance capable of stimulating cellular growth, proliferation and cellular differentiation, as well as healing wounds — known as fibroblast growth factor 2 (FGF-2) with a lipid-embedded receptor to enhance its activity.—A challenge for scientists and engineers, however, has been getting FGF-2 to bind with cell receptors — the very molecules often found on the surface of the cell that receive chemical signals and direct activity in the cell from outside sources.—To overcome this, Baker’s method embeds the growth factors in synthetic lipid-based nanoparticles containing a coreceptor known as syndecan-4. The nanoparticles containing co-receptors that, when delivered with the growth factor, enable improved cell binding so that the growth factor can direct the targeted cell to divide, proliferate and form new cells for tissue regrowth.—The incased substance was injected into rats with hindlimb ischemia and stimulated a complete recovery from the ischemia in just seven days.—“We hope this research will increase our understanding of how tissues become resistant to revascularization therapies and may lead to more effective treatments for this widespread and debilitating disease,” said Baker, who was recognized last year with the National Institutes of Health Director’s New Innovator Award.-Story Source—The above story is reprinted from materials provided by University of Texas at Austin. -Journal Reference-E. Jang, H. Albadawi, M. T. Watkins, E. R. Edelman, A. B. Baker. Syndecan-4 proteoliposomes enhance fibroblast growth factor-2 (FGF-2)-induced proliferation, migration, and neovascularization of ischemic muscle. Proceedings of the National Academy of Sciences, 2012; 109 (5): 1679 DOI: 10.1073/pnas.1117885109
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    Colon Cleanse–
    add the whites of the Citrus -about 8 slices- then add 1 whole apple- add a pectin capsule ( if you wish not mandatory ) add bht 1 capsule-or any other antioxidant you see fit to add–example vitamin C-add sodium alginate 1 tsp  -tumeric 1 tsp- bromelain powder or capsule  1 tablespoon -add 1/8 cup of water and allow to blend at slow to medium speed til it gelatinizes–once this is done pour into a glass container and consume several tsp through out the day and use a good load of water—this will bind to metals-toxins-will support the liver-digestive system-and potentially reduce fatty deposits in the gall bladder and liver
     
     
     
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    Show Of The Week March  9 2012
     
    Food Fried in Olive or Sunflower Oil Is Not Linked to Heart Disease
     
    Stronger Intestinal Barrier May Prevent Cancer in the Rest of the Body
     
    Boosting Longevity With Good Bacteria
    The effect of hydro alcoholic Nettle (Urtica dioica) extracts on insulin sensitivity and some inflammatory indicators in patients with type 2 diabetes-
    What are you to do if you have a heart attack While you are alone
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    Food Fried in Olive or Sunflower Oil Is Not Linked to Heart Disease
    ScienceDaily (Jan. 24, 2012) — Eating food fried in olive or sunflower oil is not linked to heart disease or premature death, finds a paper published in the British Medical Journal online (bmj.com).-The authors stress, however, that their study took place in Spain, a Mediterranean country where olive or sunflower oil is used for frying and their results would probably not be the same in another country where solid and re-used oils were used for frying.–In Western countries, frying is one of the most common methods of cooking. When food is fried it becomes more calorific because the food absorbs the fat of the oils.–While eating lots of fried food can increase some heart disease risk factors such as high blood pressure, high cholesterol and obesity, a link between fried food and heart disease has not been fully investigated.—So the authors, led by Professor Pilar Guallar-Castillón from Autonomous University of Madrid, surveyed the cooking methods of 40,757 adults aged 29 to 69 over an 11-year period. None of the participants had heart disease when the study began. Trained interviewers asked participants about their diet and cooking methods. Fried food was defined as food for which frying was the only cooking method used. Questions were also asked about whether food was fried, battered, crumbed or sautéed.–The participants’ diet was divided into ranges of fried food consumption, the first quartile related to the lowest amount of fried food consumed and the fourth indicated the highest amount.–During the follow-up there were 606 events linked to heart disease and 1,134 deaths.—The authors conclude: “In a Mediterranean country where olive and sunflower oils are the most commonly used fats for frying, and where large amounts of fried foods are consumed both at and away from home, no association was observed between fried food consumption and the risk of coronary heart disease or death.”–In an accompanying editorial, Professor Michael Leitzmann from the University of Regensburg in Germany, says the study explodes the myth that “frying food is generally bad for the heart” but stresses that this “does not mean that frequent meals of fish and chips will have no health consequences.” He adds that specific aspects of frying food are relevant, such as the type of oil used.—Story Source- The above story is reprinted from materials provided by BMJ-British Medical Journal. Journal References-P. Guallar-Castillon, F. Rodriguez-Artalejo, E. Lopez-Garcia, L. M. Leon-Munoz, P. Amiano, E. Ardanaz, L. Arriola, A. Barricarte, G. Buckland, M.-D. Chirlaque, M. Dorronsoro, J.-M. Huerta, N. Larranaga, P. Marin, C. Martinez, E. Molina, C. Navarro, J. R. Quiros, L. Rodriguez, M. J. Sanchez, C. A. Gonzalez, C. Moreno-Iribas. Consumption of fried foods and risk of coronary heart disease: Spanish cohort of the European Prospective Investigation into Cancer and Nutrition study. BMJ, 2012; 344 (jan23 3): e363 DOI: 10.1136/bmj.e363—M. F. Leitzmann, T. Kurth. Fried foods and the risk of coronary heart disease. BMJ, 2012; 344 (jan23 3): d8274 DOI: 10.1136/bmj.d8274
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    Stronger Intestinal Barrier May Prevent Cancer in the Rest of the Body
    ScienceDaily (Feb. 21, 2012) — A leaky gut may be the root of some cancers forming in the rest of the body, a new study published online Feb. 21 in PLoS ONE by Thomas Jefferson University researchers suggests.—It appears that the hormone receptor guanylyl cyclase C (GC-C) — a previously identified tumor suppressor that exists in the intestinal tract — plays a key role in strengthening the body’s intestinal barrier, which helps separate the gut world from the rest of the body, and possibly keeps cancer at bay. Without the receptor, that barrier weakens.—A team led by Scott Waldman, M.D., Ph.D., chair of the Department of Pharmacology and Experimental Therapeutics at Jefferson and director of the Gastrointestinal Cancer Program at Jefferson’s Kimmel Cancer Center, discovered in a pre-clinical study that silencing GC-C in mice compromised the integrity of the intestinal barrier. It allowed inflammation to occur and cancer-causing agents to seep out into the body, damaging DNA and forming cancer outside the intestine, including in the liver, lung and lymph nodes.—Conversely, stimulating GC-C in intestines in mice strengthened the intestinal barrier opposing these pathological changes.—A weakened intestinal barrier has been linked to many diseases, like inflammatory bowel disease, asthma and food allergies, but this study provides fresh evidence that GC-C plays a role in the integrity of the intestine. Strengthening it, the team says, could potentially protect people against inflammation and cancer in the rest of the body.–“If the intestinal barrier breaks down, it becomes a portal for stuff in the outside world to leak into the inside world,” said Dr. Waldman. “When these worlds collide, it can cause many diseases, like inflammation and cancer.”–The role of GC-C outside the gut has remained largely elusive. Dr. Waldman and his team have previously shown its role as a tumor suppressor and biomarker that reveals occult metastases in lymph nodes. They’ve used to it better predict cancer risk, and have even shown a possible correlation with obesity.—Reporting in the Journal of Clinical Investigation, Dr. Waldman colleagues found that silencing GC-C affected appetite in mice, disrupting satiation and inducing obesity. Conversely, mice who expressed the hormone receptor knew when to call it quits at mealtime.–However, its role in intestinal barrier integrity, inflammation, and cancer outside the intestine is new territory in the field. A new drug containing GC-C is now on the verge of hitting the market, but its intended prescribed purpose is to treat constipation.–This study helps lays the groundwork, Dr. Waldman said, for future pre-clinical and clinical studies investigating GC-C’s abilities beyond those treatments in humans, including prevention and treatment of inflammatory bowel disease and cancer.”We’ve shown that when you pull away GC-C in animals, you disrupt the intestinal barrier, putting them at risk for getting inflammatory bowel disease and cancer. And when you treat them with hormones that activate GC-C it helps strengthen the integrity of the intestinal barrier,” Dr. Waldman said. “Now, if you want to prevent inflammation or cancer in humans, then we need to start thinking about feeding people hormones that activate GC-C to tighten up the barrier.”–Story Source–The above story is reprinted from materials provided by Thomas Jefferson University, via Newswise. —Journal References—Jieru Egeria Lin, Adam Eugene Snook, Peng Li, Brian Arthur Stoecker, Gilbert Won Kim, Michael Sullivan Magee, Alex Vladimir Mejia Garcia, Michael Anthony Valentino, Terry Hyslop, Stephanie Schulz, Scott Arthur Waldman. GUCY2C Opposes Systemic Genotoxic Tumorigenesis by Regulating AKT-Dependent Intestinal Barrier Integrity. PLoS ONE, 2012; 7 (2): e31686 DOI: 10.1371/journal.pone.0031686–Michael A. Valentino, Jieru E. Lin, Adam E. Snook, Peng Li, Gilbert W. Kim, Glen Marszalowicz, Michael S. Magee, Terry Hyslop, Stephanie Schulz, Scott A. Waldman. A uroguanylin-GUCY2C endocrine axis regulates feeding in mice. Journal of Clinical Investigation, 2011; 121 (9): 3578 DOI: 10.1172/JCI57925
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    Boosting Longevity With Good Bacteria
    ScienceDaily (Jan. 22, 2012) — A diet supplemented with a specific probiotic bacterial strain increases the lifespan of mice.—The mammalian gut is home to hundreds of bacterial species that contribute to food digestion and, in some cases, inflammatory gut diseases. Probiotics, beneficial bacterial species, can enhance gut health by keeping the resident bacteria in check. Now, a team of researchers at the RIKEN Innovation Center in Wako, including Mitsuharu Matsumoto, report that administration of the probiotic bacterial strain Bifidobacterium animalis subspecies lactis LKM512 to mice can lengthen their lifespan. Matsumoto and colleagues previously showed that LKM512 could reduce inflammatory markers in elderly humans and modify the makeup of intestinal bacteria2, but the effects of it on lifespan still required investigation. After starting 10-month-old mice on a diet including LKM512 for 11 months, the researchers found that LKM512-treated mice lived longer, had fewer skin lesions, and had better hair quality than untreated mice. Analyses of the gut of these mice revealed elevated gene expression in some bacterial species compared with control mice, indicating that LKM512 may improve gut health indirectly by regulating the levels of other bacterial species. The LKM512 treatment also prevented some age-related changes in bacterial composition of the gut, suggesting that the probiotic treatment protects the gut from developing characteristics associated with aging.—Acting as a barrier between the bacteria and food within the gut and the rest of the human body is an important role of the gut lining. Breakdown of this lining can cause infectious or inflammatory diseases. The researchers found that the gut of LKM512-treated mice served as a stronger barrier than the gut of control mice. LKM512 seemed to perform this function by increasing the expression of various proteins that maintain the tight connection between gut epithelial cells.-Polyamines are chemicals that reduce inflammation, and their levels decrease as an individual ages. Matsumoto and colleagues observed increases in intestinal polyamine levels in LKM512-treated mice, which may be caused by the greater numbers of bacteria promoted by LKM512. The increase in polyamines caused by LKM512 appeared to reduce inflammation in the body of the mice, as inflammatory markers in the blood and urine were lower in LKM512-treated mice compared with controls. In aged mice treated with LKM512, inflammatory marker levels were similar to those observed in younger mice, indicating that adults can benefit from probiotics.—“In future work, we hope to clarify the effectiveness of LKM512 in humans,” explains Matsumoto. If the findings extend to humans, inclusion of LKM512 into the human diet could enhance overall health and increase the human lifespan.—Story Source-The above story is reprinted from materials provided by RIKEN, via ResearchSEA.
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    The effect of hydro alcoholic Nettle (Urtica dioica) extracts on insulin sensitivity and some inflammatory indicators in patients with type 2 diabetes-
    Pak J Biol Sci. 2011 Aug 1;14(15):775-9-Authors: Namazi N, Esfanjani AT, Heshmati J, Bahrami A
    Abstract
    Type 2 diabetes is a metabolic disorder that is strongly associated with cardiovascular risk. Inflammation is a potential risk factor for cardiovascular disease. In this study, hydro alcoholic extract of Nettle (Urtica dioica) on insulin sensitivity and some inflammatory indicators in type 2 diabetic patients were studied. A randomized double-blind clinical trial on 50 men and women with type 2 diabetes was done for 8 weeks. Patients were adjusted by age, sex and duration of diabetes, then randomly divided into two groups, an intervention and control group. They received, 100 mg kg-1nettle extract or placebo in three portions a day for 8 weeks. Interleukin 6 (IL-6), Tumor Necrosis Factor-alpha (TNF-alpha), High Sensitive C-Reactive protein (hs-CRP) and Fasting Insulin concentration were measured. Insulin Sensitivity was calculated, at the beginning and the end of the study. The data were analyzed by SPSS version 18, p<0.05 was considered significant for all variables. After 8 weeks, IL-6 and hs-CRP showed a significant decrease in the intervention group compared to the control group (p<0.05). The findings showed that the hydro alcoholic extract of nettle has decreasing effects on IL-6 and hs-CRP in patients with type 2 diabetes after eight weeks intervention.–PMID: 22303583 [PubMed – indexed for MEDLINE]
    How to prepare this—take equal parts of either wine or vodka-or tequila or grappa Add to the slow cooker-then add equal portion of distilled water or RO water-NEVER TAP WATER—allow it to simmer for 3 days—strain it  and bottle it and use it accordingly—measure off your body weight and go from there as it is stated in the comments—take your weight divide by 2.2 and then mutiply by 100mg this will give dosing for your body weight so in the case of a 180 lb person—they would go 180/2.2-=== 81 kgs then multiply by 100 and you get 8100 mgs or 8.1 grams which a teaspoon holds 5 grams so you would either do a tsp and a half+ or do more dosing qith just the one teaspoon—say you take one dose several times in his case 1. ½ + 3 times a day orr 1 tsp 5 times a day—so approximate on how you want to utilize this—
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    What are you to do if you have a heart attack While you are alone.
     
    The Johnson City Medical Center staff actually Discovered this and did an in-depth study On it in our ICU. The two individuals that discovered this then did An article on it, had it published and have had it incorporated into ACLS and CPR classes. It is very true and has and does work. It is called cough CPR. A cardiologist says it’s the truth If everyone who gets this sends it to 10 people,
    You can bet that we’ll save at least one life. It could save your life Let’s say it’s 6:15 p.m. And you’re driving home (alone of course), after an usually hard day on the job. You’re really tired, upset and frustrated. Suddenly you start experiencing severe pain In your chest that starts to radiate out Into your arm and up into your jaw. You are only about five miles from the hospital Nearest your home. Unfortunately you don’t know if you’ll be Able to make it that far. What can you do? You’ve been trained in CPR But the guy that taught the course didn’t tell You what to do if it happened to yourself Since many people are alone when they suffer a heart attack, this article seemed to be in order. Without help, the person whose heart is beating improperly and who begins to feel faint, Has only about 10 seconds left before losing consciousness. However, these victims can help themselves by coughing repeatedly and very vigorously. A deep breath should be taken before each Cough, and the cough must be deep And prolonged, as when producing sputum From deep inside the chest. A breath and a cough must be repeated About every two seconds without let up Until help arrives, or until the heart is felt to be beating normally again. Deep breaths get oxygen into the lungs and coughing movements squeeze the heart and Keep the blood circulating. The squeezing pressure on the heart also helps it regain normal rhythm. In this way, heart attack victims can get to a hospital. Tell as many other people as possible about this, it could save their lives! From Health Cares, Rochester General Hospital via Chapter 240s newsletter ‘AND THE BEAT GOES ON ‘ (reprint from The Mended Hearts, Inc. Publication, Heart Response
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    Show of the Week March 12 2012
     
    Pfizer snaps up Emergen-C vitamin C maker
    Researchers Test Sugary Solution to Alzheimer’s Disease
     
    Stopping Hormone Therapy Might Help Breast Cancer to Regress
     
    Potential ‘Safe Period’ For Hormone Replacement Use Identified
     
    Long-Term Estrogen Therapy Linked To Breast Cancer Risk
     
    Estrogen Therapy May Be Associated With Kidney Stones in Postmenopausal Women
     
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    Pfizer snaps up Emergen-C vitamin C maker 28-Feb-2012Drug giant Pfizer Inc. has added Alacer Corp., maker and distributor of Emergen-C products, to its Consumer Healthcare division.Financial terms of the transaction were not disclosed, but Alacer says it produces almost 500 million packets of Emergen-C annually, with products sold in health food stores, supermarkets, drug stores, mass merchandisers and club stores nationwide. We are very pleased that the Emergen-C family of products will become part of Pfizer’s portfolio  said Paul Sturman, President of Pfizer Consumer Healthcare. We expect that our global network and deep expertise in dietary supplements combined with our desire to provide consumers with high-quality products will make Emergen-C more accessible than it has ever been before Emergen-C products add to and greatly complement our market-leading dietary supplement portfolio–Market Sales of vitamin C supplements – the biggest single category in the vitamins and minerals market – were up 2.8% to $221.27m in the year to October 1 across conventional and natural channels combined—While vitamin C sales were down 2.4% in the natural channel (natural supermarkets excluding Whole Foods) to $31.43m, they were up 3.7% in the conventional channel (FDMx) to $189.85m. In January, Pfizer CEO Ian Read told attendees at the JP Morgan Healthcare Conference in San Francisco that the company was still planning to offload its $1.87bn nutrition division, with Nestlé, Danone, Abbott Laboratories and Heinz still in the running. Last year, Pfizer agreed to sell hard-capsule manufacturer Capsugel for $2.375 billion in cash to an affiliate of Kohlberg Kravis Roberts &amp; Co L.P. (KKR). A spokesperson for Pfizer told NutraIngredients-USA.com: “The acquisition of Alacer Corp., will fall within Pfizer’s Consumer Healthcare business. As such, this doesn’t impact the evaluation of strategic options for our Nutrition business. “We have said that we would continue to pursue bolt-on business development activities that support our strategies. For example, in December 2011, we acquired Ferrosan’s consumer healthcare business, which strengthens our presence in dietary supplements as well as expand our footprint –Unique opportunity Ron Fugate, President and CEO of Alacer said that being acquired by Pfizer marked “the beginning of an exciting new chapter for Alacer and the Emergen-C health and wellness brand. By becoming part of Pfizer, we can access the resources and reach that will help us support healthy, active lifestyles across the globe.”
     
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    Researchers Test Sugary Solution to Alzheimer’s Disease
    ScienceDaily (Feb. 28, 2012) — Slowing or preventing the development of Alzheimer’s disease, a fatal brain condition expected to hit one in 85 people globally by 2050, may be as simple as ensuring a brain protein’s sugar levels are maintained.–That’s the conclusion seven researchers, including David Vocadlo, a Simon Fraser University chemistry professor and Canada Research Chair in Chemical Glycobiology, make in the latest issue of Nature Chemical Biology.-The journal has published the researchers’ latest paper “Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation.”Vocadlo and his colleagues describe how they’ve used an inhibitor they’ve chemically created — Thiamet-G — to stop O-GlcNAcase, a naturally occurring enzyme, from depleting the protein Tau of sugar molecules.-“The general thinking in science,” says Vocadlo, “is that Tau stabilizes structures in the brain called microtubules. They are kind of like highways inside cells that allow cells to move things around.”—Previous research has shown that the linkage of these sugar molecules to proteins, like Tau, in cells is essential. In fact, says Vocadlo, researchers have tried but failed to rear mice that don’t have these sugar molecules attached to proteins.—Vocadlo, an accomplished chess player in his spare time, is having great success checkmating troublesome enzymes with inhibitors he and his students are creating in the SFU chemistry department’s Laboratory of Chemical Glycobiology.–Research prior to Vocadlo’s has shown that clumps of Tau from an Alzheimer brain have almost none of this sugar attached to them, and O-GlcNAcase is the enzyme that is robbing them.—Such clumping is an early event in the development of Alzheimer’s and the number of clumps correlate with the disease’s severity.–Scott Yuzwa and Xiaoyang Shan, grad students in Vocadlo’s lab, found that Thiamet-G blocks O-GlcNAcase from removing sugars off Tau in mice that drank water with a daily dose of the inhibitor. Yuzwa and Shan are co-first authors on this paper.—The research team found that mice given the inhibitor had fewer clumps of Tau and maintained healthier brains.–“This work shows targeting the enzyme O-GlcNAcase with inhibitors is a new potential approach to treating Alzheimer’s,” says Vocadlo. “This is vital since to date there are no treatments to slow its progression.–“A lot of effort is needed to tackle this disease and different approaches should be pursued to maximize the chance of successfully fighting it. In the short term, we need to develop better inhibitors of the enzyme and test them in mice. Once we have better inhibitors, they can be clinically tested. Story Source-The above story is reprinted from materials provided by Simon Fraser University. —Journal Reference-Scott A Yuzwa, Xiaoyang Shan, Matthew S Macauley, Thomas Clark, Yuliya Skorobogatko, Keith Vosseller, David J Vocadlo. Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation. Nature Chemical Biology, 2012; DOI: 10.1038/nchembio.797
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    Stopping Hormone Therapy Might Help Breast Cancer to Regress
    ScienceDaily (Feb. 28, 2012) — As soon as women quit hormone therapy, their rates of new breast cancer decline, supporting the hypothesis that stopping hormones can lead to tumor regression, according to a report e-published in Cancer Epidemiology, Biomarkers, & Prevention.—As part of the national Breast Cancer Surveillance Consortium, researchers studied 741,681 woman-years of data (with a median of 3.3 years per woman) on 163,490 women aged 50-79 who were Group Health Cooperative members and had no prior history of breast cancer.–“This is the first study to look over time at screening mammography use among individual women by their hormone therapy status linked with their breast cancer diagnoses,” said lead author Diana S.M. Buist, PhD, a senior investigator at Group Health Research Institute.–Previous research has shown a rapid decline in new breast cancers — and also in use of hormone therapy and of screening mammography — since 2002, when the Women’s Health Initiative published that breast cancer rates were higher in women taking estrogen and progestin than in those taking either a placebo or only estrogen.—Some have suggested that the decline in use of hormone therapy may have caused the fall in the breast cancer rate, perhaps by making tumors regress, Dr. Buist explained. But others have countered that the explanation for the declines in both breast cancer and hormone use might instead be that because former hormone users are less concerned about breast cancer or see their doctors less often, they may get less screening mammography than do women who have never taken hormones.–“We set out to test this idea,” Dr. Buist said, “and our results seem to refute it.” Before 2002, former users of hormone therapy had lower rates of screening mammography than did current users. “But we found that this is no longer true,” she said. Indeed, former users had the same or even slightly higher screening rates than current users.—“We concluded that differences in rates of screening mammography don’t explain the declines in rates of the incidence of invasive breast cancer among women who’ve stopped using hormone therapy, Dr. Buist said. The National Cancer Institute, which supports the Breast Cancer Surveillance Consortium, funded this study. The collection of cancer data was also supported in part by several state public health departments and cancer registries throughout the United States.—In addition to Dr. Buist, the other co-authors were Diana L. Miglioretti, PhD, Rod Walker, MS, and Erin J. Aiello Bowles, MPH, of Group Health Research Institute; Walter Clinton, PhD, of Veterans Affairs (VA) Puget Sound Healthcare System; Patricia A. Carney, PhD, of Oregon Health & Science University, in Portland; Stephen H. Taplin, MD, MPH, of the National Cancer Institute; Tracy Onega, PhD, of Dartmouth Medical School, in Lebanon, NH; and Karla Kerlikowske, MD, of the University of California, San Francisco.-Story Source–The above story is reprinted from materials provided by Group Health Research Institute. \Journal Reference-Diana S.M. Buist, Rod Walker, Erin J. Aiello Bowles, Patricia A. Carney, Stephen H. Taplin, Tracy Onega, Karla Kerlikowske, Walter Clinton, and Diana L. Miglioretti. Screening Mammography Use among Current, Former, and Never Hormone Therapy Users May Not Explain Recent Declines in Breast Cancer Incidence. Cancer Epidemiol Biomarkers Prev, February 1, 2012 DOI: 10.1158/1055-9965.EPI-11-1115

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